The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Bronchoscopes


High impact information on Bronchoscopes

  • To evaluate the effects of LTB4 in the normal human lung, we instilled LTB4 (5 X 10(-7)M, 10 ml) into a subsegment of the right middle lobe and 0.9% NaCl (10 ml) into a subsegment of the lingula using a fiberoptic bronchoscope in 12 healthy human volunteers [6].
  • A bronchoscope was used in anesthetized dogs to record peripheral airway resistance (Rp); to test airway reactivity to NK A (NKA), substance P, and hypertonic saline; and to examine HIB before and after combined treatment with NK-1 (CP 99,994) and NK-2 (SR 48,968) receptor antagonists [7].
  • An endoscopic washing pipe (Olympus) that can be inserted into the channel of a bronchoscope was used [8].
  • With a constant flow of gas (5% CO2 in air) through one lumen of the catheter, pressure at the tip of the bronchoscope was measured with the subject breath-holding at FRC [9].
  • Peripheral airways resistance (Rp) was measured at baseline and after saline, histamine (10, 50, 100 mg/ml) and isoproterenol (2 mg/ml) challenge through the bronchoscope [9].

Chemical compound and disease context of Bronchoscopes

  • Measurements of Rcoll were made with either 5 or 10% CO2 and with air (hypocapnia) in 29 anesthetized sheep, ages 6 mo to 10 yr, with the wedged bronchoscope technique [10].
  • We used a wedged bronchoscope technique in conjunction with an in situ isolated perfused left lower lobe preparation in anesthetized dogs to examine cold-associated airway modulation of peripheral lung responses to dry airflow, hypocapnia, and aerosols of histamine and hypertonic NaCl [11].
  • Nineteen patients with cancer involving the tracheobronchial tree (a total of 20 carcinomas) have completed at least one course of hematoporphyrin derivative phototherapy administered via the flexible fiberoptic bronchoscope [12].
  • PURPOSE: We report the use of an ultrathin fibreoptic bronchoscope (Olympus N20: external diameter: 2.2 mm) as the means of airway endoscopic monitoring during anaesthesia for the excision of mediastinal bronchogenic cysts in two young children [13].
  • A Teflon catheter was passed through a flexible bronchoscope and Super Glue (butyl or methyl methacrylate) was deposited into the fistula [14].

Biological context of Bronchoscopes


Anatomical context of Bronchoscopes

  • METHODS: The TMV was measured in seven healthy female sheep by radiographically tracking the motion of small discs of tantalum inserted into the trachea through a bronchoscope [20].
  • Anaesthesia of the mucosa, tested by passing a bronchoscope through the nose to the oropharynx was best with lignocaine spray or gel [21].
  • (99m)Tc-DTPA (6-10 microl) was delivered by a microspray nozzle inserted through a bronchoscope to a fourth-generation bronchus both before and 1 h after bradykinin (20 ml; 10(-6) M) had been infused through a cannulated and perfused bronchial artery [22].
  • The thin calibre and manoeuvrability of the flexible fibreoptic bronchoscope makes fibreoptic intubation an excellent technique of airway management in cicatricial membranes of the pharynx [23].
  • The present study has investigated ultrastructural localization of anionic sites on the luminal surface of the alveolar epithelium of goat lung by direct airway instillation of cationized ferritin (CF) in the cranial lobe of the right lung through a bronchoscope [24].

Associations of Bronchoscopes with chemical compounds


Gene context of Bronchoscopes

  • Sterilized bronchoscopes were flushed with sterile saline, and the collected eluate was submitted for PCR amplification of IS6110 sequences and exon 8 of the human p53 gene [29].
  • All BAL samples tested contained detectable endotoxin as did all saline aliquots instilled through bronchoscopes [30].
  • Lavage limited to an isolated lobe was performed on multiple occasions using a cuffed fiberoptic bronchoscope in a patient with alveolar proteinosis [31].
  • BAL was obtained by sequential instillation and aspiration of 5 to 25 mL aliquots of sterile saline solution through a bronchoscope wedged in a radiographically involved subsegment [32].
  • A manoeuvre for using the flexible fibreoptic bronchoscope through the Intubating Laryngeal Mask Airway [33].

Analytical, diagnostic and therapeutic context of Bronchoscopes


  1. Inhaled nitric oxide attenuates bronchoconstriction in canine peripheral airways. Gwyn, D.R., Lindeman, K.S., Hirshman, C.A. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  2. Disinfection of the flexible fibreoptic bronchoscope against Mycobacterium tuberculosis and M gordonae. Davis, D., Bonekat, H.W., Andrews, D., Shigeoka, J.W. Thorax (1984) [Pubmed]
  3. Recovery of the human immunodeficiency virus from fibreoptic bronchoscopes. Hanson, P.J., Gor, D., Clarke, J.R., Chadwick, M.V., Gazzard, B., Jeffries, D.J., Gaya, H., Collins, J.V. Thorax (1991) [Pubmed]
  4. Management of malignant airway obstruction: clinical and dosimetric considerations using an iridium-192 afterloading technique in conjunction with the neodymium-YAG laser. Schray, M.F., McDougall, J.C., Martinez, A., Edmundson, G.K., Cortese, D.A. Int. J. Radiat. Oncol. Biol. Phys. (1985) [Pubmed]
  5. Intratumoral administration of cisplatin through a bronchoscope followed by irradiation for treatment of inoperable non-small cell obstructive lung cancer. Celikoglu, F., Celikoglu, S.I., York, A.M., Goldberg, E.P. Lung Cancer (2006) [Pubmed]
  6. Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability. Martin, T.R., Pistorese, B.P., Chi, E.Y., Goodman, R.B., Matthay, M.A. J. Clin. Invest. (1989) [Pubmed]
  7. Neurokinins modulate hyperventilation-induced bronchoconstriction in canine peripheral airways. Freed, A.N., McCulloch, S., Meyers, T., Suzuki, R. Am. J. Respir. Crit. Care Med. (2003) [Pubmed]
  8. Coarse spray delivery to a localized region of the pulmonary airways for gene therapy. Cipolla, D.C., Gonda, I., Shak, S., Kovesdi, I., Crystal, R., Sweeney, T.D. Hum. Gene Ther. (2000) [Pubmed]
  9. Direct assessment of small airways reactivity in human subjects. Wagner, E.M., Bleecker, E.R., Permutt, S., Liu, M.C. Am. J. Respir. Crit. Care Med. (1998) [Pubmed]
  10. Hypocapnia does not alter collateral ventilation in sheep. Hudak, B.B., Terry, P.B., Menkes, H.A., Jones, M.D., Traystman, R.J. J. Appl. Physiol. (1990) [Pubmed]
  11. Airway cooling: stimulus specific modulation of airway responsiveness in the canine lung periphery. Freed, A.N., Stream, C.E. Eur. Respir. J. (1991) [Pubmed]
  12. Hematoporphyrin derivative phototherapy in the treatment of bronchogenic carcinoma. Cortese, D.A., Kinsey, J.H. Chest (1984) [Pubmed]
  13. Excision of bronchogenic cysts in children using an ultrathin fibreoptic bronchoscope. Monrigal, J.P., Granry, J.C. Canadian journal of anaesthesia = Journal canadien d'anesthésie. (1996) [Pubmed]
  14. Endoscopic management of large, postresection bronchopleural fistulae with methacrylate adhesive (Super Glue). Wood, R.E., Lacey, S.R., Azizkhan, R.G. J. Pediatr. Surg. (1992) [Pubmed]
  15. A comparison of the relaxant effects of olprinone and aminophylline on methacholine-induced bronchoconstriction in dogs. Hirota, K., Yoshioka, H., Kabara, S., Kudo, T., Ishihara, H., Matsuki, A. Anesth. Analg. (2001) [Pubmed]
  16. Nebulized lidocaine administered to infants and children undergoing flexible bronchoscopy. Gjonaj, S.T., Lowenthal, D.B., Dozor, A.J. Chest (1997) [Pubmed]
  17. Comparison of a solution of super-oxidized water (Sterilox) with glutaraldehyde for the disinfection of bronchoscopes, contaminated. Middleton, A.M., Chadwick, M.V., Sanderson, J.L., Gaya, H. J. Hosp. Infect. (2000) [Pubmed]
  18. Special precautions reduce oropharyngeal contamination in bronchoalveolar lavage for bacteriologic studies. Pang, J.A., Cheng, A.F., Chan, H.S., French, G.L. Lung (1989) [Pubmed]
  19. Effects of topical laryngeal lidocaine on sympathetic response to rigid panendoscopy under general anesthesia. Gaumann, D.M., Tassonyi, E., Fathi, F., Griessen, M. ORL J. Otorhinolaryngol. Relat. Spec. (1992) [Pubmed]
  20. Tracheal mucus velocity remains normal in healthy sheep intubated with a new endotracheal tube with a novel laryngeal seal. Trawöger, R., Kolobow, T., Cereda, M., Sparacino, M.E. Anesthesiology (1997) [Pubmed]
  21. Topical anaesthesia of the nasal mucosa for fibreoptic airway endoscopy. Randell, T., Yli-Hankala, A., Valli, H., Lindgren, L. British journal of anaesthesia. (1992) [Pubmed]
  22. Bronchial edema alters (99m)Tc-DTPA clearance from the airway surface in sheep. Foster, W.M., Wagner, E.M. J. Appl. Physiol. (2001) [Pubmed]
  23. Fibreoptic intubation in cicatricial membranes of the pharynx. Divatia, J.V., Upadhye, S.M., Sareen, R. Anaesthesia. (1992) [Pubmed]
  24. An uptake of cationized ferritin by alveolar type I cells in airway-instilled goat lung: distribution of anionic sites on the epithelial surface. Atwal, O.S., Viel, L., Minhas, K.J. J. Submicrosc. Cytol. Pathol. (1990) [Pubmed]
  25. Dissociation of bradykinin-induced plasma exudation and reactivity in the peripheral airways. Berman, A.R., Liu, M.C., Wagner, E.M., Proud, D. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  26. Allergen challenge-induced entry of alpha 2-macroglobulin and tryptase into human nasal and bronchial airways. Svensson, C., Grönneberg, R., Andersson, M., Alkner, U., Andersson, O., Billing, B., Gilljam, H., Greiff, L., Persson, C.G. J. Allergy Clin. Immunol. (1995) [Pubmed]
  27. Local anaesthesia for fibreoptic bronchoscopy: transcricoid injection or the "spray as you go" technique? Webb, A.R., Fernando, S.S., Dalton, H.R., Arrowsmith, J.E., Woodhead, M.A., Cummin, A.R. Thorax (1990) [Pubmed]
  28. Suitability of and tolerance to Iotrolan 300 in bronchography via the fibreoptic bronchoscope. Morcos, S.K., Anderson, P.B., Baudouin, S.V., Clout, C., Fairlie, N., Baudouin, C., Warnock, N. Thorax (1990) [Pubmed]
  29. Amplification of residual DNA sequences in sterile bronchoscopes leading to false-positive PCR results. Kaul, K., Luke, S., McGurn, C., Snowden, N., Monti, C., Fry, W.A. J. Clin. Microbiol. (1996) [Pubmed]
  30. Intrapulmonary cytokine accumulation following BAL and the role of endotoxin contamination. Nelson, M.E., Wald, T.C., Bailey, K., Wesselius, L.J. Chest (1999) [Pubmed]
  31. Alveolar proteinosis. Lobar lavage by fiberoptic bronchoscopic technique. Brach, B.B., Harrell, J.H., Moser, K.M. Chest (1976) [Pubmed]
  32. Noninvasive positive-pressure ventilation via face mask during bronchoscopy with BAL in high-risk hypoxemic patients. Antonelli, M., Conti, G., Riccioni, L., Meduri, G.U. Chest (1996) [Pubmed]
  33. A manoeuvre for using the flexible fibreoptic bronchoscope through the Intubating Laryngeal Mask Airway. Panjwani, S., Seymour, P., Pandit, J.J. Anaesthesia. (2001) [Pubmed]
  34. Airway surface liquid recovered by lavage with perfluorocarbon liquid in cats. Southern, K.W., Funkhouser, W.K., Kazachkova, I., Godfrey, V.L., Fordham, L.A., Gatzy, J.T., Barker, P.M. Eur. J. Clin. Invest. (2002) [Pubmed]
  35. Fiberoptic bronchopulmonary lavage for alveolar proteinosis in a patient with only one lung. Heymach, G.J., Shaw, R.C., McDonald, J.A., Vest, J.V. Chest (1982) [Pubmed]
  36. Ultrathin bronchoscopic barium marking with virtual bronchoscopic navigation for fluoroscopy-assisted thoracoscopic surgery. Asano, F., Shindoh, J., Shigemitsu, K., Miya, K., Abe, T., Horiba, M., Ishihara, Y. Chest (2004) [Pubmed]
  37. Photodynamic therapy of endobronchial tumors. McCaughan, J.S., Williams, T.E., Bethel, B.H. Lasers in surgery and medicine. (1986) [Pubmed]
  38. Pneumoperitoneum as a risk factor for endobronchial intubation during laparoscopic gynecologic surgery. Lobato, E.B., Paige, G.B., Brown, M.M., Bennett, B., Davis, J.D. Anesth. Analg. (1998) [Pubmed]
WikiGenes - Universities