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MeSH Review

Helix-Loop-Helix Motifs

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Disease relevance of Helix-Loop-Helix Motifs


Psychiatry related information on Helix-Loop-Helix Motifs

  • MIDA1 associates with the HLH region of Id with the conserved region adjacent to eukaryotic DnaJ conserved motif within the Zuotin homology region, although it does not have any canonical HLH motif [2].

High impact information on Helix-Loop-Helix Motifs


Biological context of Helix-Loop-Helix Motifs


Associations of Helix-Loop-Helix Motifs with chemical compounds


Gene context of Helix-Loop-Helix Motifs


Analytical, diagnostic and therapeutic context of Helix-Loop-Helix Motifs


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  5. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Murre, C., McCaw, P.S., Vaessin, H., Caudy, M., Jan, L.Y., Jan, Y.N., Cabrera, C.V., Buskin, J.N., Hauschka, S.D., Lassar, A.B. Cell (1989) [Pubmed]
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  10. Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding. Chakraborty, T., Brennan, T.J., Li, L., Edmondson, D., Olson, E.N. Mol. Cell. Biol. (1991) [Pubmed]
  11. Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding. McFadden, D.G., McAnally, J., Richardson, J.A., Charité, J., Olson, E.N. Development (2002) [Pubmed]
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  16. The antineoplastic lectin of the common edible mushroom (Agaricus bisporus) has two binding sites, each specific for a different configuration at a single epimeric hydroxyl. Carrizo, M.E., Capaldi, S., Perduca, M., Irazoqui, F.J., Nores, G.A., Monaco, H.L. J. Biol. Chem. (2005) [Pubmed]
  17. Structural characterization of metallopeptides designed as scaffolds for the stabilization of nickel(II)-Fe(4)S(4) bridged assemblies by X-ray absorption spectroscopy. Musgrave, K.B., Laplaza, C.E., Holm, R.H., Hedman, B., Hodgson, K.O. J. Am. Chem. Soc. (2002) [Pubmed]
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  21. A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer. Suzuki, M., Okuyama, S., Okamoto, S., Shirasuna, K., Nakajima, T., Hachiya, T., Nojima, H., Sekiya, S., Oda, K. Oncogene (1998) [Pubmed]
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  23. Identification and cloning of a novel heterogeneous nuclear ribonucleoprotein C-like protein that functions as a transcriptional activator of the hepatitis B virus enhancer II. Tay, N., Chan, S.H., Ren, E.C. J. Virol. (1992) [Pubmed]
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