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Chemical Compound Review

AC1NSLDV     N-(ethylideneamino)-N-methyl- methanamide

Synonyms: ZINC00897463, N-[(Z)-ethylideneamino]-N-methylformamide
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Disease relevance of GYROMITRIN


High impact information on GYROMITRIN


Biological context of GYROMITRIN

  • Methylation of deoxyribonucleic acid in the rat by the mushroom poison gyromitrin [9].
  • The poison gyromitrin, found in the edible false morel Gyromitra esculenta Fr. ex Pers., caused in rats an increased diuresis in which urine was produced with a weak alkaline pH, a high excretion of sodium (530%), and potassium (210%) [10].

Anatomical context of GYROMITRIN


Associations of GYROMITRIN with other chemical compounds


Analytical, diagnostic and therapeutic context of GYROMITRIN

  • On the basis of [3H] inulin excretion an increased glomerular filtration was determined followed by a decrease 12 h after application of gyromitrin [10].


  1. Cancer induction in mice with acetaldehyde methylformylhydrazone of the false morel mushroom. Toth, B., Smith, J.W., Patil, K.D. J. Natl. Cancer Inst. (1981) [Pubmed]
  2. On the mutagenicity of metabolites derived from the mushroom poison gyromitrin. von der Hude, W., Braun, R. Toxicology (1983) [Pubmed]
  3. Acute oral toxicity of ethylidene gyromitrin in rabbits, rats and chickens. Mäkinen, S.M., Kreula, M., Kauppi, M. Food and cosmetics toxicology. (1977) [Pubmed]
  4. Formation of methylhydrazine from acetaldehyde N-methyl-N-formylhydrazone, a component of Gyromitra esculenta. Nagel, D., Wallcave, L., Toth, B., Kupper, R. Cancer Res. (1977) [Pubmed]
  5. Gas chromatography-mass spectrometry determination of the pentafluorobenzoyl derivative of methylhydrazine in false morel (Gyromitra esculenta) as a monitor for the content of the toxin gyromitrin. Arshadi, M., Nilsson, C., Magnusson, B. Journal of chromatography. A. (2006) [Pubmed]
  6. Methylation of rat and mouse DNA by the mushroom poison gyromitrin and its metabolite monomethylhydrazine. Bergman, K., Hellenäs, K.E. Cancer Lett. (1992) [Pubmed]
  7. The toxicology of 1-acetyl-2-methyl-2-formyl hydrazine (Ac-MFH). Braun, R., Weyl, G., Netter, K.J. Toxicol. Lett. (1981) [Pubmed]
  8. Indications for nitrosamide formation from the mushroom poison gyromitrin by rat liver microsomes. Braun, R., Greeff, U., Netter, K.J. Xenobiotica (1980) [Pubmed]
  9. Methylation of deoxyribonucleic acid in the rat by the mushroom poison gyromitrin. Hayman, E., Yokoyama, H., Gold, S. J. Agric. Food Chem. (1983) [Pubmed]
  10. Renal functional response to the mushroom poison gyromitrin. Braun, R., Kremer, J., Rau, H. Toxicology (1979) [Pubmed]
  11. Liver injury by the false morel poison gyromitrin. Braun, R., Greeff, U., Netter, K.J. Toxicology (1979) [Pubmed]
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