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MeSH Review

Nasal Lavage Fluid

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Disease relevance of Nasal Lavage Fluid


High impact information on Nasal Lavage Fluid

  • Viral titers of nasal washings in the group given inhaled and intranasal zanamivir were significantly lower than those in the placebo group [6].
  • We found that IL-6 and IFN-alpha levels in nasal lavage fluids peaked early (day 2) and correlated directly with viral titers, temperature, mucus production, and symptom scores [7].
  • In contrast to normals and minimally symptomatic volunteers, IL-6 was detected in the nasal washings from patients who developed colds after RV challenge [8].
  • Symptom scores were recorded, and the levels of histamine, prostaglandin (PG) D2, kinins, and [3H]-N-alpha-tosyl-L-arginine methyl ester (TAME)-esterase activity in nasal lavage fluids were measured [9].
  • Western analysis of nasal washings demonstrated that RV stimulated the accumulation of intracellular IL-1ra type I in all and secreted IL-1ra in a subset of volunteers [10].

Chemical compound and disease context of Nasal Lavage Fluid


Biological context of Nasal Lavage Fluid


Anatomical context of Nasal Lavage Fluid


Associations of Nasal Lavage Fluid with chemical compounds


Gene context of Nasal Lavage Fluid


Analytical, diagnostic and therapeutic context of Nasal Lavage Fluid


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  2. Analysis of the sinusitis nasal lavage fluid proteome using capillary liquid chromatography interfaced to electrospray ionization-quadrupole time of flight- tandem mass spectrometry. Casado, B., Pannell, L.K., Viglio, S., Iadarola, P., Baraniuk, J.N. Electrophoresis (2004) [Pubmed]
  3. Overview of allergic mechanisms. Ebastine has more than an antihistamine effect. Campbell, A., Michel, F.B., Bremard-Oury, C., Crampette, L., Bousquet, J. Drugs (1996) [Pubmed]
  4. Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment. Fritz, R.S., Hayden, F.G., Calfee, D.P., Cass, L.M., Peng, A.W., Alvord, W.G., Strober, W., Straus, S.E. J. Infect. Dis. (1999) [Pubmed]
  5. Chemokine concentrations in nasal washings of infants with rhinovirus illnesses. Pacifico, L., Iacobini, M., Viola, F., Werner, B., Mancuso, G., Chiesa, C. Clin. Infect. Dis. (2000) [Pubmed]
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  7. Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. Hayden, F.G., Fritz, R., Lobo, M.C., Alvord, W., Strober, W., Straus, S.E. J. Clin. Invest. (1998) [Pubmed]
  8. Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation. Zhu, Z., Tang, W., Ray, A., Wu, Y., Einarsson, O., Landry, M.L., Gwaltney, J., Elias, J.A. J. Clin. Invest. (1996) [Pubmed]
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  11. Preservation of nasopharyngeal smears for fluorescent antibody detection of Bordetella pertussis. Harris, P.P., Thomason, B., McKinney, R.M. J. Clin. Microbiol. (1980) [Pubmed]
  12. Urinary histamine metabolite elevations during experimental influenza infection. Skoner, D.P., Gentile, D.A., Fireman, P., Cordoro, K., Doyle, W.J. Ann. Allergy Asthma Immunol. (2001) [Pubmed]
  13. Neural hyperresponsiveness and nerve growth factor in allergic rhinitis. Sanico, A.M., Koliatsos, V.E., Stanisz, A.M., Bienenstock, J., Togias, A. Int. Arch. Allergy Immunol. (1999) [Pubmed]
  14. Occupational asthma and rhinitis due to glutaraldehyde: changes in nasal lavage fluid after specific inhalatory challenge test. Pałczyński, C., Walusiak, J., Ruta, U., Górski, P. Allergy (2001) [Pubmed]
  15. Prostaglandin E in the secretions of allergic rhinitis. Okazki, T., Reisman, R.E., Arbesman, C.E. Prostaglandins (1977) [Pubmed]
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  17. Protective studies with a group A streptococcal M protein vaccine. II. Challange of volenteers after local immunization in the upper respiratory tract. Polly, S.M., Waldman, R.H., High, P., Wittner, M.K., Dorfman, A. J. Infect. Dis. (1975) [Pubmed]
  18. Evidence for cytokine mediation of disease expression in adults experimentally infected with influenza A virus. Skoner, D.P., Gentile, D.A., Patel, A., Doyle, W.J. J. Infect. Dis. (1999) [Pubmed]
  19. Nasal lavage fluid concentrations of eotaxin-1 (CCL11) in naturally occurring allergic rhinitis: relationship to disease activity, nasal luminal eosinophil influx, and plasma protein exudation. Salib, R.J., Lau, L.C., Howarth, P.H. Clin. Exp. Allergy (2005) [Pubmed]
  20. Changes in levels of nerve growth factor in nasal secretions after capsaicin inhalation in patients with airway symptoms from scents and chemicals. Millqvist, E., Ternesten-Hasséus, E., Ståhl, A., Bende, M. Environ. Health Perspect. (2005) [Pubmed]
  21. Studies of IgE-dependent histamine releasing factors: heterogeneity of IgE. MacDonald, S.M., Lichtenstein, L.M., Proud, D., Plaut, M., Naclerio, R.M., MacGlashan, D.W., Kagey-Sobotka, A. J. Immunol. (1987) [Pubmed]
  22. Allergen-induced increase of eosinophil cationic protein in nasal lavage fluid: effect of the glucocorticoid budesonide. Bisgaard, H., Grønborg, H., Mygind, N., Dahl, R., Lindqvist, N., Venge, P. J. Allergy Clin. Immunol. (1990) [Pubmed]
  23. The effect of recombinant human interleukin-5 on eosinophil accumulation and degranulation in human nasal mucosa. Terada, N., Konno, A., Tada, H., Shirotori, K., Ishikawa, K., Togawa, K. J. Allergy Clin. Immunol. (1992) [Pubmed]
  24. Histamine and tryptase in nasal lavage fluid after allergen challenge: effect of 1 week of pretreatment with intranasal azelastine or systemic cetirizine. Jacobi, H.H., Skov, P.S., Poulsen, L.K., Malling, H.J., Mygind, N. J. Allergy Clin. Immunol. (1999) [Pubmed]
  25. Measurement of histamine in nasal lavage fluid: comparison of a glass fiber-based fluorometric method with two radioimmunoassays. Andersson, M., Nolte, H., Olsson, M., Skov, P.S., Pipkorn, U. J. Allergy Clin. Immunol. (1990) [Pubmed]
  26. IgA and IgG anti-ragweed antibodies in nasal secretions. Quantitative measurements of antibodies and correlation with inhibition of histamine release. Platts-Mills, T.A., von Maur, R.K., Ishizaka, K., Norman, P.S., Lichtenstein, L.M. J. Clin. Invest. (1976) [Pubmed]
  27. Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin. Cho, Y.S., Park, S.Y., Lee, C.K., Yoo, B., Moon, H.B. J. Allergy Clin. Immunol. (2003) [Pubmed]
  28. Human nasal mucosal carboxypeptidase: activity, location, and release. Ohkubo, K., Baraniuk, J.N., Merida, M., Hausfeld, J.N., Okada, H., Kaliner, M.A. J. Allergy Clin. Immunol. (1995) [Pubmed]
  29. Nasal lavage cytokines in normal, allergic, and asthmatic school-age children. Noah, T.L., Henderson, F.W., Henry, M.M., Peden, D.B., Devlin, R.B. Am. J. Respir. Crit. Care Med. (1995) [Pubmed]
  30. The kinetics of allergen-induced eotaxin level in nasal lavage fluid: its key role in eosinophil recruitment in nasal mucosa. Terada, N., Hamano, N., Kim, W.J., Hirai, K., Nakajima, T., Yamada, H., Kawasaki, H., Yamashita, T., Kishi, H., Nomura, T., Numata, T., Yoshie, O., Konno, A. Am. J. Respir. Crit. Care Med. (2001) [Pubmed]
  31. Inhalation of swine dust induces cytokine release in the upper and lower airways. Wang, Z., Larsson, K., Palmberg, L., Malmberg, P., Larsson, P., Larsson, L. Eur. Respir. J. (1997) [Pubmed]
  32. PLUNC in human nasal lavage fluid: multiple isoforms that bind to lipopolysaccharide. Ghafouri, B., Kihlström, E., Tagesson, C., Lindahl, M. Biochim. Biophys. Acta (2004) [Pubmed]
  33. Nasal response to capsaicin in patients with allergic rhinitis and in healthy volunteers: effect of colchicine. Roche, N., Lurie, A., Authier, S., Dusser, D.J. Am. J. Respir. Crit. Care Med. (1995) [Pubmed]
  34. Nasal neutrophilia and release of myeloperoxidase induced by nasal challenge with platelet activating factor: different degrees of responsiveness in atopic and nonatopic subjects. Miadonna, A., Milazzo, N., Lorini, M., Sala, A., Tedeschi, A. J. Allergy Clin. Immunol. (1996) [Pubmed]
  35. Effect of six-hour exposure to nitrogen dioxide on early-phase nasal response to allergen challenge in patients with a history of seasonal allergic rhinitis. Wang, J.H., Devalia, J.L., Duddle, J.M., Hamilton, S.A., Davies, R.J. J. Allergy Clin. Immunol. (1995) [Pubmed]
  36. Demonstration of different forms of the anti-inflammatory proteins lipocortin-1 and Clara cell protein-16 in human nasal and bronchoalveolar lavage fluids. Lindahl, M., Svartz, J., Tagesson, C. Electrophoresis (1999) [Pubmed]
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