Disease relevance of Ascaridia

• At a dose of 15 mg/kg body weight, pyrantel tartrate was 18-51, 99-63, 100 and 100 per cent effective in chickens treated at 10, 20, 30 and 40 days respectively after infection with Ascaridia galli [1].

High impact information on Ascaridia

• A soluble GSH transferase of the parasitic nematode Ascaridia galli has now been purified which shows high activity and specificity in the GSH-dependent isomerization of PGH to PGE, comparable to that of the rat spleen enzyme in its isomerization of PGH to PGD, and similarly stimulates the activity of prostaglandin H synthase [2].
• Purification and characterization of prostaglandin-H E-isomerase, a sigma-class glutathione S-transferase, from Ascaridia galli [2].
• 1. Respiration in the parasitic nematode worm Ascaridia galli was inhibited at O2 concentrations in excess of 255 microM, and an apparent Km,O2 of 174 microM was determined [3].
• A comparison of the interaction of anthelmintic benzimidazoles with tubulin isolated from mammalian tissue and the parasitic nematode Ascaridia galli [4].
• ACh, AF3 and AF4 were also found to contract Ascaridia galli somatic muscle with EC50S of 13 +/- 3 microM, 721 +/- 236 nM and 371 +/- 177 nM, respectively (n = 7) [5].

Biological context of Ascaridia

• This paper reports on the pharmacokinetics and the efficacy of febantel against Capillaria obsignata and Ascaridia columbae in the racing pigeon [6].
• The effect of piperazine adipate and parbendazole on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae [7].

Anatomical context of Ascaridia

• Metabolic fate of alanine in cuticle hypodermis muscle system of the fowl nematode Ascaridia galli [8].

Associations of Ascaridia with chemical compounds

• Adult Ascaridia galli incorporate label from [U-14C] serine into various intermediates of sphingomyelin synthesis (ketosphinganine, sphinganine, sphingosine, ceramide and sphingomyelin) [9].
• Cyclic AMP-dependent and independent protein kinases in Ascaridia galli [10].
• Evaluation of three water-suspensible formulations of fenbendazole against Ascaridia galli infection in broiler chickens [11].
• Effect of parbendazole and piperazine adipate on the activity of some enzymes of Ascaridia galli and Heterakis gallinae [12].
• Chickens treated with albendazole had lower Ascaridia and Heterakis faecal egg counts than non-treated chickens [13].

Gene context of Ascaridia

• Ag-NPA-1 (AgFABP), a 15 kDa lipid binding protein (LBP) from Ascaridia galli, is a member of the nematode polyprotein allergen/antigen (NPA) family [14].
• A structure-activity study of the neuropeptide PF1, SDPNFLRFamide, using the dorsal body wall muscle of the chicken nematode, Ascaridia galli [15].
• Study of the acetylcholinesterase activity of Ascaridia galli: kinetic properties and the effect of anthelmintics [16].
• Properties of an arylalkylamine N-acetyltransferase from the nematode, Ascaridia galli [17].
• Effect of some anthelmintics on malate dehydrogenase activity and mortality in two avian nematodes Ascaridia galli and Heterakis gallinae [18].

References