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Chemical Compound Review

TALAMPICILLIN     (3-oxo-1H-isobenzofuran-1-yl) (2R,5R,6S)-6...

Synonyms: TAPC, Talampicilina, Talampicilline, SureCN34338, CHEBI:9391, ...
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Disease relevance of TALAMPICILLIN


High impact information on TALAMPICILLIN


Biological context of TALAMPICILLIN


Anatomical context of TALAMPICILLIN

  • The mean peak concentrations in serum (9.64 micrograms/ml), gingiva (4.72 micrograms/mg), mandibular bone (1.77 micrograms/ml), dental follicle (3.46 micrograms/ml), and dental pulp (5.53 micrograms/mg) all occurred at approximately 150 minutes after administration of talampicillin [11].
  • Eighty-one patients who underwent the extraction of impacted mandibular third molars in the nonfasting state were given a single oral dose of talampicillin (500 mg) preoperatively [11].

Analytical, diagnostic and therapeutic context of TALAMPICILLIN


  1. Letter: Infectious-mononucleosis rash after talampicillin. Morris, J. Lancet (1976) [Pubmed]
  2. Ampicillin concentrations in human dental granuloma after a single oral administration of talampicillin. Akimoto, Y., Nishimura, H., Komiya, M., Kaneko, K., Fujii, A., Tamura, T. Antimicrob. Agents Chemother. (1988) [Pubmed]
  3. Oral talampicillin in the treatment of gonorrhoea. Price, J.D., Fluker, J.L., Giles, J.H. The British journal of venereal diseases. (1977) [Pubmed]
  4. Treatment of uncomplicated gonorrhoea in women with talampicillin in a single oral 1.5 g dose. Mohanty, K.C., Roy, R.B. The British journal of venereal diseases. (1982) [Pubmed]
  5. Evaluation & comparison of single dose oral treatment of uncomplicated gonococcal urethritis in males with talampicillin & minocycline. Saeed, A., Roy, R.B. The British journal of clinical practice. (1979) [Pubmed]
  6. The bioavailability for four different commerically available brands of ampicillin compared with that of talampicillin. Hamilton-Miller, J.M., Brumfitt, W. J. Antimicrob. Chemother. (1979) [Pubmed]
  7. Oral bioavailability and in vitro stability of pivampicillin, bacampicillin, talampicillin, and ampicillin in horses. Ensink, J.M., Vulto, A.G., van Miert, A.S., Tukker, J.J., Winkel, M.B., Fluitman, M.A. Am. J. Vet. Res. (1996) [Pubmed]
  8. Talampicillin in the treatment and prophylaxis of urinary tract infection in children. Smellie, J.M., Grüneberg, R.N., Bantock, H.M., Katz, G. Chemotherapy. (1982) [Pubmed]
  9. The metabolism of talampicillin in rat, dog and man. Jeffery, D.J., Jones, K.H., Langley, P.F. Xenobiotica (1978) [Pubmed]
  10. Kinetics of talampicillin decomposition in solutions. Pawełczyk, E., Płotkowiak, Z., Helska, M. Acta poloniae pharmaceutica. (2002) [Pubmed]
  11. Ampicillin concentrations in human serum, gingiva, mandibular bone, dental follicle, and dental pulp following a single oral dose of talampicillin. Akimoto, Y., Kaneko, K., Fujii, A., Tamura, T. J. Oral Maxillofac. Surg. (1985) [Pubmed]
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