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Disease relevance of Hidradenitis


High impact information on Hidradenitis

  • Clinical assessment of 134 patients with hidradenitis suppurativa revealed clinical evidence supporting an androgen-based endocrine disorder underlying the condition [6].
  • In response to a combined thyrotrophin releasing hormone and gonadotrophin releasing hormone test, the prolactin and TSH responses were significantly greater in the hidradenitis patients than the controls [7].
  • Etanercept: effective in the management of hidradenitis suppurativa [8].
  • Clindamycin and rifampicin combination therapy for hidradenitis suppurativa [9].
  • CK expression in PS was similar to that in hidradenitis suppurativa, suggesting that sinus epithelium may be fragile, hyperproliferative and undifferentiated [10].

Chemical compound and disease context of Hidradenitis


Anatomical context of Hidradenitis


Gene context of Hidradenitis


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  7. Hidradenitis suppurativa: evidence for an endocrine abnormality. Harrison, B.J., Kumar, S., Read, G.F., Edwards, C.A., Scanlon, M.F., Hughes, L.E. The British journal of surgery. (1985) [Pubmed]
  8. Etanercept: effective in the management of hidradenitis suppurativa. Cusack, C., Buckley, C. Br. J. Dermatol. (2006) [Pubmed]
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  10. Cytokeratin expression in pilonidal sinus. Kurokawa, I., Nishijima, S., Suzuki, K., Kusumoto, K., Sensaki, H., Shikata, N., Tsubura, A. Br. J. Dermatol. (2002) [Pubmed]
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  12. Topical clindamycin versus systemic tetracycline in the treatment of hidradenitis suppurativa. Jemec, G.B., Wendelboe, P. J. Am. Acad. Dermatol. (1998) [Pubmed]
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  15. Lithium therapy associated with hidradenitis suppurativa: case report and a review of the dermatologic side effects of lithium. Gupta, A.K., Knowles, S.R., Gupta, M.A., Jaunkalns, R., Shear, N.H. J. Am. Acad. Dermatol. (1995) [Pubmed]
  16. Androgen metabolism by isolated human axillary apocrine glands in hidradenitis suppurativa. Barth, J.H., Kealey, T. Br. J. Dermatol. (1991) [Pubmed]
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  19. Elevated parathyroid hormone-related protein and hypercalcemia in a patient with cutaneous squamous cell carcinoma complicating hidradenitis suppurativa. Welsh, D.A., Powers, J.S. South. Med. J. (1993) [Pubmed]
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