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MeSH Review

Morus

 
 
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High impact information on Morus

  • Quantitative analysis of aglycone quercetin in mulberry leaves (Morus alba L.) by capillary zone electrophoresis [1].
  • Mulberry (Morus alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice [2].
  • A new prenyltransferase (PT) enzyme derived from the microsomal fractions of cell cultures of Morus nigra was shown to be able to prenylate exclusively chalcones with a 2',4'-dihydroxy substitution and the isoflavone genistein [3].
  • Molecular characterization of a hydroxymethylglutaryl-CoA reductase gene from mulberry (Morus alba L.) [4].
  • Five new Diels-Alder type adducts, mongolicins A - E, and nine known compounds, mongolicin F, chalcomoracin, mulberrofuran T, mulberrofuran G, mulberrofuran F, albanol B, kuwanon O, mulberrofuran H and kuwanon H, were isolated from the stem and root bark of Morus mongolica [5].
 

Biological context of Morus

  • The modulatory effect of the methanolic extract of Morus indica on 12-O-tetradecanoyl-phorbol-13-acetate (TPA) induced oxidative stress and 7,12-dimethylbenz(a)anthracene induced and croton oil (0.5% per mouse/0.2 mL acetone, v/v) promoted skin tumourigenesis in Swiss albino mice was studied [6].
  • Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats [7].
  • Conidial germination and hyphal growth of P. corylea on the leaf surface of two susceptible mulberry genotypes, viz., Kanva 2 (K2) and Victory 1 (V1) varieties of Morus indica, and on two resistant species, viz,, M. laevigata and M. serrata were studied by scanning electron microscopy [8].
 

Anatomical context of Morus

  • Kuwanon G and H, isolated from the methanol extract of Morus bombycis, inhibited specific binding of [125I]gastrin-releasing peptide (GRP) to GRP-preferring receptors in murine Swiss 3T3 fibroblasts with Ki values of 470 and 290 nM, respectively [9].
  • Effects of Morus alba leaf extract on the production of nitric oxide, prostaglandin E2 and cytokines in RAW264.7 macrophages [10].
 

Associations of Morus with chemical compounds

  • The effects of dietary consumption of mulberry (Morus alba L.) leaves and their major flavonol glycoside, quercetin 3-(6-malonylglucoside) (Q3MG), on the development of atherosclerotic lesions, in relation to the susceptibility of plasma LDL to oxidative modification, was studied in LDL receptor-deficient (LDLR-/-) mice [2].
  • Five new compounds, named guangsangons A (1), B (5), C (6), D (7), and E (8), along with four known compounds, albafuran C (2), kuwanon X (3), kuwanon P (4), and kuwanon Y (9) were isolated from Morus macroura Miq.. Their structures were determined by means of spectroscopic analyses and chemical methods [11].
  • MornigaM, a lectin from Morus nigra, belongs to the mannose-binding subgroup of the family of jacalin-related plant lectins [12].
  • A rapid and reliable method suitable for assays of a large number of Morus alba leaves for 1-deoxynojirimycin (DNJ) has been developed [13].
  • Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba [14].
 

Gene context of Morus

 

Analytical, diagnostic and therapeutic context of Morus

References

  1. Quantitative analysis of aglycone quercetin in mulberry leaves (Morus alba L.) by capillary zone electrophoresis. Suntornsuk, L., Kasemsook, S., Wongyai, S. Electrophoresis (2003) [Pubmed]
  2. Mulberry (Morus alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice. Enkhmaa, B., Shiwaku, K., Katsube, T., Kitajima, K., Anuurad, E., Yamasaki, M., Yamane, Y. J. Nutr. (2005) [Pubmed]
  3. Chalcone dimethylallyltransferase from Morus nigra cell cultures. Substrate specificity studies. Vitali, A., Giardina, B., Delle Monache, G., Rocca, F., Silvestrini, A., Tafi, A., Botta, B. FEBS Lett. (2004) [Pubmed]
  4. Molecular characterization of a hydroxymethylglutaryl-CoA reductase gene from mulberry (Morus alba L.). Jain, A.K., Vincent, R.M., Nessler, C.L. Plant Mol. Biol. (2000) [Pubmed]
  5. Five new diels-alder type adducts from the stem and root bark of Morus mongolica. Kang, J., Chen, R.Y., Yu, D.Q. Planta Med. (2006) [Pubmed]
  6. Modulatory effect of Morus indica against two-stage skin carcinogenesis in Swiss albino mice: possible mechanism by inhibiting aryl hydrocarbon hydroxylase. Prasad, L., Khan, T.H., Sehrawat, A., Sultana, S. J. Pharm. Pharmacol. (2004) [Pubmed]
  7. Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats. Singab, A.N., El-Beshbishy, H.A., Yonekawa, M., Nomura, T., Fukai, T. Journal of ethnopharmacology. (2005) [Pubmed]
  8. Tropic failure of Phyllactinia corylea contributes to the mildew resistance of mulberry genotypes. Babu, A.M., Kumar, J.S., Kumar, V., Sarkar, A., Datta, R.K. Mycopathologia (2002) [Pubmed]
  9. Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry. Mihara, S., Hara, M., Nakamura, M., Sakurawi, K., Tokura, K., Fujimoto, M., Fukai, T., Nomura, T. Biochem. Biophys. Res. Commun. (1995) [Pubmed]
  10. Effects of Morus alba leaf extract on the production of nitric oxide, prostaglandin E2 and cytokines in RAW264.7 macrophages. Choi, E.M., Hwang, J.K. Fitoterapia (2005) [Pubmed]
  11. Bioactive diels-alder type adducts from the stem bark of Morus macroura. Dai, S.J., Mi, Z.M., Ma, Z.B., Li, S., Chen, R.Y., Yu, D.Q. Planta Med. (2004) [Pubmed]
  12. The crystals of a mannose-specific jacalin-related lectin from Morus nigra are merohedrally twinned. Rabijns, A., Verboven, C., Novoa de Armas, H., Van Damme, E.J., Peumans, W.J., De Ranter, C.J. Acta Crystallogr. D Biol. Crystallogr. (2001) [Pubmed]
  13. Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversed-phase high-performance liquid chromatography. Kim, J.W., Kim, S.U., Lee, H.S., Kim, I., Ahn, M.Y., Ryu, K.S. Journal of chromatography. A. (2003) [Pubmed]
  14. Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba. Oh, H., Ko, E.K., Jun, J.Y., Oh, M.H., Park, S.U., Kang, K.H., Lee, H.S., Kim, Y.C. Planta Med. (2002) [Pubmed]
  15. Discovering COX-inhibiting constituents of Morus root bark: activity-guided versus computer-aided methods. Rollinger, J.M., Bodensieck, A., Seger, C., Ellmerer, E.P., Bauer, R., Langer, T., Stuppner, H. Planta Med. (2005) [Pubmed]
  16. Oxyresveratrol as the potent inhibitor on dopa oxidase activity of mushroom tyrosinase. Shin, N.H., Ryu, S.Y., Choi, E.J., Kang, S.H., Chang, I.M., Min, K.R., Kim, Y. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  17. Hypolipidemic and antioxidant effects of Morus alba L. (Egyptian mulberry) root bark fractions supplementation in cholesterol-fed rats. El-Beshbishy, H.A., Singab, A.N., Sinkkonen, J., Pihlaja, K. Life Sci. (2006) [Pubmed]
  18. Protein tyrosine phosphatase 1B inhibitors from Morus root bark. Cui, L., Na, M., Oh, H., Bae, E.Y., Jeong, D.G., Ryu, S.E., Kim, S., Kim, B.Y., Oh, W.K., Ahn, J.S. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
 
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