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MeSH Review


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Disease relevance of Appendectomy


High impact information on Appendectomy

  • Chronic ANP suppression was produced by bilateral atrial appendectomies before the production of ELVD by rapid ventricular pacing (ELVD-APPX, n = 5) [6].
  • However, interleukin 4 production was below detectable levels both before and after appendectomy [7].
  • Plasma vasopressin, measured at the end of volume expansion, was significantly lower in animals subjected to left atrial appendectomy [8].
  • Duration of both parenteral and oral analgesic use favored laparoscopic appendectomy (2.0 days versus 1.2 days, and 8.0 days versus 5.4 days, p < 0.05) [9].
  • 1735 patients undergoing appendectomy were evaluable, and half of these patients received 2 g of cefoxitin before undergoing operation [10].

Chemical compound and disease context of Appendectomy


Biological context of Appendectomy


Anatomical context of Appendectomy


Associations of Appendectomy with chemical compounds

  • Two patients with intraperitoneal complications after appendectomy had a significantly increased urea production [24].
  • Systemic prophylactic antibiotics can successfully reduce septic complications after appendectomy for nonperforated appendicitis, and a single drug (cefamandole) directed at the facultative pathogens is as effective as double drug therapy, which includes specific anaerobic coverage [25].
  • Concentrations of cefmetazole in plasma and tissue resulting from peri-incisional administration before appendectomy [26].
  • We conclude that measuring serotonin may be of value in confirming or excluding the diagnosis of early acute appendicitis where the physical signs are equivocal, and thus helps reduce unnecessary appendectomies [27].
  • Similarly, when given intravenously prior to appendectomy, tinidazole reduced the incidence of postoperative infection in some subgroups of patients [28].

Gene context of Appendectomy


Analytical, diagnostic and therapeutic context of Appendectomy


  1. Primary appendectomy. The effect of prophylatic cephaloridine on postoperative wound infection. Foster, P.D., O'Toole, R.D. JAMA (1978) [Pubmed]
  2. Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Pabinger, I., Schneider, B. Arterioscler. Thromb. Vasc. Biol. (1996) [Pubmed]
  3. General and gastrointestinal tract surgery in France. Fingerhut, A., Hay, J.M., Millat, B., Lacaine, F., Fagniez, P.L. Archives of surgery (Chicago, Ill. : 1960) (1998) [Pubmed]
  4. Combined preoperative antibiotic therapy and intraoperative topical povidone-iodine. Reduction of wound sepsis following emergency appendectomy. Sherlock, D.J., Ward, A., Holl-Allen, R.T. Archives of surgery (Chicago, Ill. : 1960) (1984) [Pubmed]
  5. The treatment of complicated appendicitis in children. What is the gold standard? Elmore, J.R., Dibbins, A.W., Curci, M.R. Archives of surgery (Chicago, Ill. : 1960) (1987) [Pubmed]
  6. A functional role for endogenous atrial natriuretic peptide in a canine model of early left ventricular dysfunction. Stevens, T.L., Burnett, J.C., Kinoshita, M., Matsuda, Y., Redfield, M.M. J. Clin. Invest. (1995) [Pubmed]
  7. A patient with improvement of ulcerative colitis after appendectomy. Okazaki, K., Onodera, H., Watanabe, N., Nakase, H., Uose, S., Matsushita, M., Kawanami, C., Imamura, M., Chiba, T. Gastroenterology (2000) [Pubmed]
  8. Role of right and left atria in natriuresis and atrial natriuretic factor release during blood volume changes in the conscious rat. Garcia, R., Cantin, M., Thibault, G. Circ. Res. (1987) [Pubmed]
  9. A prospective randomized trial comparing open versus laparoscopic appendectomy. Frazee, R.C., Roberts, J.W., Symmonds, R.E., Snyder, S.K., Hendricks, J.C., Smith, R.W., Custer, M.D., Harrison, J.B. Ann. Surg. (1994) [Pubmed]
  10. Antibiotic prophylaxis in acute nonperforated appendicitis. The Danish Multicenter Study Group III. Bauer, T., Vennits, B., Holm, B., Hahn-Pedersen, J., Lysen, D., Galatius, H., Kristensen, E.S., Graversen, P., Wilhelmsen, F., Skjoldborg, H. Ann. Surg. (1989) [Pubmed]
  11. Parenteral nutrition with essential amino acids in pretransplantation anephrics. Kaminski, M.V., Light, J.A., Briggs, W.A. JPEN. Journal of parenteral and enteral nutrition. (1978) [Pubmed]
  12. Prevention of postoperative wound infection after appendectomy by local application of tinidazole: a double-blind study. Eklund, A.E., Tunevall, T.G. World journal of surgery. (1987) [Pubmed]
  13. Management of wound infection after appendectomy: are parenteral antibiotics useful? Harahsheh, B., Hiyasat, B., Abulail, A., Al-Basheer, M. Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ. (2002) [Pubmed]
  14. A controlled study of single dosage cefamandole in the prophylaxis of wound infections in appendectomy. Gledhill, T., Odurny, A., Weaver, P.C. Surgery, gynecology & obstetrics. (1983) [Pubmed]
  15. Asymptomatic rhabdomyolysis of unknown etiology. Hagley, M.T., Sorrell, J.H. The Journal of the American Board of Family Practice / American Board of Family Practice. (1990) [Pubmed]
  16. The influence of a brief preoperative illness on postoperative healing. Goodson, W.H., Lopez-Sarmiento, A., Jensen, J.A., West, J., Granja-Mena, L., Chavez-Estrella, J. Ann. Surg. (1987) [Pubmed]
  17. Atrial natriuretic peptide replacement therapy in rats subjected to biatrial appendectomy. Perera, S.A., Frame, R., Brodman, R.F., Zeballos, G.A., Hintze, T.H., Panetta, T.F. J. Thorac. Cardiovasc. Surg. (1995) [Pubmed]
  18. Plasma atrial natriuretic peptide and blood pressure during chronic salt loading in spontaneously hypertensive rats with right atrial appendectomy. Gradin, K., Hedner, J., Hedner, T., Persson, B. J. Neural Transm. (1987) [Pubmed]
  19. A cost effective approach to surgical antibiotic prophylaxis. Pavan, M.M., Malyuk, D.L. The Canadian journal of hospital pharmacy. (1992) [Pubmed]
  20. Role of atrial natriuretic peptide in volume-expansion natriuresis. Schwab, T.R., Edwards, B.S., Heublein, D.M., Burnett, J.C. Am. J. Physiol. (1986) [Pubmed]
  21. MALTectomy (appendectomy/tonsillectomy) does not influence the occurrence or mode of presentation of adult celiac disease. O'Gorman, P., Bennett, D., Kavanagh, E., Twohig, L.B., O'Sullivan, G.C., O'Regan, P., Shanahan, F. Am. J. Gastroenterol. (1996) [Pubmed]
  22. Atrial natriuretic peptide secretion and body fluid balance after bilateral atrial appendectomy by the maze procedure. Yoshihara, F., Nishikimi, T., Kosakai, Y., Isobe, F., Matsuoka, H., Takishita, S., Kawashima, Y., Saito, Y., Matsuo, H., Kangawa, K. J. Thorac. Cardiovasc. Surg. (1998) [Pubmed]
  23. The treatment of complicated appendicitis in children using peritoneal drainage: results from a public hospital. Curran, T.J., Muenchow, S.K. J. Pediatr. Surg. (1993) [Pubmed]
  24. Urea production related to intraperitoneal inflammation. Sorensen, F.H., Boné, J., Skovgaard, N.S. Ann. Surg. (1975) [Pubmed]
  25. Effect of prophylactic antibiotics in acute nonperforated appendicitis: a prospective, randomized, double-blind clinical study. Busuttil, R.W., Davidson, R.K., Fine, M., Tompkins, R.K. Ann. Surg. (1981) [Pubmed]
  26. Concentrations of cefmetazole in plasma and tissue resulting from peri-incisional administration before appendectomy. Rodríguez, J.R., Mariño, E.L., Otero, M.J., Commes, J.R., Garcia, J., Rodriguez, J.M., Lozano, F., Dominguez-Gil, A., Alonso, A.G. Antimicrob. Agents Chemother. (1984) [Pubmed]
  27. Concentrations of serotonin in plasma--a test for appendicitis? Singh, S.M., Dean, H.G., de Dombal, F.T., Wilson, D.H., Flowers, M.W. Clin. Chem. (1988) [Pubmed]
  28. Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy. Carmine, A.A., Brogden, R.N., Heel, R.C., Speight, T.M., Avery, G.S. Drugs (1982) [Pubmed]
  29. Genetic and environmental factors in monozygotic twins with Crohn's disease and their first-degree relatives: a case report. Vind, I., Jespersgaard, C., Hougs, L., Riis, L., Dinesen, L., Andersen, P.S., Locht, H., Jess, T., Munkholm, P. Digestion (2005) [Pubmed]
  30. Spinal anesthesia in MELAS syndrome: a case with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes. Hsiao, P.N., Cheng, Y.J., Tseng, H.C., Chuang, Y.H., Kao, P.F., Tsai, S.K. Acta Anaesthesiol. Sin. (2000) [Pubmed]
  31. Temporomandibular disorders: clinical and laboratory analyses for risk assessment of criteria for surgical therapy, a pilot study. Halpern, L.R., Chase, D.C., Gerard, D.A., Behr, M.M., Jacobs, W. Cranio : the journal of craniomandibular practice. (1998) [Pubmed]
  32. Atrial natriuretic factor release during angiotensin II infusion in right and left atrial appendectomized rats. Lachance, D., Garcia, R. J. Hypertens. (1989) [Pubmed]
  33. Effects of halothane, enflurane, and nitrous oxide on oxyhemoglobin affinity. Lanza, V., Mercadante, S., Pignataro, A. Anesthesiology (1988) [Pubmed]
  34. Influence of parenteral nutrition on postoperative recovery in an experimental model of peritonitis. Sitges-Serra, A., Hernández, R., Maestro, S., Fernández, N., Girvent, M., Sancho, J.J. Clinical nutrition (Edinburgh, Scotland) (2001) [Pubmed]
  35. Intraincisional antibiotics in laparotomy wounds. Moesgaard, F., Lykkegaard-Nielsen, M., Justesen, T. Dis. Colon Rectum (1984) [Pubmed]
  36. Influence of antecedent lymphoid surgery on the odds of acquiring rheumatoid arthritis. Fernandez-Madrid, F., Reed, A.H., Karvonen, R.L., Granda, J.L. J. Rheumatol. (1985) [Pubmed]
  37. The effect of tonsillectomy and appendectomy on the development of rheumatoid arthritis. Linos, A.D., O'Fallon, W.M., Worthington, J.W., Kurland, L.T. J. Rheumatol. (1986) [Pubmed]
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