Chemical Compound Review:
Ibumetin 2-[4-(2- methylpropyl)phenyl]propanoic acid
Synonyms:
Salprofen, ibuprofen, Brufen, Motrin, Nuprin, ...
Bickel,
Dorfs,
Schmelz,
Forster,
Uhl,
Handwerker,
Harris,
Chlebowski,
Jackson,
Frid,
Ascenseo,
Anderson,
Loar,
Rodabough,
White,
McTiernan,
Van Overmeire,
Smets,
Lecoutere,
Van de Broek,
Weyler,
Degroote,
Langhendries,
Smith,
DeWitt,
Garavito,
Mallat,
Gallois,
Tao,
Habib,
Maclouf,
Mavier,
Préaux,
Lotersztajn,
- Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. Bradley, J.D., Brandt, K.D., Katz, B.P., Kalasinski, L.A., Ryan, S.I. N. Engl. J. Med. (1991)
- Ibuprofen and patent ductus arteriosus. Clyman, R.I. N. Engl. J. Med. (2000)
- Ibuprofen in patients with cystic fibrosis. Carter, E.R., Moffitt, D.R. N. Engl. J. Med. (1995)
- Effect of high-dose ibuprofen in patients with cystic fibrosis. Konstan, M.W., Byard, P.J., Hoppel, C.L., Davis, P.B. N. Engl. J. Med. (1995)
- Ibuprofen in patients with sepsis. Zimmerli, W., Widmer, A.F. N. Engl. J. Med. (1997)
- Ibuprofen, inflammation and Alzheimer disease. Wyss-Coray, T., Mucke, L. Nat. Med. (2000)
- Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women's Health Initiative. Harris, R.E., Chlebowski, R.T., Jackson, R.D., Frid, D.J., Ascenseo, J.L., Anderson, G., Loar, A., Rodabough, R.J., White, E., McTiernan, A. Cancer Res. (2003)
- Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man. Bickel, A., Dorfs, S., Schmelz, M., Forster, C., Uhl, W., Handwerker, H.O. Pain (1998)
- Possible effects of ibuprofen pretreatment on seizure duration during electroconvulsive therapy. Kessler, M.N. The Journal of clinical psychiatry. (2004)
- Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. Sheehan, D.V., Coleman, J.H., Greenblatt, D.J., Jones, K.J., Levine, P.H., Orsulak, P.J., Peterson, M., Schildkraut, J.J., Uzogara, E., Watkins, D. Journal of clinical psychopharmacology. (1984)
- Cyclooxygenases: structural, cellular, and molecular biology. Smith, W.L., DeWitt, D.L., Garavito, R.M. Annu. Rev. Biochem. (2000)
- Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. Catella-Lawson, F., Reilly, M.P., Kapoor, S.C., Cucchiara, A.J., DeMarco, S., Tournier, B., Vyas, S.N., FitzGerald, G.A. N. Engl. J. Med. (2001)
- A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus. Van Overmeire, B., Smets, K., Lecoutere, D., Van de Broek, H., Weyler, J., Degroote, K., Langhendries, J.P. N. Engl. J. Med. (2000)
- Identification and disruption of a plant shaker-like outward channel involved in K+ release into the xylem sap. Gaymard, F., Pilot, G., Lacombe, B., Bouchez, D., Bruneau, D., Boucherez, J., Michaux-Ferrière, N., Thibaud, J.B., Sentenac, H. Cell (1998)
- Transient renal failure due to simultaneous ibuprofen and aminoglycoside therapy in children with cystic fibrosis. Kovesi, T.A., Swartz, R., MacDonald, N. N. Engl. J. Med. (1998)
- The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. Bernard, G.R., Wheeler, A.P., Russell, J.A., Schein, R., Summer, W.R., Steinberg, K.P., Fulkerson, W.J., Wright, P.E., Christman, B.W., Dupont, W.D., Higgins, S.B., Swindell, B.B. N. Engl. J. Med. (1997)
- Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. Snapper, J.R., Hutchison, A.A., Ogletree, M.L., Brigham, K.L. J. Clin. Invest. (1983)
- Ibuprofen in canine endotoxin shock. Jacobs, E.R., Soulsby, M.E., Bone, R.C., Wilson, F.J., Hiller, F.C. J. Clin. Invest. (1982)
- Ibuprofen prevents oxidant lung injury and in vitro lipid peroxidation by chelating iron. Kennedy, T.P., Rao, N.V., Noah, W., Michael, J.R., Jafri, M.H., Gurtner, G.H., Hoidal, J.R. J. Clin. Invest. (1990)
- Pulmonary hypertension after ibuprofen prophylaxis in very preterm infants. Gournay, V., Savagner, C., Thiriez, G., Kuster, A., Rozé, J.C. Lancet (2002)
- P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion. Erbe, D.V., Watson, S.R., Presta, L.G., Wolitzky, B.A., Foxall, C., Brandley, B.K., Lasky, L.A. J. Cell Biol. (1993)
- An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial. Lesko, S.M., Mitchell, A.A. JAMA (1995)
- Ibuprofen inhibits cystic fibrosis transmembrane conductance regulator-mediated Cl- secretion. Devor, D.C., Schultz, B.D. J. Clin. Invest. (1998)
- Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. Srivastava, M., Perez-Atayde, A., Jonas, M.M. Gastroenterology (1998)
- Complement and neutrophil activation in the pathogenesis of ischemic myocardial injury. Crawford, M.H., Grover, F.L., Kolb, W.P., McMahan, C.A., O'Rourke, R.A., McManus, L.M., Pinckard, R.N. Circulation (1988)
- Endothelium-dependent arterial vasoconstriction after balloon angioplasty. Fischell, T.A., Nellessen, U., Johnson, D.E., Ginsburg, R. Circulation (1989)
- Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. Silverstein, F.E., Faich, G., Goldstein, J.L., Simon, L.S., Pincus, T., Whelton, A., Makuch, R., Eisen, G., Agrawal, N.M., Stenson, W.F., Burr, A.M., Zhao, W.W., Kent, J.D., Lefkowith, J.B., Verburg, K.M., Geis, G.S. JAMA (2000)
- Acute adverse reactions to ibuprofen in systemic lupus erythematosus. Finch, W.R., Strottman, M.P. JAMA (1979)
- Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. Martich, G.D., Danner, R.L., Ceska, M., Suffredini, A.F. J. Exp. Med. (1991)
- Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors. Mallat, A., Préaux, A.M., Serradeil-Le Gal, C., Raufaste, D., Gallois, C., Brenner, D.A., Bradham, C., Maclouf, J., Iourgenko, V., Fouassier, L., Dhumeaux, D., Mavier, P., Lotersztajn, S. J. Clin. Invest. (1996)
- Identification and characterization of the Arabidopsis PHO1 gene involved in phosphate loading to the xylem. Hamburger, D., Rezzonico, E., MacDonald-Comber Petétot, J., Somerville, C., Poirier, Y. Plant Cell (2002)
- Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Mitchell, J.A., Akarasereenont, P., Thiemermann, C., Flower, R.J., Vane, J.R. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Platelet-derived growth factor-BB and thrombin generate positive and negative signals for human hepatic stellate cell proliferation. Role of a prostaglandin/cyclic AMP pathway and cross-talk with endothelin receptors. Mallat, A., Gallois, C., Tao, J., Habib, A., Maclouf, J., Mavier, P., Préaux, A.M., Lotersztajn, S. J. Biol. Chem. (1998)
- Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. Schwartz, J.I., Chan, C.C., Mukhopadhyay, S., McBride, K.J., Jones, T.M., Adcock, S., Moritz, C., Hedges, J., Grasing, K., Dobratz, D., Cohen, R.A., Davidson, M.H., Bachmann, K.A., Gertz, B.J. Clin. Pharmacol. Ther. (1999)
- The bleeding time is longer than normal in hemophilia. Eyster, M.E., Gordon, R.A., Ballard, J.O. Blood (1981)
- Altered coronary vascular responsiveness to leukotrienes in alloxan-diabetic rats. Roth, D.M., Reibel, D.K., Lefer, A.M. Circ. Res. (1984)