Disease relevance of Near Drowning

• Succinylcholine-induced hyperkalemia in near-drowning [1].
• A novel mutation in KVLQT1 is the molecular basis of inherited long QT syndrome in a near-drowning patient's family [2].
• Lipid peroxidation and alpha-tocopherol during an acute respiratory failure after near drowning [3].
• This study examines the value of intrathecally administered baclofen in the treatment of 19 children with severe spasticity of cerebral origin: eight of whom sustained brain injury associated with trauma, near drowning, or cardiac arrest; 10 with cerebral palsy (spastic quadriplegia); and one child with Leigh's disease [4].
• Cardiopulmonary resuscitation after near drowning and hypothermia: restoration of spontaneous circulation after vasopressin [5].

High impact information on Near Drowning

• Of 30 patients presenting after immersion or near-drowning, 50% were identified with ARI, with a mean admission serum creatinine of 0.24 +/- 0.33 mmol/L (2.7 +/- 3.7 mg/dl) [6].
• Though the treatment used recommended doses of intravenous, intrathecal and intraventricular amphotericin B, it was ineffective and the patient died 97 days after the near drowning [7].
• Succinylcholine-induced hyperkalemia in near-drowning [8].
• Twenty-six near-drowning children were assessed for neurologic damage with the Glasgow Coma Score, and for spontaneous respirations after CPR [9].
• Pulmonary function abnormalities in survivors of near drowning [10].

Chemical compound and disease context of Near Drowning

• The ineffectiveness of steroid therapy for treatment of fresh-water near-drowning [11].
• Cerebral resuscitation by use of verapamil in a victim of near-drowning [12].
• The use of the Heimlich maneuver in near drowning: Institute of Medicine report [13].
• Extracorporeal membrane oxygenation and CO2 removal in an adult after near drowning [14].
• Serum electrolytes and haemoglobin concentration were not grossly abnormal although, those with saltwater near-drowning had a significantly higher level of haemoglobin, sodium and urea compared to those with freshwater near-drowning [15].

Biological context of Near Drowning

• CONCLUSIONS: In contrast to previous studies that suggested universal LQT1 specificity, genetic heterogeneity underlies channelopathies that are suspected chiefly because of a near-drowning or drowning [16].

Gene context of Near Drowning

• Prognostic indicators in pediatric near-drowning: the Glasgow coma scale [17].
• We report the case of a 6-year-old girl who had been complaining of aching muscles for a long time, and who presented after a near-drowning incident, with extensive muscle necrosis, probably secondary to myophosphorylase deficiency-induced cramps [18].
• ABC of resuscitation. Drowning and near drowning [19].
• The epidemiological findings in 107 patients admitted to Red Cross War Memorial Children's Hospital, Cape Town, between 1976 and 1987 with a diagnosis of near-drowning are reported [20].

References