Chemical Compound Review:
Immepip 4-(3H-imidazol-4- ylmethyl)piperidine
Synonyms:
Tocris-0932, CHEMBL18661, AG-D-97885, SureCN3338054, SureCN6347746, ...
- Pre-synaptic histamine H(3) receptors regulate glutamate, but not GABA release in rat thalamus. Garduño-Torres, B., Treviño, M., Gutiérrez, R., Arias-Montaño, J.A. Neuropharmacology (2007)
- Histamine H3 receptor agonists reduce L-dopa-induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease. Gomez-Ramirez, J., Johnston, T.H., Visanji, N.P., Fox, S.H., Brotchie, J.M. Mov. Disord. (2006)
- H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Lamberty, Y., Margineanu, D.G., Dassesse, D., Klitgaard, H. Pharmacol. Res. (2003)
- A new potent and selective histamine H3 receptor agonist, 4-(1H-imidazol-4-ylmethyl)piperidine. Vollinga, R.C., de Koning, J.P., Jansen, F.P., Leurs, R., Menge, W.M., Timmerman, H. J. Med. Chem. (1994)
- Identification of zebrafish histamine H(1), H(2) and H(3) receptors and effects of histaminergic ligands on behavior. Peitsaro, N., Sundvik, M., Anichtchik, O.V., Kaslin, J., Panula, P. Biochem. Pharmacol. (2007)
- Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]GABA release from depolarization-stimulated slices of rat substantia nigra pars reticulata. Garcia, M., Floran, B., Arias-Montaño, J.A., Young, J.M., Aceves, J. Neuroscience (1997)
- Histamine H3 receptor activation inhibits dopamine D1 receptor-induced cAMP accumulation in rat striatal slices. Sánchez-Lemus, E., Arias-Montaño, J.A. Neurosci. Lett. (2004)
- Pharmacological analysis of immepip and imetit homologues. Further evidence for histamine H(3) receptor heterogeneity? Alves-Rodrigues, A., Lemstra, S., Vollinga, R.C., Menge, W.M., Timmerman, H., Leurs, R. Behav. Brain Res. (2001)
- Activation of spinal histamine H3 receptors inhibits mechanical nociception. Cannon, K.E., Nalwalk, J.W., Stadel, R., Ge, P., Lawson, D., Silos-Santiago, I., Hough, L.B. Eur. J. Pharmacol. (2003)
- In vivo modulation of rat hypothalamic histamine release by the histamine H3 receptor ligands, immepip and clobenpropit. Effects of intrahypothalamic and peripheral application. Jansen, F.P., Mochizuki, T., Yamamoto, Y., Timmerman, H., Yamatodani, A. Eur. J. Pharmacol. (1998)
- Histamine H3 receptors do not modulate reflex-evoked peristaltic motility in the isolated guinea-pig ileum. Poli, E., Pozzoli, C. Eur. J. Pharmacol. (1997)
- Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip. Lamberty, Y., Gower, A.J. Pharmacol. Biochem. Behav. (2004)
- Activation of histaminergic H3 receptors in the rat basolateral amygdala improves expression of fear memory and enhances acetylcholine release. Cangioli, I., Baldi, E., Mannaioni, P.F., Bucherelli, C., Blandina, P., Passani, M.B. Eur. J. Neurosci. (2002)