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Chemical Compound Review

CHEMBL152798     2-amino-5,6,7,8-tetrahydro- 1H-pteridin-4-one

Synonyms: SureCN3454164, SureCN3454166, SureCN12807134, AC1L3U1P, 1008-35-1, ...
 
 
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Disease relevance of tetrahydropterin

 

High impact information on tetrahydropterin

 

Biological context of tetrahydropterin

 

Anatomical context of tetrahydropterin

 

Associations of tetrahydropterin with other chemical compounds

 

Gene context of tetrahydropterin

 

Analytical, diagnostic and therapeutic context of tetrahydropterin

References

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  3. (6R)-5,6,7,8-tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin. Ikemoto, K., Sugimoto, T., Murata, S., Tazawa, M., Nomura, T., Ichinose, H., Nagatsu, T. Biol. Chem. (2002) [Pubmed]
  4. Purification and characterization of the methylene tetrahydromethanopterin dehydrogenase MtdB and the methylene tetrahydrofolate dehydrogenase FolD from Hyphomicrobium zavarzinii ZV580. Goenrich, M., Bursy, J., Hübner, E., Linder, D., Schwartz, A.C., Vorholt, J.A. Arch. Microbiol. (2002) [Pubmed]
  5. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution. Colloc'h, N., el Hajji, M., Bachet, B., L'Hermite, G., Schiltz, M., Prangé, T., Castro, B., Mornon, J.P. Nat. Struct. Biol. (1997) [Pubmed]
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  7. Human tyrosine hydroxylase isoforms. Inhibition by excess tetrahydropterin and unusual behavior of isoform 3 after camp-dependent protein kinase phosphorylation. Alterio, J., Ravassard, P., Haavik, J., Le Caer, J.P., Biguet, N.F., Waksman, G., Mallet, J. J. Biol. Chem. (1998) [Pubmed]
  8. Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron. Andersson, K.K., Cox, D.D., Que, L., Flatmark, T., Haavik, J. J. Biol. Chem. (1988) [Pubmed]
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  11. A flexible loop in tyrosine hydroxylase controls coupling of amino acid hydroxylation to tetrahydropterin oxidation. Daubner, S.C., McGinnis, J.T., Gardner, M., Kroboth, S.L., Morris, A.R., Fitzpatrick, P.F. J. Mol. Biol. (2006) [Pubmed]
  12. Characterization of phenylalanine hydroxylase. Bloom, L.M., Benkovic, S.J., Gaffney, B.J. Biochemistry (1986) [Pubmed]
  13. Biosynthetic pathways of pteridines and their association with phenotypic expression in vitro in normal and neoplastic pigment cells from goldfish. Masada, M., Matsumoto, J., Akino, M. Pigment Cell Res. (1990) [Pubmed]
  14. Dihydropteridine reductase deficiency: diagnosis by leukocyte enzyme assay. Narisawa, K., Arai, N., Ishizawa, S., Ogasawara, Y., Onuma, A., Iinuma, K., Tada, K. Clin. Chim. Acta (1980) [Pubmed]
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  17. Effects of ligands on the mobility of an active-site loop in tyrosine hydroxylase as monitored by fluorescence anisotropy. Sura, G.R., Lasagna, M., Gawandi, V., Reinhart, G.D., Fitzpatrick, P.F. Biochemistry (2006) [Pubmed]
  18. Reactions catalyzed by the heme domain of inducible nitric oxide synthase: evidence for the involvement of tetrahydrobiopterin in electron transfer. Hurshman, A.R., Marletta, M.A. Biochemistry (2002) [Pubmed]
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  20. Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members. Iino, T., Tabata, M., Takikawa, S., Sawada, H., Shintaku, H., Ishikura, S., Hara, A. Arch. Biochem. Biophys. (2003) [Pubmed]
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  23. Studies on the interaction of a thiol-dependent hydrogen peroxide scavenging enzyme and phenylalanine hydroxylase. Milstien, S., Dorche, C., Kaufman, S. Arch. Biochem. Biophys. (1990) [Pubmed]
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  25. Purification of dihydropterin reductase using immobilized Cibacron Blue. Chauvin, M.M., Korri, K.K., Tirpak, A., Simpson, R.C., Scrimgeour, K.G. Can. J. Biochem. (1979) [Pubmed]
 
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