Disease relevance of Affective Disorders, Psychotic

• 61 patients - 28 suffering from bipolar, and 33 from unipolar psychotic affective disorders - completed two personality inventories, one before and one about 6 months after starting lithium treatment to prevent relapses [1].

Psychiatry related information on Affective Disorders, Psychotic

• OBJECTIVES: (1) Assessment of diagnostic stability of psychotic disorders or psychotic mood disorders from 6 weeks to 18 months after initiation of treatment in a representative first-episode psychosis (FEP) sample [2].
• RESULTS: Compared with late-middle-aged and older index medical patients (n = 11,701), index mental health patients (n = 9039) were more likely to have affective psychoses and major depressive disorder and less likely to have depressive disorder NOS [3].

High impact information on Affective Disorders, Psychotic

• The skeletal muscle MAO activity of schizophrenics and patients with bipolar and unipolar affective psychoses was lower than that of normal controls [4].
• Serum dopamine-beta-hydroxylase activity in the affective psychoses and schizophrenia. Decreased activity in unipolar psychotically depressed patients [5].
• The use of lithium in the affective psychoses. 1966 [6].
• Psychotic affective disorder after nicotine withdrawal [7].
• P300 amplitude and topography in psychotic affective disorder, a crucial comparison in assessing the specificity of P300 abnormalities to schizophrenia, are not well studied [8].

Chemical compound and disease context of Affective Disorders, Psychotic

• Basal and haloperidol-stimulated prolactin and symptoms of nonaffective and affective psychoses in neuroleptic-free men [9].
• However, little is known about the efficacy of risperidone in patients with schizophrenia refractory to treatment with typical antipsychotics, schizoaffective disorder, and psychotic mood disorders [10].
• Plasma cortisol was increased to a lesser extent in other psychotic subgroups, and increases in prolactin were most marked in the affective psychoses [11].
• The mechanism of the therapeutic and prophylactic effects of carbamazepine (CBZ) in affective psychoses is unknown but may in part be related to the potent competitive interaction of CBZ with adenosine-binding sites in the brain [12].
• Effect of in vivo lithium treatment on (-)isoproterenol-stimulated cAMP accumulation in lymphocytes of healthy subjects and patients with affective psychoses [13].

Biological context of Affective Disorders, Psychotic

• The association between treatment with lithium carbonate and smooth pursuit eye tracking performance was investigated in first-episode patients with psychotic affective disorders [14].

Anatomical context of Affective Disorders, Psychotic

• Schizophrenia and affective psychoses share the following: 1) several treatments are effective in both, 2) similar modes of inheritance, 3) congruent seasonal birth excesses, 4) enlarged cerebral ventricles and cerebellar vermian atrophy, 5) dexamethasone non-suppression [15].

Gene context of Affective Disorders, Psychotic

• Affective psychoses are characterized by an excess of the haptoglobin (Hp) serum type 2-2 (p less than 0.001) [16].
• BACKGROUND: Risperidone, a 5-HT2 and D2 antagonist, has been shown to be an effective antipsychotic in the treatment of schizophrenia but has unclear efficacy in the treatment of psychotic affective disorders [17].
• These studies have focused primarily on schizophrenia, and less so on the affective psychoses, including psychotic major depression PMD [18].
• Data were analyzed as rates per 100000 in the general population, and changes over time in incidence of schizophrenia, paranoia, affective psychoses and drug-induced psychoses (diagnosed according to ICD 9) were recorded [19].
• Homocysteinemia as well as methylenetetrahydrofolate reductase polymorphism are associated with affective psychoses [20].

Analytical, diagnostic and therapeutic context of Affective Disorders, Psychotic

• To further explore the connection between homocysteinemia and affective psychoses, a case-control study examining the C677T and the A1298C variants of methylenetetrahydrofolate reductase was conducted [20].

References