Disease relevance of Meckel Diverticulum

• The results indicate the potential use of cimetidine for enhanced visualization of Meckel's diverticulum, Barrett's esophagus, and the stomach, with 99mTc-pertechnetate [1].
• In a six-year-old girl with recurrent abdominal pain, abdominal imaging with technetium-99m pertechnetate was performed to detect ectopic gastric mucosa in a Meckel's diverticulum but was negative in this respect [2].
• Neoplasms arising in Meckel's diverticulum or involving hernia sacs are rare [3].
• An obese patient, not diabetic, treated with metformin for some weeks, was referred to us with severe inferior digestive hemorrhage, diagnosed with Meckel's diverticulum [4].
• A 10 year old white girl, investigated for the possible presence of a Meckel's diverticulum, was found to have a partial volvulus of the proximal jejunal loop that exhibited intense localization of Technetium-99m Pertechnetate [5].

High impact information on Meckel Diverticulum

• Cimetidine and Meckel's diverticulum [6].
• Meckel's diverticulum: possible detection by combining pentagastrin with histamine H2 receptor blocker [7].
• Pentagastrin stimulation of technetium-99m uptake by ectopic gastric muscosa in a Meckel's diverticulum [8].
• Additionally, the results indicate caution in the interpretation of scans in patients with suspected Meckel's diverticulum since, in the rat and probably in the human, significant amounts of technetium can accumulate in the gut apart from gastric secretion and intestinal transit [9].
• Re: Bleeding from a Meckel's diverticulum after the use of ibuprofen [10].

Chemical compound and disease context of Meckel Diverticulum

• We report on a 27-yr-old man who bled from a Meckel's diverticulum after receiving oral ibuprofen, a nonsteroidal antiinflammatory drug [11].
• The details of a young adult patient who presented with chronic gastro-intestinal blood loss as a complication of Meckel's diverticulum are reported [12].
• The authors describe two cases of Meckel's diverticulum containing radiopaque stones that were diagnosed peroperatively by plain abdominal films and barium small bowel studies [13].
• Meckel's diverticulum is classically described to mimic acute appendicitis when inflamed as well as being a cause of unexplained luminal gastrointestinal bleeding [14].
• Digestive hemorrhage caused by a Meckel's diverticulum in a metformin-treated patient: is there any connection [4]?

Anatomical context of Meckel Diverticulum

• Technetium-99m labeled red blood cell scan and the Meckel's diverticulum scan failed to demonstrate the bleeding point [15].
• A small dilated segment of ileum was also present at the site where Meckel's diverticulum would be expected, which was not causing obstruction to the luminal contents [16].

Gene context of Meckel Diverticulum

• Radionuclide imaging of Meckel's diverticulum: cimetidine versus pentagastrin plus glucagon [17].
• METHODS: A 10-year retrospective review identified 45 children with Meckel's diverticulum [18].
• A canine model simulating Meckel's diverticulum was used to evaluate the effects of pentagastrin, glucagon, and a combination of the two hormones on the gastrointestinal localization of 99mTc [19].
• We report a case of newborn with a giant Meckel's diverticulum and congenital diaphragmatic hernia [20].
• Uptake of iodine-131 by a Meckel's diverticulum mimicking metastatic thyroid cancer [21].

Analytical, diagnostic and therapeutic context of Meckel Diverticulum

• RESULTS: In 39 patients (13.9%), appendectomy was performed along with 19 enucleated or endocoagulated ovarian cysts, 8 adhesiolyses, 6 transperitoneal hernioplasties (4 right and 2 left), 2 cholecystectomies, 2 excisions of a Meckel diverticulum, 1 aspiration and suture of a right tubal pregnancy and 1 electrodesiccation of pelvic endometriosis [22].

References