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Disease relevance of Cholecystectomy


High impact information on Cholecystectomy

  • We studied the effects of specific inhibition of cholesterol synthesis by one of these agents (pravastatin) on the hepatic metabolism of cholesterol in patients with gallstone disease who were scheduled to undergo cholecystectomy [6].
  • Ten patients were treated with pravastatin (20 mg twice a day) for three weeks before cholecystectomy; 20 patients not treated served as controls [6].
  • Ninety-six of 683 patients undergoing cholecystectomy at the Naval Regional Medical Center, Long Beach, Calif, from 1967 to 1974 were between 7 and 25 years old [7].
  • In 11 cholecystectomy patients (otherwise healthy) lipolytic ED50 for beta agonists correlated in omental and subcutaneous fat cells (r = 0.85 for isoprenaline; r = 0.95 for terbutaline) [8].
  • After cholecystectomy, concentration and output of bile acids relative to bilirubin increased (P less than 0.02) in fasting duodenal bile and cholesterol saturation decreased by 27% (P less than 0.05) consistent with enhanced enterohepatic cycling of bile acids [9].

Chemical compound and disease context of Cholecystectomy


Biological context of Cholecystectomy


Anatomical context of Cholecystectomy


Associations of Cholecystectomy with chemical compounds


Gene context of Cholecystectomy


Analytical, diagnostic and therapeutic context of Cholecystectomy


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  10. Portal venous bile acids in cholesterol gallstone disease: effect of treatment with chenodeoxycholic and cholic acids. Einarsson, K., Ahlberg, J., Angelin, B., Björkhem, I., Ewerth, S. Hepatology (1985) [Pubmed]
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  16. Increased oxidoreduction of deoxycholic acid in cholecystectomised patients. Einarsson, K., Nilsell, K., Björkhem, I. Gut (1989) [Pubmed]
  17. Intraoperative ceforanide pharmacokinetics and protein binding. DiPiro, J.T., Bayoumi, S.M., Vallner, J.J., Nesbit, R.R., Gokhale, R., Rissing, J.P. Antimicrob. Agents Chemother. (1985) [Pubmed]
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  23. Enterohepatic circulation of bile acids after cholecystectomy. Roda, E., Aldini, R., Mazzella, G., Roda, A., Sama, C., Festi, D., Barbara, L. Gut (1978) [Pubmed]
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  36. Effect of digoxin on global respiratory muscle strength after cholecystectomy: a double blind study. Siafakas, N.M., Stathopoulou, M., Tzanakis, N., Mitrouska, I., Tsoumakidou, M., Georgopoulos, D. Thorax (2000) [Pubmed]
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