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MeSH Review

Cerebral Ventricles

 
 
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Disease relevance of Cerebral Ventricles

 

Psychiatry related information on Cerebral Ventricles

 

High impact information on Cerebral Ventricles

  • The infusion of either insulin or a small-molecule insulin mimetic in the third cerebral ventricle suppressed glucose production independent of circulating levels of insulin and of other glucoregulatory hormones [11].
  • Injection of angiotensin II (AII) into the cerebral ventricles at doses as low as 1 pmol h-1 results in a marked stimulation of salt and water ingestion in the rat [12].
  • The satiety produced by introduction of food into the intestine can be mimicked by systemic injections of CCK and its analogues-these hormones are also effective when injected into the hypothalamus and the cerebral ventricle [13].
  • This observation supports recent reports of elevated concentrations of norepinephrine in specific brain areas adjacent to the cerebral ventricles of paranoid schizophrenic patients [14].
  • Cholecystokinin octapeptide: continuous picomole injections into the cerebral ventricles of sheep suppress feeding [15].
 

Chemical compound and disease context of Cerebral Ventricles

 

Biological context of Cerebral Ventricles

 

Anatomical context of Cerebral Ventricles

 

Associations of Cerebral Ventricles with chemical compounds

  • Tetrahydropapaveroline (THP), a dopamine-dopaldehyde condensation product, was delivered directly into the cerebral ventricle of rats automatically every 15 minutes for 12 days [30].
  • Stimulation of the region antero-ventral to the third cerebral ventricle (AV3V) by a cholinergic drug, carbachol, and lesions of the AV3V have been demonstrated in previous studies to either augment or decrease sodium excretion, respectively [31].
  • To evaluate a possible physiological role of endogenous substance P (SP) in the control of growth hormone (GH; somatotropin) secretion, a specific antiserum against SP (anti-SP) was injected intraventricularly (3 microliters into the third cerebral ventricle) in unanesthetized unrestrained normal male rats [32].
  • We injected recombinant human IL-1 alpha into the third cerebral ventricle, to study its effect on the pulsatile release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in conscious, freely moving, ovariectomized rats [33].
  • Oxytocin (OXT) and [pGlu4,Cyt6]OXT-(4-8) have the opposite effect and attenuate passive avoidance behavior also when administered into the cerebral ventricle after the learning trial [34].
 

Gene context of Cerebral Ventricles

 

Analytical, diagnostic and therapeutic context of Cerebral Ventricles

References

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  33. Interleukin 1 alpha inhibits prostaglandin E2 release to suppress pulsatile release of luteinizing hormone but not follicle-stimulating hormone. Rettori, V., Gimeno, M.F., Karara, A., Gonzalez, M.C., McCann, S.M. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
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