Disease relevance of Sprains and Strains

• In an international study, the efficacy and toleration of piroxicam were compared with that of indomethacin, naproxen, and aspirin in three multicenter, double-blind, parallel studies involving a total of 1,290 patients with acute sprains and tendinitis [1].
• Thirty-five patients with acute strains, sprains, or low back pain were randomized to treatment (17 acetaminophen with codeine vs 18 diflunisal) [2].
• Lost time injuries, as reported in BLS data, record fewer lacerations and eye injuries, and more strains and sprains [3].
• CONCLUSIONS: Celecoxib is as effective as naproxen in treating acute first-degree or second-degree ankle sprains but causes significantly less dyspepsia [4].
• Analgesic and anti-inflammatory properties of tiaprofenic acid 200 mg t.d.s. were compared with those of aspirin 600 mg t.d.s. in 100 patients in general practice suffering from muscular rheumatic pain, fibrositis, sprains and soft tissue injuries [5].

High impact information on Sprains and Strains

• Diflunisal is comparable with glafenine in pain and with propoxyphene/paracetamol combinations and oxyphenbutazone in pain and in musculoskeletal strains and sprains [6].
• Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review [7].
• To determine the rate of noncontact ACL injury and ankle sprains in collegiate basketball and soccer [8].
• CONCLUSION: Balance as measured on a balance board and hip strength were not significant indicators for noncontact ankle sprains [9].
• Three hundred sixty-four Australian Regular Army recruits with acute ankle sprains sustained during training were randomized to treatment with either piroxicam or placebo [10].

Chemical compound and disease context of Sprains and Strains

• Fifty college athletes with acute sprains and strains from football-related activities were randomly assigned to treatment with either diflunisal or acetaminophen with codeine for seven days [11].
• A double-blind study compared ibuprofen at a dose of 2,400 mg per day and a placebo in the 1st week of treatment of 61 acute ankle sprains with varying degrees of severity [12].
• Comparison of diflunisal and acetaminophen with codeine in the treatment of mild to moderate pain due to strains and sprains [11].
• Double-blind comparison of ketoprofen and placebo in the treatment of sprains and strains [13].
• We found that significantly more serious sprains and torn ligaments occurred on grass than occurred on Tartan Turf [14].

Anatomical context of Sprains and Strains

• SETTING: Sports Medicine Research Laboratory. PARTICIPANTS: Subjects with functional ankle instability (n = 14) who reported at least 2 sprains and "giving way" sensations at their ankle joint within the year prior to testing [15].
• Thirteen had sprains or lacerations of the atlantoaxial facet joints, and one had a healed C1 fracture [16].

Gene context of Sprains and Strains

• This report is based on the data from two in vivo strain gage studies of Grade II ACL sprains [17].
• METHODS: In a prospective study, all ankle sprains presented in the ED from April to July 2004 were assessed by both a SEN and a junior doctor (house officer [HO]) randomized for first observer [18].
• Lateral ankle sprains. Part II: Acute and chronic treatment [19].
• The 285,468 compensation claims due to back strains/sprains filed in the 26 SDS states in 1979 suggest that back injuries continue to be a large and costly problem for U.S. workers and their employers [20].

Analytical, diagnostic and therapeutic context of Sprains and Strains

• Treatment of ankle sprains with joint aspiration, xylocaine infiltration, and early mobilization. Ankle sprains treated with xylocaine infiltration and early mobilization [21].

References