Gene Review:
Sptan1 - spectrin alpha, non-erythrocytic 1
Mus musculus
Synonyms:
2610027H02Rik, Alpha-II spectrin, Fodrin alpha chain, Spectrin alpha chain, non-erythrocytic 1, Spna-2, ...
- Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjögren's syndrome. Saegusa, K., Ishimaru, N., Yanagi, K., Mishima, K., Arakaki, R., Suda, T., Saito, I., Hayashi, Y. J. Immunol. (2002)
- HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Kaul, M., Ma, Q., Medders, K.E., Desai, M.K., Lipton, S.A. Cell Death Differ. (2007)
- HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity. Clement, V., Sanchez, P., de Tribolet, N., Radovanovic, I., Ruiz I Altaba, A. Curr. Biol. (2007)
- Molecular analysis of the human autoantibody response to alpha-fodrin in Sjögren's syndrome reveals novel apoptosis-induced specificity. Maruyama, T., Saito, I., Hayashi, Y., Kompfner, E., Fox, R.I., Burton, D.R., Ditzel, H.J. Am. J. Pathol. (2004)
- MyD88-Dependent Signals Are Essential for the Host Immune Response in Experimental Brain Abscess. Kielian, T., Phulwani, N.K., Esen, N., Syed, M.M., Haney, A.C., McCastlain, K., Johnson, J. J. Immunol. (2007)
- A quantitative, theoretical framework for understanding mammalian sleep. Savage, V.M., West, G.B. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Plexin B3 is genetically associated with verbal performance and white matter volume in human brain. Rujescu, D., Meisenzahl, E.M., Krejcova, S., Giegling, I., Zetzsche, T., Reiser, M., Born, C.M., Möller, H.J., Veske, A., Gal, A., Finckh, U. Mol. Psychiatry (2007)
- Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo. Brijbassi, S., Amtul, Z., Newbigging, S., Westaway, D., St George-Hyslop, P., Rozmahel, R.F. Neurobiol. Dis. (2007)
- Oxidative damage in nucleic acids and Parkinson's disease. Nakabeppu, Y., Tsuchimoto, D., Yamaguchi, H., Sakumi, K. J. Neurosci. Res. (2007)
- Mouse and rat BDNF gene structure and expression revisited. Aid, T., Kazantseva, A., Piirsoo, M., Palm, K., Timmusk, T. J. Neurosci. Res. (2007)
- Identification of alpha-fodrin as a candidate autoantigen in primary Sjögren's syndrome. Haneji, N., Nakamura, T., Takio, K., Yanagi, K., Higashiyama, H., Saito, I., Noji, S., Sugino, H., Hayashi, Y. Science (1997)
- Hair Bundles Are Specialized for ATP Delivery via Creatine Kinase. Shin, J.B., Streijger, F., Beynon, A., Peters, T., Gadzala, L., McMillen, D., Bystrom, C., Van der Zee, C.E., Wallimann, T., Gillespie, P.G. Neuron (2007)
- Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. Ren, D., Zhou, Y., Morris, D., Li, M., Li, Z., Rui, L. J. Clin. Invest. (2007)
- Induction of apoptosis by the transcription factor c-Jun. Bossy-Wetzel, E., Bakiri, L., Yaniv, M. EMBO J. (1997)
- Prefrontal/accumbal catecholamine system determines motivational salience attribution to both reward- and aversion-related stimuli. Ventura, R., Morrone, C., Puglisi-Allegra, S. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Gender and estrogen manipulation do not affect traumatic brain injury in mice. Bruce-Keller, A.J., Dimayuga, F.O., Reed, J.L., Wang, C., Angers, R., Wilson, M.E., Dimayuga, V.M., Scheff, S.W. J. Neurotrauma (2007)
- PCR-Based Diagnosis of Naegleria sp. Infection in Formalin-Fixed and Paraffin-Embedded Brain Sections. Schild, M., Gianinazzi, C., Gottstein, B., Müller, N. J. Clin. Microbiol. (2007)
- Oxidized phosphatidylcholine is a marker for neuroinflammation in multiple sclerosis brain. Qin, J., Goswami, R., Balabanov, R., Dawson, G. J. Neurosci. Res. (2007)
- Seizure prophylaxis in an animal model of epilepsy by dietary fluoxetine supplementation. Richman, A., Heinrichs, S.C. Epilepsy Res. (2007)
- Attenuated function and expression of P-glycoprotein at blood-brain barrier and increased brain distribution of phenobarbital in streptozotocin-induced diabetic mice. Liu, H., Zhang, D., Xu, X., Liu, X., Wang, G., Xie, L., Pang, X., Liu, L. Eur. J. Pharmacol. (2007)
- Mouse IL-1 receptor antagonist protein. Molecular characterization, gene mapping, and expression of mRNA in vitro and in vivo. Zahedi, K., Seldin, M.F., Rits, M., Ezekowitz, R.A., Whitehead, A.S. J. Immunol. (1991)
- Urogenital syndrome (us): a developmental mutation on chromosome 2 of the mouse. Lane, P.W., Birkenmeier, C.S. Mamm. Genome (1993)
- Cloning and deletion mutagenesis using direct protein-protein interaction on an expression vector. Identification of the calmodulin binding domain of alpha-fodrin. Sri Widada, J., Asselin, J., Colote, S., Marti, J., Ferraz, C., Travé, G., Haiech, J., Liautard, J.P. J. Mol. Biol. (1989)
- Controlled expression of transgenes introduced by in vivo electroporation. Matsuda, T., Cepko, C.L. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice. Laposa, R.R., Huang, E.J., Cleaver, J.E. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Na,K-ATPase in skeletal muscle: two populations of beta-spectrin control localization in the sarcolemma but not partitioning between the sarcolemma and the transverse tubules. Williams, M.W., Resneck, W.G., Kaysser, T., Ursitti, J.A., Birkenmeier, C.S., Barker, J.E., Bloch, R.J. J. Cell. Sci. (2001)
- Cytoskeleton and vesicle mobility in astrocytes. Potokar, M., Kreft, M., Li, L., Daniel Andersson, J., Pangrsic, T., Chowdhury, H.H., Pekny, M., Zorec, R. Traffic (2007)
- Not just a plasma membrane protein: in cardiac muscle cells alpha-II spectrin also shows a close association with myofibrils. Bennett, P.M., Baines, A.J., Lecomte, M.C., Maggs, A.M., Pinder, J.C. J. Muscle Res. Cell. Motil. (2004)
- Cysteinyl leukotriene receptor 1 is involved in N-methyl-D-aspartate-mediated neuronal injury in mice. Ding, Q., Wei, E.Q., Zhang, Y.J., Zhang, W.P., Chen, Z. Acta Pharmacol. Sin. (2006)
- Repeated Methamphetamine Administration Alters Expression of the NMDA Receptor Channel {varepsilon}2 Subunit and Kinesins in the Mouse Brain. Yamamoto, H., Imai, K., Kamegaya, E., Takamatsu, Y., Irago, M., Hagino, Y., Kasai, S., Shimada, K., Yamamoto, T., Sora, I., Koga, H., Ikeda, K. Ann. N. Y. Acad. Sci. (2006)
- Ca2+/Calmodulin Kinase Kinase {alpha} Is Dispensable for Brain Development but Is Required for Distinct Memories in Male, though Not in Female, Mice. Mizuno, K., Ris, L., S??nchez-Capelo, A., Godaux, E., Giese, K.P. Mol. Cell. Biol. (2006)
- Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia. Zhu, C., Wang, X., Huang, Z., Qiu, L., Xu, F., Vahsen, N., Nilsson, M., Eriksson, P.S., Hagberg, H., Culmsee, C., Plesnila, N., Kroemer, G., Blomgren, K. Cell Death Differ. (2007)
- The role of the octarepeat region in neuroprotective function of the cellular prion protein. Mitteregger, G., Vosko, M., Krebs, B., Xiang, W., Kohlmannsperger, V., Nölting, S., Hamann, G.F., Kretzschmar, H.A. Brain Pathol. (2007)
- A Requirement for Microglial TLR4 in Leukocyte Recruitment into Brain in Response to Lipopolysaccharide. Zhou, H., Lapointe, B.M., Clark, S.R., Zbytnuik, L., Kubes, P. J. Immunol. (2006)
- Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. Jänicke, R.U., Ng, P., Sprengart, M.L., Porter, A.G. J. Biol. Chem. (1998)
- Activation of multiple pathways during photoreceptor apoptosis in the rd mouse. Doonan, F., Donovan, M., Cotter, T.G. Invest. Ophthalmol. Vis. Sci. (2005)
- Chromosomal location of three spectrin genes: relationship to the inherited hemolytic anemias of mouse and man. Birkenmeier, C.S., McFarland-Starr, E.C., Barker, J.E. Proc. Natl. Acad. Sci. U.S.A. (1988)
- BMI1 loss delays photoreceptor degeneration in Rd1 mice. Bmi1 loss and neuroprotection in Rd1 mice. Zencak, D., Crippa, S.V., Tekaya, M., Tanger, E., Schorderet, D.E., Munier, F.L., van Lohuizen, M., Arsenijevic, Y. Adv. Exp. Med. Biol. (2006)
- Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. Kuroda, N., Mitani, T., Takeda, N., Ishimaru, N., Arakaki, R., Hayashi, Y., Bando, Y., Izumi, K., Takahashi, T., Nomura, T., Sakaguchi, S., Ueno, T., Takahama, Y., Uchida, D., Sun, S., Kajiura, F., Mouri, Y., Han, H., Matsushima, A., Yamada, G., Matsumoto, M. J. Immunol. (2005)
- Autoantigen-specific CD4+CD28low T cell subset prevents autoimmune exocrinopathy in murine Sjögren's syndrome. Saegusa, K., Ishimaru, N., Yanagi, K., Haneji, N., Nishino, M., Azuma, M., Saito, I., Hayashi, Y. J. Immunol. (2000)
- Wavelet-based multi-resolution statistics for optical imaging signals: Application to automated detection of odour activated glomeruli in the mouse olfactory bulb. Bathellier, B., Van De Ville, D., Blu, T., Unser, M., Carleton, A. Neuroimage (2007)
- Severe destructive autoimmune lesions with aging in murine Sjögren's syndrome through Fas-mediated apoptosis. Ishimaru, N., Yoneda, T., Saegusa, K., Yanagi, K., Haneji, N., Moriyama, K., Saito, I., Hayashi, Y. Am. J. Pathol. (2000)
- Development of autoimmune exocrinopathy resembling Sjögren's syndrome in estrogen-deficient mice of healthy background. Ishimaru, N., Arakaki, R., Watanabe, M., Kobayashi, M., Miyazaki, K., Hayashi, Y. Am. J. Pathol. (2003)