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Chemical Compound Review

CHEMBL1162486     (2S)-2-ethylhexanoic acid

Synonyms: KST-1A8072, CTK8E0262, AR-1A3262, AC1L366W, AC1Q5R00, ...
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Disease relevance of 2-ETHYLHEXANOIC ACID


High impact information on 2-ETHYLHEXANOIC ACID


Biological context of 2-ETHYLHEXANOIC ACID


Anatomical context of 2-ETHYLHEXANOIC ACID


Associations of 2-ETHYLHEXANOIC ACID with other chemical compounds


Gene context of 2-ETHYLHEXANOIC ACID


Analytical, diagnostic and therapeutic context of 2-ETHYLHEXANOIC ACID


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  2. 2-Ethylhexanoic acid: subchronic oral toxicity studies in the rat and mouse. Juberg, D.R., David, R.M., Katz, G.V., Bernard, L.G., Gordon, D.R., Vlaovic, M.S., Topping, D.C. Food Chem. Toxicol. (1998) [Pubmed]
  3. Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies. French, K.J., Strickler, M.D., Rock, D.A., Rock, D.A., Bennett, G.A., Wahlstrom, J.L., Goldstein, B.M., Jones, J.P. Biochemistry (2001) [Pubmed]
  4. Identification of the proximate peroxisome proliferator(s) derived from di (2-ethylhexyl) adipate and species differences in response. Cornu, M.C., Lhuguenot, J.C., Brady, A.M., Moore, R., Elcombe, C.R. Biochem. Pharmacol. (1992) [Pubmed]
  5. In vitro glucuronidation of peroxisomal proliferators: 2-ethylhexanoic acid enantiomers and their structural analogs. Hamdoune, M., Duclos, S., Mounie, J., Santona, L., Lhuguenot, J.C., Magdalou, J., Goudonnet, H. Toxicol. Appl. Pharmacol. (1995) [Pubmed]
  6. Sister-chromatid exchanges induced by vinyl esters and respective carboxylic acids in cultured human lymphocytes. Sipi, P., Järventaus, H., Norppa, H. Mutat. Res. (1992) [Pubmed]
  7. Characterization of the induction of cytosolic and microsomal epoxide hydrolases by 2-ethylhexanoic acid in mouse liver. Lundgren, B., Meijer, J., DePierre, J.W. Drug Metab. Dispos. (1987) [Pubmed]
  8. An assessment of the dietary uptake of di-2-(ethylhexyl) adipate (DEHA) in a limited population study. Loftus, N.J., Woollen, B.H., Steel, G.T., Wilks, M.F., Castle, L. Food Chem. Toxicol. (1994) [Pubmed]
  9. Assessment of the developmental toxicity of 2-ethylhexanoic acid in rats and rabbits. Hendrickx, A.G., Peterson, P.E., Tyl, R.W., Fisher, L.C., Fosnight, L.J., Kubena, M.F., Vrbanic, M.A., Katz, G.V. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1993) [Pubmed]
  10. Degradation of bis(2-ethylhexyl) phthalate constituents under methanogenic conditions. Ejlertsson, J., Svensson, B.H. Biodegradation (1996) [Pubmed]
  11. Effects of 2-ethylhexanoic acid on the production of reactive oxygen species in human polymorphonuclear leukocytes in vitro. Pennanen, S.M., Heiskanen, K.M., Savolainen, K.M., Komulainen, H. Toxicol. Lett. (2000) [Pubmed]
  12. Inhibition of animal acetyl-coenzyme A carboxylase by 2-(p-chlorophenoxy)-2-methylpropionic acid and 2-ethylhexanoic acid. Sumida, K., Kaneko, H., Yoshitake, A. Chemosphere (1996) [Pubmed]
  13. Simultaneous analysis of the di(2-ethylhexyl)phthalate metabolites 2-ethylhexanoic acid, 2-ethyl-3-hydroxyhexanoic acid and 2-ethyl-3-oxohexanoic acid in urine by gas chromatography-mass spectrometry. Wahl, H.G., Hong, Q., Stübe, D., Maier, M.E., Häring, H.U., Liebich, H.M. J. Chromatogr. B Biomed. Sci. Appl. (2001) [Pubmed]
  14. CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver. Pennanen, S., Kojo, A., Pasanen, M., Liesivuori, J., Juvonen, R.O., Komulainen, H. Human & experimental toxicology. (1996) [Pubmed]
  15. Exposure of newborn infants to di-(2-ethylhexyl)-phthalate and 2-ethylhexanoic acid following exchange transfusion with polyvinylchloride catheters. Plonait, S.L., Nau, H., Maier, R.F., Wittfoht, W., Obladen, M. Transfusion (1993) [Pubmed]
  16. Murine teratology and pharmacokinetics of the enantiomers of sodium 2-ethylhexanoate. Collins, M.D., Scott, W.J., Miller, S.J., Evans, D.A., Nau, H. Toxicol. Appl. Pharmacol. (1992) [Pubmed]
  17. Evaluation of workers' exposure to 2-ethylhexanoic acid (2-EHA) in Finnish sawmills. A field study. Kröger, S., Liesivuori, J., Manninen, A. International archives of occupational and environmental health. (1990) [Pubmed]
  18. Distribution of 2-ethylhexanoic acid in mice and rats after an intraperitoneal injection. Pennanen, S., Manninen, A. Pharmacol. Toxicol. (1991) [Pubmed]
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