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Chemical Compound Review

Polyviol     ethenol

Synonyms: Gelvatol, Gohsenol, Vinarole, alkenols, Alkotex, ...
 
 
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Disease relevance of POLYVINYL ALCOHOL

 

Psychiatry related information on POLYVINYL ALCOHOL

 

High impact information on POLYVINYL ALCOHOL

 

Chemical compound and disease context of POLYVINYL ALCOHOL

 

Biological context of POLYVINYL ALCOHOL

 

Anatomical context of POLYVINYL ALCOHOL

 

Associations of POLYVINYL ALCOHOL with other chemical compounds

  • Further comparisons suggest that resonance effects are between roughly 58% and 65% of the 26 kcal/mol calculated acidity enhancement of vinyl alcohol over methanol, and the remaining 42% to 35% are due to inductive effects [27].
  • Based on the results of in vitro and in vivo experiments, we have determined that the optimal material for the central transparent portion of a perforating keratoprosthesis is a polyvinyl alcohol copolymer hydrogel [28].
  • Segmental and complete hepatic artery embolization with Ivalon (polyvinyl alcohol) particles (0.25 to 1 mm) was performed in 12 dogs to evaluate hepatic function alterations and histopathological changes [25].
  • With PVA, a large amount of capillary formations occurred within the embolized arteries, whereas chitin particles and chitosan microspheres showed a lower rate of capillary formation [26].
  • On-chip capillary electrophoresis with uncoated and polyvinyl alcohol-coated glass channels in aqueous and nonaqueous dimethyl sulfoxide (DMSO) background electrolyte (BGE) solutions was applied in the separation of five amines derivatized with fluorescein-5-isothiocyanate [29].
 

Gene context of POLYVINYL ALCOHOL

  • An inhibitor, OM00-3, Glu-Leu-Asp-LeuAla-Val-Glu-Phe (where the asterisk represents the hydroxyethylene tansition-state isostere), designed from the consensus residues, was found to be the most potent inhibitor of memapsin 2 so far reported (K(i) of 3.1 x 10(-10) M) [30].
  • We have previously shown that angiogenesis, as reflected by fibrovascular invasion into subcutaneously implanted polyvinyl alcohol (PVA) sponges, is increased in SPARC-null mice (6-9 months of age) relative to their wild-type (WT) counterparts [31].
  • SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges [32].
  • To study the effects of insulin and insulin-like growth factor-I (IGF-I) on the development of bovine embryos, fertilized bovine embryos in vitro were cultured in a chemically defined, protein-free medium: modified synthetic oviduct fluid (mSOF) supplemented with lmg/ml polyvinyl alcohol [33].
  • The first potent inhibitors are based on the sequence of APP around the beta-secretase cleavage site EVNL/DAEF, with the scissile Leu-Asp amide bond being replaced by a hydroxyethylene transition state analogue isostere [34].
 

Analytical, diagnostic and therapeutic context of POLYVINYL ALCOHOL

References

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  22. Suppression of the anti-DNP IgE response with tolerogenic conjugates of DNP with polyvinyl alcohol. II. Induction of hapten-specific suppressor T cells. Lee, W.Y., Sehon, A.H. J. Immunol. (1981) [Pubmed]
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  29. Separation of fluorescein isothiocyanate-labeled amines by microchip electrophoresis in uncoated and polyvinyl alcohol-coated glass chips using water and dimethyl sulfoxide as solvents of background electrolyte. Varjo, S.J., Ludwig, M., Belder, D., Riekkola, M.L. Electrophoresis (2004) [Pubmed]
  30. Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design. Turner, R.T., Koelsch, G., Hong, L., Castanheira, P., Ermolieff, J., Ghosh, A.K., Tang, J., Castenheira, P., Ghosh, A. Biochemistry (2001) [Pubmed]
  31. Enhanced angiogenesis characteristic of SPARC-null mice disappears with age. Reed, M.J., Bradshaw, A.D., Shaw, M., Sadoun, E., Han, N., Ferara, N., Funk, S., Puolakkainen, P., Sage, E.H. J. Cell. Physiol. (2005) [Pubmed]
  32. SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges. Puolakkainen, P.A., Bradshaw, A.D., Brekken, R.A., Reed, M.J., Kyriakides, T., Funk, S.E., Gooden, M.D., Vernon, R.B., Wight, T.N., Bornstein, P., Sage, E.H. J. Histochem. Cytochem. (2005) [Pubmed]
  33. Stimulation of the development of bovine embryos by insulin and insulin-like growth factor-I (IGF-I) is mediated through the IGF-I receptor. Matsui, M., Takahashi, Y., Hishinuma, M., Kanagawa, H. Theriogenology (1997) [Pubmed]
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  36. Midterm results of uterine artery embolization for symptomatic adenomyosis: initial experience. Pelage, J.P., Jacob, D., Fazel, A., Namur, J., Laurent, A., Rymer, R., Le Dref, O. Radiology. (2005) [Pubmed]
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