Disease relevance of Vesico-Ureteral Reflux

• This study reports the effects of 3-weeks' antimicrobial treatment on the pathology and appearance of the 99mTc-DMSA renal image in piglets with pyelonephritis induced by a combination of vesicoureteral reflux (VUR) and urinary infection [1].
• Submucosal injections of polytetrafluoroethylene (PTFE) and polydimethylsiloxane (PDMS) paste continue to be used for the correction of vesicoureteral reflux and urinary incontinence [2].
• It appears that the presence of vesico-ureteral reflux with or without associated hydroureter and hydronephrosis is a prerequisite for cyclophosphamide-induced renal damage [3].
• Rats were treated transperitoneally with cyclophosphamide (200 mg/kg) to induce leukopenia 3 days before and transurethrally with diluted acetic acid solution to induce vesicoureteral reflux 1 day before inoculation of Candida albicans strain, ATCC 10259 (containing 10(7) cells) [4].

High impact information on Vesico-Ureteral Reflux

• Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux [5].
• OBJECTIVES: Dextranomer/hyaluronic acid (Dx/HA) copolymer has favorable properties for endoscopic treatment of vesico-ureteral reflux (VUR) [6].
• Dextranomer/hyaluronic acid copolymer implantation for vesico-ureteral reflux: a randomized comparison with antibiotic prophylaxis [6].
• Five-year study of medical or surgical treatment in children with severe vesico-ureteral reflux. Dimercaptosuccinic acid findings [7].
• CONCLUSIONS: High grade vesicoureteral reflux is associated with ureteropelvic junction obstruction [8].

Chemical compound and disease context of Vesico-Ureteral Reflux

• Re: Evaluation of polydimethylsiloxane as an alternative in the endoscopic treatment of vesicoureteral reflux [9].
• These data suggest that prednisolone is effective in preventing renal scarring which occurs due to vesicoureteral reflux when the initiation of antimicrobial treatment is delayed [10].
• These preliminary results indicate that polyvinyl alcohol foam may be suitable for subureteral injection in the treatment of vesicoureteral reflux [11].
• After injection of levcromakalim (0.3 mg/kg, i.v.), vesicoureteral reflux did not occur [12].
• Serum electrolyte equilibrium and plasma aldosterone concentrations were monitored in 19 infants who had severe obstructive uropathy or grade 5 vesico-ureteral reflux and were undergoing surgical correction in the first 2 months of life [13].

Anatomical context of Vesico-Ureteral Reflux

• The aim of this study was to present current theories of pathogenesis and prognosis in urinary tract infection (UTI) and renal scarring during infancy and childhood, with special regard to new insights concerning the role of vesico-ureteral reflux (VUR) [14].
• MATERIALS AND METHODS: 498 children with vesico-ureteral reflux (VUR) were observed in 702 ureters [15].

Gene context of Vesico-Ureteral Reflux

• PUJO was also observed in a maternal uncle, whose daughter suffered from vesico-ureteral reflux (VUR) [16].
• Therefore, GAX 65 will most probably prove to be an excellent substance for the endoscopic treatment of vesicoureteral reflux and incontinence in children [17].

References