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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Mouth Breathing

 
 
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Disease relevance of Mouth Breathing

  • In ferrets, a 25-mg/kg dose of GS 4104 given twice daily reduced peak viral titers in nasal washings and eliminated constitutional responses to influenza virus infection including fever, increased nasal signs (sneezing, nasal discharge, mouth breathing), and decreased activity [1].
  • Notable clinical observations during and immediately following MIC exposure were lacrimation, perinasal/perioral wetness, respiratory difficulty (e.g., mouth breathing), decreased activity, ataxia, and hypothermia [2].
 

Psychiatry related information on Mouth Breathing

 

High impact information on Mouth Breathing

  • With restoration of the filtering action of the nose, less allergen would penetrate to the intrathoracic airways because of reduction in mouth breathing [4].
  • A total of 21 healthy volunteers (13 male, aged 22-52 yrs) were studied during mouth breathing, before and after topical upper airway anaesthesia (lidocaine) [5].
  • During mouth breathing pressures were significantly lower with nasal CPAP [6].
  • Deposition of polystyrene beads (1, 2.05, 2.8 microns mass median aerodynamic diameter (MMAD] was measured by comparing inhaled aerosols and exhaled air concentrations, for both nose and mouth breathing [7].
  • Breathing pattern and steady-state CO2 ventilatory response during mouth breathing were compared with those during nose breathing in nine healthy adults [8].
 

Chemical compound and disease context of Mouth Breathing

  • Overall, the results from the "mouth-breathing" rat model did not lead to a change in the HSE assessment of hydrogen fluoride, which remains based on experimental data obtained following "mainstream" toxicological practices [9].
  • However, no valid correlation was observed between lesion and patient age, mouth breathing, daily drug dose, plasma diphenylhydantoin level, or duration of drug intake [10].
  • CI differences emerged during mouth breathing after the olfactory ID task at Cz, C4 and T4 [11].
  • The T5-T6 coronal array showed significant CI differences after chemical exposures during nose breathing and during mouth breathing after the cognitive and olfactory ID tasks [11].
  • Skeletal and occlusal characteristics in mouth-breathing pre-school children [12].
 

Anatomical context of Mouth Breathing

  • METHODS: In Part I of the study, a fibreoptic bronchoscope was positioned in the pharynx of three volunteers lying supine and the route followed by tinted lidocaine solution instilled onto the back of the protruded tongue during mouth breathing was observed [13].
 

Gene context of Mouth Breathing

  • The influence of mouth breathing on craniofacial development has previously been demonstrated [14].
  • Persistent pattern of mouth breathing due to allergic rhinitis may difficult recovery of the myofunctional status [15].
  • The possible shortening of neck accessory muscles of respiration and mouth breathing could explain the relationship observed between TMD, CSD signs in asthmatic children and emphasize the importance of the assessment of temporomandibular and cervical spine regions in asthmatic children [16].
  • Five of 27 subjects with a history of habitual mouth breathing had a significantly lower nasal admixture (2.5 +/- 1.7% vs 25.1 +/- 15.4%; p less than 0.005), with no statistical difference in nasal resistance [17].
  • Exercise mouth breathing and supine exercise caused similar falls in nasal resistance in all subjects (mean change of Vtr, +14.1 and +14.2 L/min, respectively) [18].

References

  1. Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection. Mendel, D.B., Tai, C.Y., Escarpe, P.A., Li, W., Sidwell, R.W., Huffman, J.H., Sweet, C., Jakeman, K.J., Merson, J., Lacy, S.A., Lew, W., Williams, M.A., Zhang, L., Chen, M.S., Bischofberger, N., Kim, C.U. Antimicrob. Agents Chemother. (1998) [Pubmed]
  2. Respiratory tract changes in guinea pigs, rats, and mice following a single six-hour exposure to methyl isocyanate vapor. Fowler, E.H., Dodd, D.E. Environ. Health Perspect. (1987) [Pubmed]
  3. Nasal prongs in the detection of sleep-related disordered breathing in the sleep apnoea/hypopnoea syndrome. Ballester, E., Badia, J.R., Hernández, L., Farré, R., Navajas, D., Montserrat, J.M. Eur. Respir. J. (1998) [Pubmed]
  4. Effects of topical nasal treatment on asthma symptoms. Reed, C.E., Marcoux, J.P., Welsh, P.W. J. Allergy Clin. Immunol. (1988) [Pubmed]
  5. Effects of upper airway anaesthesia on respiratory-related evoked potentials in humans. Redolfi, S., Raux, M., Donzel-Raynaud, C., Morelot-Panzini, C., Zelter, M., Derenne, J.P., Similowski, T., Straus, C. Eur. Respir. J. (2005) [Pubmed]
  6. A nasal CPAP system. Description and comparison with facemask CPAP. Thomas, A.N., Ryan, J.P., Doran, B., Pollard, B.J. Anaesthesia. (1992) [Pubmed]
  7. Particle deposition and resistance in the noses of adults and children. Becquemin, M.H., Swift, D.L., Bouchikhi, A., Roy, M., Teillac, A. Eur. Respir. J. (1991) [Pubmed]
  8. An assessment of nasal functions in control of breathing. Tanaka, Y., Morikawa, T., Honda, Y. J. Appl. Physiol. (1988) [Pubmed]
  9. Toxicology of hydrogen fluoride in relation to major accident hazards. Meldrum, M. Regulatory toxicology and pharmacology : RTP. (1999) [Pubmed]
  10. Diphenylhydantoin-induced gingival overgrowth in man: a clinico-pathological study. Peñarrocha-Diago, M., Bagán-Sebastián, J.V., Vera-Sempere, F. J. Periodontol. (1990) [Pubmed]
  11. Quantitative EEG patterns during nose versus mouth inhalation of filtered room air in young adults with and without self-reported chemical odor intolerances. Bell, I.R., Kline, J.P., Schwartz, G.E., Peterson, J.M. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. (1998) [Pubmed]
  12. Skeletal and occlusal characteristics in mouth-breathing pre-school children. Mattar, S.E., Anselmo-Lima, W.T., Valera, F.C., Matsumoto, M.A. The Journal of clinical pediatric dentistry. (2004) [Pubmed]
  13. Anesthesia of the airway by aspiration of lidocaine. Chung, D.C., Mainland, P.A., Kong, A.S. Canadian journal of anaesthesia = Journal canadien d'anesthésie. (1999) [Pubmed]
  14. Nasal respiratory resistance and head posture: effect of intranasal corticosteroid (Budesonide) in children with asthma and perennial rhinitis. Wenzel, A., Henriksen, J., Melsen, B. American journal of orthodontics. (1983) [Pubmed]
  15. Myofunctional evaluation after surgery for tonsils hypertrophy and its correlation to breathing pattern: a 2-year-follow up. Valera, F.C., Trawitzki, L.V., Anselmo-Lima, W.T. Int. J. Pediatr. Otorhinolaryngol. (2006) [Pubmed]
  16. Correlation between signs of temporomandibular (TMD) and cervical spine (CSD) disorders in asthmatic children. Chaves, T.C., Grossi, D.B., de Oliveira, A.S., Bertolli, F., Holtz, A., Costa, D. The Journal of clinical pediatric dentistry. (2005) [Pubmed]
  17. Nasal admixture during mouth breathing in awake normal subjects. Chowanetz, W., Schott, J., Jany, B. Bulletin européen de physiopathologie respiratoire. (1987) [Pubmed]
  18. The response of the nasal airway to exercise. Olson, L.G., Strohl, K.P. Am. Rev. Respir. Dis. (1987) [Pubmed]
 
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