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Chemical Compound Review

AG-G-72542     (2E,4E,6E,8E)-20- hydroxyicosa-2,4,6,8...

Synonyms: LMFA03060094, AC1O5TK0, 69845-60-9, Eicosatetraenoic acid, hydroxy-, 20-hydroxy-eicosatetraenoic acid, ...
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Disease relevance of Hydroxyeicosatetraenoic acid


High impact information on Hydroxyeicosatetraenoic acid


Biological context of Hydroxyeicosatetraenoic acid


Anatomical context of Hydroxyeicosatetraenoic acid


Associations of Hydroxyeicosatetraenoic acid with other chemical compounds


Gene context of Hydroxyeicosatetraenoic acid


Analytical, diagnostic and therapeutic context of Hydroxyeicosatetraenoic acid

  • The products were extracted, purified by high performance liquid chromatography, and identified by comparison of their retention times with those of authentic hydroxyeicosatetraenoic acid (HETE) standards and by gas chromatography-mass spectrometry [18].
  • We first developed a technique which combined detection by uv absorption due to conjugated diene and detection based on electrochemical (EC) reduction in reverse-phase HPLC for the selective determination of arachidonic acid hydroperoxides (hydroperoxyeicosatetraenoic acid, HPETE) and its reduced derivative, hydroxyeicosatetraenoic acid (HETE) [19].


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  18. Metabolism of arachidonic acid via the lipoxygenase pathway in human and murine glomeruli. Sraer, J., Rigaud, M., Bens, M., Rabinovitch, H., Ardaillou, R. J. Biol. Chem. (1983) [Pubmed]
  19. Selective quantification of arachidonic acid hydroperoxides and their hydroxy derivatives in reverse-phase high performance liquid chromatography. Terao, J., Shibata, S.S., Matsushita, S. Anal. Biochem. (1988) [Pubmed]
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