Disease relevance of potassium iodate

• When 1.25 V was applied in 1.0 mM potassium iodate, approximately 4-log inactivation of Escherichia coli was observed in 30 min [1].
• CT scanning of the thyroid following oral administration of potassium iodate was performed on two sisters in whom raised calcitonin levels had been found at a pentagastrin stimulation test undertaken to screen for medullary carcinoma of the thyroid [2].
• A case of potassium iodate toxicity in a 22-year-old man was reported [3].

High impact information on potassium iodate

• The method used is a potentiometric titration of Sn (II) in 1 N HCI medium, using potassium iodate as the oxidizing agent in an atmosphere of nitrogen [4].
• The results showed that the comet assay failed to detect the presence of DNA damage after a treatment of cells by potassium iodate for concentrations up to 10 mM [5].
• Sulfur speciation in low molecular weight (LMW) subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values, aged subunits of glutenin as well as gluten, and gliadin have been investigated in situ by S K-edge X-ray absorption near-edge structure (XANES) spectroscopy [6].
• Simultaneous spectrophotometric and volumetric determinations of the antibiotic is based on the neutralization of the degraded product by dilute hydrochloric acid to get a pH approximately 2 to be conducive for redox titration using potassium iodate as titrant [7].
• Three months, six months and twelve months after admistration of potassium iodate, they were sacrificed and thyroids were excised [8].

Chemical compound and disease context of potassium iodate

• The influence of potassium iodate (KIO3) on the metabolism of Escherichia coli (E. coli) is investigated for the first time with the intrinsic fluorescence of tryptophan (Trp) and reduced nicotinamide adenine dinucleotide (NADH) [9].

Biological context of potassium iodate

• And the bacteria could not continue growing if the KIO3 was over 6.67 mmol/L.We could conclude that potassium iodate has great inhibiting effects on the growth of E. coli through the pathway of protein synthesis and respiratory chain [9].
• Iodine deficiency disorders constitute a major public health problem in India. The national IDD control programme (NIDDCP) relies solely on iodine supplementation through fortification of common salt with potassium iodate [10].

Associations of potassium iodate with other chemical compounds

• When the potassium iodate concentration was below 1.32 mmol/L, the intensity of tryptophan fluorescence decreased linearly whereas the NADH fluorescence did not change [9].
• A prospective study was carried out using a combination of propranolol and potassium iodate to assess whether there were beneficial effects in preparing hyperthyroid cats for surgical thyroidectomy [11].
• The charge transfer (CT) reactions between Fluclox and Diclox as electron donors and 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) pi-acceptor and potassium iodate via oxidation reduction reaction where the highly coloured complex species or the liberated iodine have been spectrophotometrically studied [12].

References