Chemical Compound Review:
propoxyphene [(2S,3R)-4-dimethylamino-3- methyl-1,2...
Synonyms:
Antalvic, Proxyvon, Algafan, Femadol, Proxyphen, ...
- Subacute painful myopathy from chronic propoxyphene napsylate abuse. Dalakas, M.C. JAMA (1986)
- Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine. Whitcomb, D.C., Gilliam, F.R., Starmer, C.F., Grant, A.O. J. Clin. Invest. (1989)
- Low free serum histidine concentration in rheumatoid arthritis. A measure of disease activity. Gerber, D.A. J. Clin. Invest. (1975)
- Dextropropoxyphene induced hepatotoxicity mimicking biliary tract disease. Bassendine, M.F., Woodhouse, K.W., Bennett, M., James, O.F. Gut (1986)
- Therapeutic usefulness of propoxyphene napsylate in narcotic addiction. Jasinski, D.R., Pevnick, J.S., Clark, S.C., Griffith, J.D. Arch. Gen. Psychiatry (1977)
- Propoxyphene form maintenance treatment of narcotic addiction. Woody, G.E., Mintz, J., Tennant, F., O'Brien, C.P., McLellan, A.T., Marcovici, M. Arch. Gen. Psychiatry (1981)
- A controlled trial of propoxyphene and naltrexone in patients with Tourette's syndrome. Kurlan, R., Majumdar, L., Deeley, C., Mudholkar, G.S., Plumb, S., Como, P.G. Ann. Neurol. (1991)
- The cognitive and psychomotor effects of morphine in healthy subjects: a randomized controlled trial of repeated (four) oral doses of dextropropoxyphene, morphine, lorazepam and placebo. O'Neill, W.M., Hanks, G.W., Simpson, P., Fallon, M.T., Jenkins, E., Wesnes, K. Pain (2000)
- A double-blind, placebo-controlled study of the treatment of periodic limb movements in sleep using carbidopa/levodopa and propoxyphene. Kaplan, P.W., Allen, R.P., Buchholz, D.W., Walters, J.K. Sleep. (1993)
- Propoxyphene napsylate. Lasagna, L. Ann. Intern. Med. (1976)
- Propoxyphene and acetaminophen mixture (Darvocet)--related radiation-induced pneumonitis. Halpern, J., Baerwald, H., Johnson, R., Takita, H., Ambrus, J.L. Arch. Intern. Med. (1985)
- Propoxyphene and norpropoxyphene plasma concentrations in the anephric patient. Gibson, T.P., Giacomini, K.M., Briggs, W.A., Whitman, W., Levy, G. Clin. Pharmacol. Ther. (1980)
- Pharmacokinetics of opioids in renal dysfunction. Davies, G., Kingswood, C., Street, M. Clinical pharmacokinetics. (1996)
- Acute effect of ethanol on hepatic first-pass elimination of propoxyphene in rats. Oguma, T., Levy, G. J. Pharmacol. Exp. Ther. (1981)
- Co-proxamol and suicide: preventing the continuing toll of overdose deaths. Simkin, S., Hawton, K., Sutton, L., Gunnell, D., Bennewith, O., Kapur, N. QJM : monthly journal of the Association of Physicians. (2005)
- d-Propoxyphene kinetics after single oral and intravenous doses in man. Gram, L.F., Schou, J., Way, W.L., Heltberg, J., Bodin, N.O. Clin. Pharmacol. Ther. (1979)
- Propoxyphene and norpropoxyphene: influence of diet and fluid on plasma levels. Welling, P.G., Lyons, L.L., Tse, F.L., Craig, W.A. Clin. Pharmacol. Ther. (1976)
- Nefopam and propoxyphene in episiotomy pain. Bloomfield, S.S., Barden, T.P., Mitchell, J. Clin. Pharmacol. Ther. (1980)
- Effect of hemodialysis on propoxyphene and norpropoxyphene concentrations in blood of anephric patients. Giacomini, K.M., Gibson, T.P., Levy, G. Clin. Pharmacol. Ther. (1980)
- Excretion of propoxyphene and norpropoxyphene in breast milk. Kunka, R.L., Venkataramanan, R., Stern, R.M., Ladik, C.F. Clin. Pharmacol. Ther. (1984)
- Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents. Ulens, C., Daenens, P., Tytgat, J. Cardiovasc. Res. (1999)
- Propoxyphene and norpropoxyphene: pharmacologic and toxic effects in animals. Nickander, R., Smits, S.E., Steinberg, M.I. J. Pharmacol. Exp. Ther. (1977)
- Methadone block of K+ current in squid giant fiber lobe neurons. Horrigan, F.T., Gilly, W.F. J. Gen. Physiol. (1996)
- Hemodialysis in an infant with propoxyphene intoxication. Mauer, S.M., Paxson, C.L., von Hartizsch, B., Buselmeier, T.J., Kjellstrand, C.M. Clin. Pharmacol. Ther. (1975)
- New clinical experience with tramadol. Sunshine, A. Drugs (1994)
- CYP3A4 mediates dextropropoxyphene N-demethylation to nordextropropoxyphene: human in vitro and in vivo studies and lack of CYP2D6 involvement. Somogyi, A.A., Menelaou, A., Fullston, S.V. Xenobiotica (2004)
- Profound metoprolol-induced bradycardia precipitated by acetaminophen-propoxyphene. Marraffa, J.M., Lang, L., Ong, G., Lehmann, D.F. Clin. Pharmacol. Ther. (2006)
- Phenotype/genotype relationships for the cytochrome P450 enzyme CYP2D6 in rheumatoid arthritis: influence of drug therapy and disease activity. Beyeler, C., Daly, A.K., Armstrong, M., Astbury, C., Bird, H.A., Idle, J.R. J. Rheumatol. (1994)
- Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics. Moore, R.A., McQuay, H.J. Pain (1997)
- Determination of propoxyphene and norpropoxyphene by chemical ionization mass fragmentography. Wolen, R.L., Ziege, E.A., Gruber, C.M. Clin. Pharmacol. Ther. (1975)
- Propoxyphene and norpropoxyphene plasma concentrations after oral propoxyphene in cirrhotic patients with and without surgically constructed portacaval shunt. Giacomini, K.M., Giacomini, J.C., Gibson, T.P., Levy, G. Clin. Pharmacol. Ther. (1980)