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Chemical Compound Review

Octanosol     octacosan-1-ol

Synonyms: octacosyl, Octacosanol, polycosanol, n-Octacosanol, OCTACOSANOL-1, ...
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Disease relevance of n-Octacosanol


High impact information on n-Octacosanol


Biological context of n-Octacosanol

  • The results indicate that octacosanol possesses an adipokinetic activity, which might affect the lipolysis process of muscle [7].

Anatomical context of n-Octacosanol


Associations of n-Octacosanol with other chemical compounds

  • Other substances touted as having ergogenic properties are carnitine, cobamamide, growth hormone releasers, octacosanol, and ginseng; again, there is no reliable scientific evidence to support claims that products containing these compounds have ergogenic potential, and heavy supplementation may lead to adverse effects [8].

Analytical, diagnostic and therapeutic context of n-Octacosanol


  1. Octacosanol in parkinsonism. Snider, S.R. Ann. Neurol. (1984) [Pubmed]
  2. Trial of octacosanol in amyotrophic lateral sclerosis. Norris, F.H., Denys, E.H., Fallat, R.J. Neurology (1986) [Pubmed]
  3. Inhibition of rat lipoprotein lipid peroxidation by the oral administration of D003, a mixture of very long-chain saturated fatty acids. Menéndez, R., Más, R., Amor, A.M., Ledón, N., Pérez, J., González, R.M., Rodeiro, I., Zayas, M., Jiménez, S. Can. J. Physiol. Pharmacol. (2002) [Pubmed]
  4. Octacosanol affects lipid metabolism in rats fed on a high-fat diet. Kato, S., Karino, K., Hasegawa, S., Nagasawa, J., Nagasaki, A., Eguchi, M., Ichinose, T., Tago, K., Okumori, H., Hamatani, K. Br. J. Nutr. (1995) [Pubmed]
  5. Biodistribution and metabolism of orally administered octacosanol in rats. Kabir, Y., Kimura, S. Ann. Nutr. Metab. (1993) [Pubmed]
  6. In vitro and in vivo study of octacosanol metabolism. Menéndez, R., Marrero, D., Más, R., Fernández, I., González, L., González, R.M. Arch. Med. Res. (2005) [Pubmed]
  7. Distribution of radioactive octacosanol in response to exercise in rats. Kabir, Y., Kimura, S. Die Nahrung. (1994) [Pubmed]
  8. Efficacy of nutritional supplements used by athletes. Beltz, S.D., Doering, P.L. Clinical pharmacy. (1993) [Pubmed]
  9. Structural analysis of wheat wax (Triticum aestivum, c.v. 'Naturastar' L.): from the molecular level to three dimensional crystals. Koch, K., Barthlott, W., Koch, S., Hommes, A., Wandelt, K., Mamdouh, W., De-Feyter, S., Broekmann, P. Planta (2006) [Pubmed]
  10. Analytical procedure for the determination of 1-octacosanol in plasma by solvent extraction and capillary gas chromatography. Gonzalez-Bravo, L., Magraner-Hernandez, J., Acosta-Gonzalez, P.C., Perez-Souto, N. J. Chromatogr. B, Biomed. Appl. (1996) [Pubmed]
  11. Policosanol, reaction time and event-related potentials. Fontani, G., Maffei, D., Lodi, L. Neuropsychobiology (2000) [Pubmed]
  12. Octacosanol supplementation increases running endurance time and improves biochemical parameters after exhaustion in trained rats. Kim, H., Park, S., Han, D.S., Park, T. Journal of medicinal food. (2003) [Pubmed]
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