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Chemical Compound Review

Dicatron     1-phenylpropan-2-ylhydrazine

Synonyms: Phenizine, fenizin, Catron, Feniprazina, Feniprazyne, ...
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Disease relevance of Catron


Psychiatry related information on Catron


High impact information on Catron

  • Importantly, a perfect reverse complement of (C/G)TTAATTG, which was recently shown to be an optimal binding sequence for the homeodomain of Msx-1 protein (K.M. Catron, N. Iler, and C. Abate (1993) Mol. Cell. Biol. 13:2354-2365), was also located in the murine Msx-1 promoter [6].
  • They were not affected by pretreatment of frogs with the monoamine oxidase inhibitor pheniprazine (Catron) nor by the application of pheniprazine, angiotensin or serotonin in vitro [7].
  • Whereas the maximum effects on pheniprazine inhibition of rat liver MAO-B occurred at about 5 microM cyanide, concentrations of 5 mM were necessary for maximum stimulation of MAO-A inhibition [8].
  • The specificity of the retrograde axonal transport of 3H-serotonin (3H-5-HT) was radioautographically studied in the afferents to the olfactory bulb (O.B.). Injections of 3H-5-HT of different concentrations (10(-2), 10(-3), 10(-4) and 10(-5) M) were performed into the O.B. of catron pretreated rats [9].
  • The reversal of reserpine-like syndrome by administration of pargyline, pheniprazine or chronic administration of imipramine was accompanied by no changes in Ach-E and Ach-T activities [10].

Biological context of Catron


Associations of Catron with other chemical compounds


Gene context of Catron


Analytical, diagnostic and therapeutic context of Catron


  1. Microbial metabolism of phenelzine and pheniprazine. Foster, B.C., Coutts, R.T., Pasutto, F.M., Mozayani, A. Life Sci. (1988) [Pubmed]
  2. Evidence that a preferred substrate for type B monoamine oxidase mediates stimulus properties of MAO inhibitors: a possible role for beta-phenylethylamine in the cocaine cue. Colpaert, F.C., Niemegeers, C.J., Janssen, P.A. Pharmacol. Biochem. Behav. (1980) [Pubmed]
  3. Psychophysical evaluation of toxic effects on sensory systems. Hanson, H.M. Fed. Proc. (1975) [Pubmed]
  4. Effect of DL-erythro-dihydroxyphenylserine on the locomotor activity of the mouse. Mori, T., Nakajima, T., Hashimoto, H., Noto, T., Kato, N. Pharmacol. Biochem. Behav. (1985) [Pubmed]
  5. Effect of age of habit on susceptibility to cycloheximide-induced amnesia in mice. Quartermain, D., Botwinick, C.Y. Journal of comparative and physiological psychology. (1975) [Pubmed]
  6. Murine homeobox-containing gene, Msx-1: analysis of genomic organization, promoter structure, and potential autoregulatory cis-acting elements. Kuzuoka, M., Takahashi, T., Guron, C., Raghow, R. Genomics (1994) [Pubmed]
  7. Unusual alpha adrenergic receptor potency of methyldopa metabolites on melanocyte function. Pettinger, W.A. J. Pharmacol. Exp. Ther. (1977) [Pubmed]
  8. Some peculiar aspects of monoamine oxidase inhibition. Ramadan, Z.B., Dostert, P., Tipton, K.F. Neurobiology (Budapest, Hungary) (1999) [Pubmed]
  9. Is the retrograde axonal transport of 3H-5-HT a specific process of serotoninergic neurons? Araneda, S., Font, C., Pujol, J.F., Bobillier, P. J. Physiol. (Paris) (1981) [Pubmed]
  10. Choline acetyltransferase and acetylcholinesterase activities in mice brain during the antagonistic action of antidepressant drugs and Ro 4--1284. Zieliński, M., Korczak-Dziuba, K., Herman, Z.S. Polish journal of pharmacology and pharmacy. (1978) [Pubmed]
  11. Influence of MAO inhibitors on uptake and release of norepinephrine in rat brain in vitro. Ziance, R.J., Moxley, K., Mullis, M., Gray, W. Archives internationales de pharmacodynamie et de thérapie. (1977) [Pubmed]
  12. Effects of monoamine oxidase inhibitors on the borohydride stabilizable binding of serotonin and tryptamine in brain. Ungar, F., Callaghan, O.H. Res. Commun. Chem. Pathol. Pharmacol. (1977) [Pubmed]
  13. The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats. Herman, Z.S., Sokola, A., Lenartowicz, H., Zieliński, M., Depta, L. Polish journal of pharmacology and pharmacy. (1976) [Pubmed]
  14. Intensive care nursing: doctor problems. Case in point: Poor Sisters v. Catron (435 N.E. 2d 305 - IN). Regan, W.A. The Regan report on nursing law. (1982) [Pubmed]
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