Disease relevance of Licensure

• Since the licensure of zidovudine in 1987, an intensive clinical research effort has established the drug's efficacy in the prevention of disease progression in asymptomatic and mildly symptomatic HIV-infected persons and has established the success of lower-dose therapy in patients at all stages of disease [1].
• Herpes simplex virus infections during the decade since the licensure of acyclovir [2].
• We have treated 113 patients with zidovudine since its licensure, 80 with acquired immunodeficiency syndrome and 33 with acquired immunodeficiency syndrome-related complex [3].
• Inspired by Drachman's use of toxin to safely paralyze the hind limb in chicks, we worked out the procedures for its safe medical application and licensure from 1972 to 1989, applying it first to correct strabismus, blepharospasm, leg muscle spasm, and torticollis [4].
• Therefore, the licensure of ribavirin in 1986 for treatment of respiratory syncytial virus infections raised hopes for specific and effective therapy [5].

High impact information on Licensure

• By the time Mark Twain was born, in 1835, the political forces of Jacksonian democracy had created an era of unregulated medical practice in the United States. Licensure laws were almost nonexistent, and any citizen could practice medicine [6].
• CONCLUSIONS: In the 15 years following licensure of acyclovir, resistance to the drug remains low among immunocompetent patients [7].
• Amikacin has been used experimentally and (following licensure) without reservation at the University of California, Los Angeles, Medical Center since 1973 [8].
• BACKGROUND: Licensure of an enhanced HCV screening assay (HCV 3.0 EIA) without concurrent licensure of a complementary supplemental assay (i.e., RIBA HCV 3.0 strip immunoblot assay [RIBA-3]) decoupled screening and supplemental testing [9].
• Thus, the anticipated licensure of rimantadine, an antiviral with the same efficacy as amantadine but with fewer side effects, has been viewed as a major advance [10].

Associations of Licensure with chemical compounds

• The increased availability of zidovudine and its licensure in many countries have resulted in its widespread use [11].
• The use of pneumococcal polysaccharide vaccine has remained controversial since licensure, especially in the elderly [12].
• METHODS: Analysis of indinavir overdose reports in Merck & Co., Inc.'s safety database through the first 5 years following US licensure of indinavir [13].
• AAEM, CORD, and SAEM reach a landmark position: consensus recommendations to the Federation of State Medical Boards (FSMB) for revisions to the FSMB May 1998 policy statement on physician licensure. American Academy of Emergency Medicine. Council of Emergency Medicine Residency Directors. Society for Academic Medicine [14].
• NACNS responds to the National Council of State Boards of Nursing Uniform Advanced Practice Registered Nurse Licensure/Authority to Practice Requirements [15].

Gene context of Licensure

• It in no way related to licensure, which is a function of the appropriate legislative, health or educational authority." The same can be said for BLS; however, with the recent revisions in ECC programs, even this disclaimer has been eliminated from the most recent textbooks in BLS and ACLS [16].
• The Task Force recommends that each profession systematically determine whether appropriate items in the Curriculum Framework are included in its standardized examinations for licensure and certification and for program accreditation [17].
• Licensure issue and GST dominate March meeting of CMA Board of Directors [18].
• As a condition of licensure, the Canadian Activase for Stroke Effectiveness Study (CASES) was established to monitor the use of alteplase for AIS in Canada. The study involves multiple stakeholders [19].
• Varicella vaccine seems close to licensure in the United States. It is likely to be recommended for routine use in healthy children, either administered singly or as a combination of MMR [20].

References