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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Immunization Schedule

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Disease relevance of Immunization Schedule


High impact information on Immunization Schedule

  • We have also shown the effectiveness of oral delivery by using a parenteral prime-oral boost immunization schedule [6].
  • Spleen cells from rat erythrocyte-immunized mice, when transferred to syngeneic recipients undergoing similar immunization schedules, delayed the appearance of erythrocyte autoantibodies in the recipients [7].
  • The delivery of IL-12 and Env product during priming with a DNA vector, followed by a booster with VV expressing the Env gene (rVVenv), was found to trigger the optimal CMI response compared with other immunization schedules studied [8].
  • In a second experiment involving two groups (FIVDeltaRT plus IFN-gamma and IFN-gamma alone), the immunization schedule was reduced to 0, 4, and 8 weeks [9].
  • The newly developed Tg PVR mouse-protection test may be useful in evaluating existing IPV potency tests and for attempts to improve formulations of trivalent IPV or combined vaccines for childhood immunization schedules [10].

Biological context of Immunization Schedule

  • In summary, the LHRH fusion proteins were as effective as surgical spaying in suppression of estrous cycle activity, but alternating the two proteins in an immunization schedule did not enhance the immunological or biological effectiveness of the vaccine [11].

Associations of Immunization Schedule with chemical compounds


Gene context of Immunization Schedule

  • The latter is the basis for the adoption of a two-dose measles immunization schedule by the ACIP and AAP [17].
  • The immunization schedules using CW preparation caused a preferential production of IgM and IgG3 antibodies [18].
  • The highest anti-GST-Nef titers were obtained by a third immunization schedule in which mice were treated with a priming inoculum of induced live vaccine followed, after the predicted immunosuppressed interval, by two i.p. doses of 1 microgram of purified GST-Nef protein with Ribi adjuvant [19].
  • This study was carried out with sera from mice and hamsters submitted to different immunization schedules: chronic administration of the antigen, secondary response and conventional hyperimmunization [20].
  • Our data therefore provide the basis for optimized immunization schedules with TDM as the adjuvant component of a Th1 vaccine [21].

Analytical, diagnostic and therapeutic context of Immunization Schedule


  1. Effect of dose and immunization schedule on immune response of baboons to recombinant glycoprotein 120 of HIV-1. Anderson, K.P., Lucas, C., Hanson, C.V., Londe, H.F., Izu, A., Gregory, T., Ammann, A., Berman, P.W., Eichberg, J.W. J. Infect. Dis. (1989) [Pubmed]
  2. Susceptibility to and escape from complement-mediated lysis of guinea-pig hepatoma line-10. Abe, S., Berczi, I., Sehon, A.H. Int. J. Cancer (1977) [Pubmed]
  3. Coronavirus-induced encephalomyelitis: balance between protection and immune pathology depends on the immunization schedule with spike protein S. Flory, E., Stühler, A., Barac-Latas, V., Lassmann, H., Wege, H. J. Gen. Virol. (1995) [Pubmed]
  4. Anaphylactic bronchoconstriction in rats immunized with antigen-coated latex particles. Eady, R.P., Trigg, S., Orr, T.S. Clin. Exp. Immunol. (1978) [Pubmed]
  5. The efficacy of DPT and oral poliomyelitis immunization schedules initiated from birth to 12 weeks of age. Halsey, N., Galazka, A. Bull. World Health Organ. (1985) [Pubmed]
  6. Oral immunization with hepatitis B surface antigen expressed in transgenic plants. Kong, Q., Richter, L., Yang, Y.F., Arntzen, C.J., Mason, H.S., Thanavala, Y. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  7. Effect of thymopoietin pentapeptide (TP5) on autoimmunity. I. TP5 suppression of induced erythrocyte autoantibodies in C3H mice. Lau, C.Y., Freestone, J.A., Goldstein, G. J. Immunol. (1980) [Pubmed]
  8. Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediated by nitric oxide. Gherardi, M.M., Ramírez, J.C., Esteban, M. J. Virol. (2000) [Pubmed]
  9. DNA vaccination affords significant protection against feline immunodeficiency virus infection without inducing detectable antiviral antibodies. Hosie, M.J., Flynn, J.N., Rigby, M.A., Cannon, C., Dunsford, T., Mackay, N.A., Argyle, D., Willett, B.J., Miyazawa, T., Onions, D.E., Jarrett, O., Neil, J.C. J. Virol. (1998) [Pubmed]
  10. Inactivated poliovirus vaccine protects transgenic poliovirus receptor mice against type 3 poliovirus challenge. Taffs, R.E., Chernokhvostova, Y.V., Dragunsky, E.M., Nomura, T., Hioki, K., Beuvery, E.C., Fitzgerald, E.A., Levenbook, I.S., Asher, D.M. J. Infect. Dis. (1997) [Pubmed]
  11. Luteinizing hormone-releasing hormone fusion protein vaccines block estrous cycle activity in beef heifers. Stevens, J.D., Sosa, J.M., deAvila, D.M., Oatley, J.M., Bertrand, K.P., Gaskins, C.T., Reeves, J.J. J. Anim. Sci. (2005) [Pubmed]
  12. Induction of humoral immunity toward 2-acetylaminofluorene in mice: modulation of DNA binding after 4 weeks dietary exposure to the carcinogen. Verdina, A., Zito, R., Cortese, G., Leopardi, P., Marcon, F., Zijno, A., Crebelli, R. Carcinogenesis (1996) [Pubmed]
  13. Suppression of local intestinal immunoglobulin A immune response to cholera toxin by subcutaneous administration of cholera toxoids. Hamilton, S.R., Yardley, J.H., Brown, G.D. Infect. Immun. (1979) [Pubmed]
  14. In vivo cimetidine immunomodulatory effects on the cutaneous reaction to oxazolone in the chicken. Bellavia, A., Bannera, A.F., Marino, V., Arcoleo, V., Ferrara, D. Immunopharmacology (1997) [Pubmed]
  15. Immunogenicity of a polyvalent melanoma antigen vaccine in humans. Bystryn, J.C., Oratz, R., Harris, M.N., Roses, D.F., Golomb, F.M., Speyer, J.L. Cancer (1988) [Pubmed]
  16. Studies on the optimal immunization schedule of experimental animals. VI. Antigen dose-response of aluminum hydroxide-aided immunization and booster effect under low antigen dose. Hu, J.G., Kitagawa, T. Chem. Pharm. Bull. (1990) [Pubmed]
  17. A new look at measles. Adcock, L.M., Bissey, J.D., Feigin, R.D. Infect. Dis. Clin. North Am. (1992) [Pubmed]
  18. The role of somatic structure of the fungus Paracoccidioides brasiliensis upon B cell activation in experimental paracoccidioidomycosis. Silva, M.F., Silva, C.L. Clin. Exp. Immunol. (1995) [Pubmed]
  19. Immunogenicity of Nef protein of SIVSMM-PBj14 expressed in a live vaccine strain of Salmonella species. Cattozzo, E.M., Stocker, B.A. AIDS Res. Hum. Retroviruses (1994) [Pubmed]
  20. Stochastic humoral expression of human growth hormone epitopes. Etcheverrigaray, M., Paladini, A.C., Retegui, L.A. Immunology (1988) [Pubmed]
  21. Mycobacterial cord factor, but not sulfolipid, causes depletion of NKT cells and upregulation of CD1d1 on murine macrophages. Ryll, R., Watanabe, K., Fujiwara, N., Takimoto, H., Hasunuma, R., Kumazawa, Y., Okada, M., Yano, I. Microbes Infect. (2001) [Pubmed]
  22. Impaired antibody response rates after high dose short interval hepatitis B virus vaccination of immunosuppressed individuals. Idilman, R., Colantoni, A., De Maria, N., Ustun, C., Sam, R., Ing, T.S., Akan, H., Koc, H., Van Thiel, D.H. Hepatogastroenterology (2003) [Pubmed]
  23. The hepatitis B immunization campaign for children in the Federated States of Micronesia. Manea, S.J., Iohp, K. Public health reports (Washington, D.C. : 1974) (1992) [Pubmed]
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