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Chemical Compound Review

Reuterin     3-hydroxypropanal

Synonyms: Hydracrolein, AG-K-49857, CHEBI:17871, HMDB03453, AC1L2NXE, ...
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Disease relevance of Reuterin


High impact information on Reuterin


Chemical compound and disease context of Reuterin


Biological context of Reuterin


Anatomical context of Reuterin

  • This strain showed a high survival after exposition to conditions simulating those existing in the gastrointestinal tract as well as a notable ability to adhere to intestinal cells, which suggests that its reuterin-producing ability may be used for the host benefit [13].

Gene context of Reuterin

  • The inhibitory effect of reuterin on Escherichia coli K12 was investigated at different conditions of temperature (10-30 degrees C), pH (4.5-6.5), and NaCl (0.5-3% (w/v)) [14].

Analytical, diagnostic and therapeutic context of Reuterin

  • In this report, we describe procedures for (i) producing reuterin in sufficient amounts to isolate from a fermentation mixture and (ii) isolating this substance by high-performance liquid chromatography [15].
  • The degree of tissue fixation by reuterin is significantly affected by its fixation conditions [6].


  1. Antagonistic activities of lactic acid bacteria in food and feed fermentations. Lindgren, S.E., Dobrogosz, W.J. FEMS Microbiol. Rev. (1990) [Pubmed]
  2. Chemical characterization of an antimicrobial substance produced by Lactobacillus reuteri. Talarico, T.L., Dobrogosz, W.J. Antimicrob. Agents Chemother. (1989) [Pubmed]
  3. Natural antimicrobial agent (reuterin) produced by lactobacillus reuteri for sanitization of biological tissues inoculated with pseudomonas aeruginosa. Liang, H.F., Chen, C.N., Chang, Y., Sung, H.W. Biotechnol. Bioeng. (2003) [Pubmed]
  4. The effect of Reuterin on Listeria monocytogenes and Escherichia coli O157:H7 in milk and cottage cheese. el-Ziney, M.G., Debevere, J.M. J. Food Prot. (1998) [Pubmed]
  5. Total synthesis of polycavernoside A, a lethal toxin of the red alga Polycavernosa tsudai. Blakemore, P.R., Browder, C.C., Hong, J., Lincoln, C.M., Nagornyy, P.A., Robarge, L.A., Wardrop, D.J., White, J.D. J. Org. Chem. (2005) [Pubmed]
  6. A natural compound (reuterin) produced by Lactobacillus reuteri for biological-tissue fixation. Sung, H.W., Chen, C.N., Liang, H.F., Hong, M.H. Biomaterials (2003) [Pubmed]
  7. The effect of reuterin on the lag time of single cells of Listeria innocua grown on a solid agar surface at different pH and NaCl concentrations. Rasch, M., M??tris, A., Baranyi, J., Bj??rn Budde, B. Int. J. Food Microbiol. (2007) [Pubmed]
  8. Biocompatibility study of biological tissues fixed by a natural compound (reuterin) produced by Lactobacillus reuteri. Sung, H.W., Chen, C.N., Chang, Y., Liang, H.F. Biomaterials (2002) [Pubmed]
  9. Glycerol metabolism in Lactobacillus collinoides: production of 3-hydroxypropionaldehyde, a precursor of acrolein. Sauvageot, N., Gouffi, K., Laplace, J.M., Auffray, Y. Int. J. Food Microbiol. (2000) [Pubmed]
  10. Effect of glucose on glycerol bioconversion by Lactobacillus reuteri. Lüthi-Peng, Q., Dileme, F.B., Puhan, Z. Appl. Microbiol. Biotechnol. (2002) [Pubmed]
  11. Application of reuterin produced by Lactobacillus reuteri 12002 for meat decontamination and preservation. El-Ziney, M.G., van den Tempel, T., Debevere, J., Jakobsen, M. J. Food Prot. (1999) [Pubmed]
  12. Characterisation and modelling of oscillatory behaviour related to reuterin production by Lactobacillus reuteri. Rasch, M., Barker, G.C., Sachau, K., Jakobsen, M., Arneborg, N. Int. J. Food Microbiol. (2002) [Pubmed]
  13. Characterization of a reuterin-producing Lactobacillus coryniformis strain isolated from a goat's milk cheese. Martín, R., Olivares, M., Marín, M.L., Xaus, J., Fernández, L., Rodríguez, J.M. Int. J. Food Microbiol. (2005) [Pubmed]
  14. The influence of temperature, salt and pH on the inhibitory effect of reuterin on Escherichia coli. Rasch, M. Int. J. Food Microbiol. (2002) [Pubmed]
  15. Production and isolation of reuterin, a growth inhibitor produced by Lactobacillus reuteri. Talarico, T.L., Casas, I.A., Chung, T.C., Dobrogosz, W.J. Antimicrob. Agents Chemother. (1988) [Pubmed]
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