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Chemical Compound Review

99Tc-Succimer     2,3-bis-sulfanylbutanedioic acid; technetium

Synonyms: AC1L2ABP, D02025, 99mTc-Dmsa, UNII-494JNQ8L28, Technetium-succimer, ...
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Disease relevance of Dimercaptosuccinic acid


High impact information on Dimercaptosuccinic acid


Chemical compound and disease context of Dimercaptosuccinic acid


Biological context of Dimercaptosuccinic acid


Anatomical context of Dimercaptosuccinic acid


Associations of Dimercaptosuccinic acid with other chemical compounds


Gene context of Dimercaptosuccinic acid


Analytical, diagnostic and therapeutic context of Dimercaptosuccinic acid


  1. Quantitative analysis of 99mTc-DMSA during acute pyelonephritis for prediction of long-term renal scarring. Hitzel, A., Liard, A., Dacher, J.N., Gardin, I., Ménard, J.F., Manrique, A., Véra, P. J. Nucl. Med. (2004) [Pubmed]
  2. Differentiating histologic malignancy of primary brain tumors: pentavalent technetium-99m-DMSA. Hirano, T., Otake, H., Shibasaki, T., Tamura, M., Endo, K. J. Nucl. Med. (1997) [Pubmed]
  3. Schwannoma of the extremities: comparison of MRI and pentavalent technetium-99m-dimercaptosuccinic acid and gallium-67-citrate scintigraphy. Kobayashi, H., Kotoura, Y., Sakahara, H., Hosono, M., Hosono, M., Tsaboyama, T., Yamamuro, T., Endo, K., Konishi, J. J. Nucl. Med. (1994) [Pubmed]
  4. Quantitative SPECT of technetium-99m-DMSA uptake in the kidneys of normal children and in kidneys with vesicoureteral reflux: detection of unilateral kidney disease. Groshar, D., Moskovitz, B., Gorenberg, M., Frankel, A., Jerusalmi, J., Livne, P.M., Front, D. J. Nucl. Med. (1994) [Pubmed]
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  6. Renal cortical scintigraphy and diuresis renography in infants and children. Rossleigh, M.A. J. Nucl. Med. (2001) [Pubmed]
  7. Renal fibrosis: prediction from acute pyelonephritis focus volume measured at 99mTc dimercaptosuccinic acid SPECT. Chiou, Y.Y., Wang, S.T., Tang, M.J., Lee, B.F., Chiu, N.T. Radiology. (2001) [Pubmed]
  8. Reproducibility of renal length measurements with 99mTc-DMSA SPECT. Lin, E., Connolly, L.P., Zurakowski, D., DiCanzio, J., Drubach, L., Mitchell, K., Tetrault, T., Laffin, S.P., Treves, S.T. J. Nucl. Med. (2000) [Pubmed]
  9. Increased urine interleukin-6 concentrations correlate with pyelonephritic changes on 99mTc-dimercaptosuccinic acid scans in neonates with urinary tract infections. Roilides, E., Papachristou, F., Gioulekas, E., Tsaparidou, S., Karatzas, N., Sotiriou, J., Tsiouris, J. J. Infect. Dis. (1999) [Pubmed]
  10. Renal function after tumor enucleation: assessment by quantitative SPECT of 99mTc-dimercaptosuccinic acid uptake by the kidneys. Groshar, D., Moskovitz, B., Kastin, A., Issaq, E., Nativ, O. J. Nucl. Med. (1999) [Pubmed]
  11. Quantitative 99mTc-DMSA uptake in experimental pyelonephritis. Godley, M.L., Risdon, R.A., Gordon, I., Parkhouse, H.F., Ransley, P.G. J. Nucl. Med. (1999) [Pubmed]
  12. Technetium-99m dimercaptosuccinic acid and ifosfamide tubular dysfunction in children with cancer. Anninga, J.K., Valdés Olmos, R.A., de Kraker, J., van Tinteren, H., Hoefnagel, C.A., van Royen, E.A. European journal of nuclear medicine. (1994) [Pubmed]
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  14. Delayed scanning with DMSA: a simple index of relative renal plasma flow. Taylor, A. Radiology. (1980) [Pubmed]
  15. Tubular reabsorption of technetium-99m-DMSA. Müller-Suur, R., Gutsche, H.U. J. Nucl. Med. (1995) [Pubmed]
  16. Low renal uptake of 99mTc-DMSA in patients with proximal tubular dysfunction. van Luÿk, W.H., Ensing, G.J., Piers, D.A. European journal of nuclear medicine. (1983) [Pubmed]
  17. Reversible diminished renal 99mTc-DMSA uptake during converting-enzyme inhibition in a patient with renal artery stenosis. Hovinga, T.K., Beukhof, J.R., van Luyk, W.H., Piers, D.A., Donker, A.J. European journal of nuclear medicine. (1984) [Pubmed]
  18. Escherichia coli virulence factors and 99mTc-dimercaptosuccinic acid renal scan in children with febrile urinary tract infection. Jantausch, B.A., Wiedermann, B.L., Hull, S.I., Nowicki, B., Getson, P.R., Rushton, H.G., Majd, M., Luban, N.L., Rodriguez, W.J. Pediatr. Infect. Dis. J. (1992) [Pubmed]
  19. Hypoplastic dysplastic kidney with a vaginal ectopic ureter identified by technetium-99m-DMSA scintigraphy. Bozorgi, F., Connolly, L.P., Bauer, S.B., Neish, A.S., Tan, P.E., Schofield, D., Treves, S.T. J. Nucl. Med. (1998) [Pubmed]
  20. Indium-111-DTPA-D-Phe-1-octreotide and technetium-99m-(V)-dimercaptosuccinic acid scanning in the preoperative staging of medullary thyroid carcinoma. Kurtaran, A., Scheuba, C., Kaserer, K., Schima, W., Czerny, C., Angelberger, P., Niederle, B., Virgolini, I. J. Nucl. Med. (1998) [Pubmed]
  21. Renal artery stenosis and hypertension after abdominal irradiation for Hodgkin disease. Successful treatment with nephrectomy. Salvi, S., Green, D.M., Brecher, M.L., Magoos, I., Gamboa, L.N., Fisher, J.E., Baliah, T., Afshani, E. Urology (1983) [Pubmed]
  22. Is the relative 99mTc-DMSA clearance a useful marker of proximal tubular dysfunction? van Luijk, W.H., Ensing, G.J., Meijer, S., Donker, A.J., Piers, D.A. European journal of nuclear medicine. (1984) [Pubmed]
  23. Technetium-99m-L,L-ethylenedicysteine renal scan as a single-modality investigation for the evaluation of renal morphology and function: a comparative study with technetium-99m-dimercaptosuccinic acid. Narayana, C., Tripathi, M., Kumar, A., Gowda, N.K., Phom, H., Chandra, P., Bandopadhyaya, G., Bal, C. Nuclear medicine communications. (2004) [Pubmed]
  24. Vesicoureteric reflux and renal scars in asymptomatic siblings of children with reflux. Kenda, R.B., Fettich, J.J. Arch. Dis. Child. (1992) [Pubmed]
  25. Urine interleukin-6 and interleukin-8 in children with acute pyelonephritis, in relation to DMSA scintigraphy in the acute phase and at 1-year follow-up. Tullus, K., Fituri, O., Linné, T., Escobar-Billing, R., Wikstad, I., Karlsson, A., Burman, L.G., Wretlind, B., Brauner, A. Pediatric radiology. (1994) [Pubmed]
  26. Model to evaluate the toxic effect of drugs: vincristine effect in the mass of organs and in the distribution of radiopharmaceuticals in mice. Mattos, D.M., Gomes, M.L., Freitas, R.S., Bernardo-Filho, M. Mutat. Res. (2001) [Pubmed]
  27. Renal radiopharmaceuticals--an update. Chervu, L.R., Blaufox, M.D. Seminars in nuclear medicine. (1982) [Pubmed]
  28. The use of imaging studies in the diagnosis and management of thyroid cancer and hyperparathyroidism. James, C., Starks, M., MacGillivray, D.C., White, J. Surg. Oncol. Clin. N. Am. (1999) [Pubmed]
  29. The role of 99mTc DMSA renal scintigraphy in Joubert syndrome. Kara Gedik, G., Lay Ergün, E., Fani Bozkurt, M. Revista española de medicina nuclear. (2006) [Pubmed]
  30. Posterior 180 degrees 99mTc-dimercaptosuccinic acid renal SPECT. Peng, N.J., Kwok, C.G., Chiou, Y.H., Jao, G.H., Tsay, D.G., Liu, R.S., Strauss, H.W. J. Nucl. Med. (1999) [Pubmed]
  31. Interobserver reproducibility in reporting on 99mTc-DMSA scintigraphy for detection of late renal sequelae. Ladron De Guevara, D., Franken, P., De Sadeleer, C., Ham, H., Piepsz, A. J. Nucl. Med. (2001) [Pubmed]
  32. Radiation dosimetry of technetium-99m-DMSA in children. Smith, T., Evans, K., Lythgoe, M.F., Anderson, P.J., Gordon, I. J. Nucl. Med. (1996) [Pubmed]
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