Chemical Compound Review:
Diacomit (E)-1-benzo[1,3]dioxol-5-yl- 4,4-dimethyl...
Synonyms:
STIRIPENTOL, Estiripentol, Stiripentolum, AC1NSKO6, SureCN216436, ...
- Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO study group. Chiron, C., Marchand, M.C., Tran, A., Rey, E., d'Athis, P., Vincent, J., Dulac, O., Pons, G. Lancet (2000)
- New anticonvulsant drugs. Focus on flunarizine, fosphenytoin, midazolam and stiripentol. Bebin, M., Bleck, T.P. Drugs (1994)
- Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-receptor channels. Quilichini, P.P., Chiron, C., Ben-Ari, Y., Gozlan, H. Epilepsia (2006)
- Differences in the patterns of phenytoin-induced malformations following stiripentol coadministration in three inbred mouse strains. Finnell, R.H., van Waes, M., Musselman, A., Kerr, B.M., Levy, R.H. Reprod. Toxicol. (1993)
- Michaelis-Menten kinetics of stiripentol in normal humans. Levy, R.H., Loiseau, P., Guyot, M., Blehaut, H.M., Tor, J., Moreland, T.A. Epilepsia (1984)
- Biphasic characteristic of interactions between stiripentol and carbamazepine in the mouse maximal electroshock-induced seizure model: a three-dimensional isobolographic analysis. Luszczki, J.J., Czuczwar, S.J. Naunyn Schmiedebergs Arch. Pharmacol. (2006)
- Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: in vitro and in vivo comparison and calculation of in vivo inhibition constants. Tran, A., Rey, E., Pons, G., Rousseau, M., d'Athis, P., Olive, G., Mather, G.G., Bishop, F.E., Wurden, C.J., Labroo, R., Trager, W.F., Kunze, K.L., Thummel, K.E., Vincent, J.C., Gillardin, J.M., Lepage, F., Levy, R.H. Clin. Pharmacol. Ther. (1997)
- Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis. Luszczki, J.J., Ratnaraj, N., Patsalos, P.N., Czuczwar, S.J. Epilepsia (2006)
- Stiripentol kinetics in epilepsy: nonlinearity and interactions. Levy, R.H., Loiseau, P., Guyot, M., Blehaut, H.M., Tor, J., Moreland, T.A. Clin. Pharmacol. Ther. (1984)
- Pharmacokinetic profile of a new anticonvulsant, stiripentol, in the rhesus monkey. Lin, H.S., Levy, R.H. Epilepsia (1983)
- Inhibitory effect of stiripentol on carbamazepine and saquinavir metabolism in human. Cazali, N., Tran, A., Treluyer, J.M., Rey, E., d'Athis, P., Vincent, J., Pons, G. British journal of clinical pharmacology. (2003)
- In vitro and in vivo investigations of dihydropyridine-based chemical delivery systems for anticonvulsants. Boddy, A.V., Zhang, K., Lepage, F., Tombret, F., Slatter, J.G., Baillie, T.A., Levy, R.H. Pharm. Res. (1991)
- Carbamazepine plus stiripentol: is polytherapy by design possible? Lockard, J.S., Levy, R.H. Epilepsia (1988)
- Comparative anticonvulsant potency and pharmacokinetics of (+)-and (-)-enantiomers of stiripentol. Shen, D.D., Levy, R.H., Savitch, J.L., Boddy, A.V., Tombret, F., Lepage, F. Epilepsy Res. (1992)
- In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism. Giraud, C., Treluyer, J.M., Rey, E., Chiron, C., Vincent, J., Pons, G., Tran, A. Drug Metab. Dispos. (2006)
- In vitro inhibition by stiripentol of rat brain cytochrome P-450-mediated naphthalene hydroxylation. Mesnil, M., Testa, B., Jenner, P. Xenobiotica (1988)
- Phenytoin and/or stiripentol in pregnancy: infant monkey hyperexcitability. Phillips, N.K., Lockard, J.S. Epilepsia (1993)
- Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation. Finnell, R.H., Bennett, G.D., Slattery, J.T., Amore, B.M., Bajpai, M., Levy, R.H. Teratology (1995)
- A new type of anticonvulsant, stiripentol. Pharmacological profile and neurochemical study. Poisson, M., Huguet, F., Savattier, A., Bakri-Logeais, F., Narcisse, G. Arzneimittel-Forschung. (1984)
- Stiripentol in acute/chronic efficacy tests in monkey model. Lockard, J.S., Levy, R.H., Rhodes, P.H., Moore, D.F. Epilepsia (1985)
- Stereoselective pharmacokinetics of stiripentol: an explanation for the development of tolerance to anticonvulsant effect. Arends, R.H., Zhang, K., Levy, R.H., Baillie, T.A., Shen, D.D. Epilepsy Res. (1994)