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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Tumor Stem Cells

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Disease relevance of Tumor Stem Cells


High impact information on Tumor Stem Cells


Biological context of Tumor Stem Cells


Anatomical context of Tumor Stem Cells


Associations of Tumor Stem Cells with chemical compounds


Gene context of Tumor Stem Cells

  • Future studies will explore the possible role of ABCG2 in tumor stem cells and how this may influence the selection of new cancer therapeutic strategies [16].
  • Although instability could not be eliminated as a contributing factor, IFN-beta had significantly less growth inhibitory potency for cells from ovarian cancers when compared simultaneously with native IFN-alpha in the human tumor stem cell assay (HTSCA) [17].
  • The antitumor activity of tumor necrosis factor (TNF) against various primarily cultured human cancer cells (32 cases) was investigated by the 51Cr cytotoxic release assay and the tumor stem cell assay [18].
  • CONCLUSION: Our results provide evidence that the majority of Schwannian and neuroblastic cells in stage 4 NB are of neoplastic origin, and support the hypothesis of a tumor stem cell capable of development along multiple lineages [19].
  • We investigated the effects and interactions of epidermal growth factor (EGF), insulin, hydrocortisone, and estradiol on the growth of 18 freshly obtained human tumors in our human tumor stem cell assay (HTSCA) cultured at a reduced serum concentration (8.5% ml) [20].


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  15. Antitumor activity of didemnin B in the human tumor stem cell assay. Jiang, T.L., Liu, R.H., Salmon, S.E. Cancer Chemother. Pharmacol. (1983) [Pubmed]
  16. ABCG2 (BCRP): a cytoprotectant in normal and malignant stem cells. Abbott, B.L. Clinical advances in hematology & oncology : H&O (2006) [Pubmed]
  17. Antiproliferative activity of human interferons against ovarian cancer cells grown in human tumor stem cell assay. Willson, J.K., Bittner, G., Borden, E.C. J. Interferon Res. (1984) [Pubmed]
  18. Antitumor effect of tumor necrosis factor against various primarily cultured human cancer cells. Watanabe, N., Niitsu, Y., Neda, H., Sone, H., Yamauchi, N., Umetsu, T., Urushizaki, I. Jpn. J. Cancer Res. (1985) [Pubmed]
  19. Laser-capture microdissected schwannian and neuroblastic cells in stage 4 neuroblastomas have the same genetic alterations. Mora, J., Akram, M., Cheung, N.K., Chen, L., Gerald, W.L. Med. Pediatr. Oncol. (2000) [Pubmed]
  20. Effects and interactions of epidermal growth factor, insulin, hydrocortisone, and estradiol on the cloning of human tumor cells. Singletary, S.E., Tomasovic, B., Spitzer, G., Tucker, S.L., Hug, V., Drewinko, B. Int. J. Cell Cloning (1985) [Pubmed]
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