The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Panaxytriol     heptadec-1-en-4,6-diyne- 3,9,10-triol

Synonyms: AG-H-50819, AC1L3QAA, CTK3E9251, LMFA05000027, AR-1C3355, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Panaxytriol


Biological context of Panaxytriol

  • Particularly, the proportion of cells in the G2/M phase of the cell cycle increased from 9 % to 26 and 48 %, respectively, after 24 and 36 h exposure to panaxytriol at 5 microg/ml [1].

Anatomical context of Panaxytriol

  • In this paper, the effect of panaxytriol on the cytotoxicity of mitomycin C (MMC) against a human gastric carcinoma cell line, MK-1, was investigated [4].
  • In addition, they suggest that the enhanced accumulation of MMC in MK-1 cells treated with panaxytriol can probably be attributed to the decreased fluidity of the cell membrane caused by panaxytriol [4].

Associations of Panaxytriol with other chemical compounds


Gene context of Panaxytriol

  • In contrast, when MK-1 cells were exposed to panaxytriol and then to MMC, only an additive effect was induced [4].

Analytical, diagnostic and therapeutic context of Panaxytriol


  1. Inhibitory effect of tumor cell proliferation and induction of G2/M cell cycle arrest by panaxytriol. Kim, J.Y., Lee, K.W., Kim, S.H., Wee, J.J., Kim, Y.S., Lee, H.J. Planta Med. (2002) [Pubmed]
  2. Inducible nitric oxide synthase inhibitors from Saposhnikovia divaricata and Panax quinquefolium. Wang, C.N., Shiao, Y.J., Kuo, Y.H., Chen, C.C., Lin, Y.L. Planta Med. (2000) [Pubmed]
  3. A possible mechanism for the cytotoxicity of a polyacetylenic alcohol, panaxytriol: inhibition of mitochondrial respiration. Matsunaga, H., Saita, T., Nagumo, F., Mori, M., Katano, M. Cancer Chemother. Pharmacol. (1995) [Pubmed]
  4. Potentiation of cytotoxicity of mitomycin C by a polyacetylenic alcohol, panaxytriol. Matsunaga, H., Katano, M., Saita, T., Yamamoto, H., Mori, M. Cancer Chemother. Pharmacol. (1994) [Pubmed]
  5. Studies on the panaxytriol of Panax ginseng C. A. Meyer. Isolation, determination and antitumor activity. Matsunaga, H., Katano, M., Yamamoto, H., Mori, M., Takata, K. Chem. Pharm. Bull. (1989) [Pubmed]
  6. Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. Nakano, Y., Matsunaga, H., Saita, T., Mori, M., Katano, M., Okabe, H. Biol. Pharm. Bull. (1998) [Pubmed]
  7. Determination of panaxytriol, a new type of tumour growth inhibitor from Panax ginseng, by capillary gas chromatography. Matsunaga, H., Katano, M., Yamamoto, H., Mori, M., Takata, K., Nishi, M. J. Chromatogr. (1989) [Pubmed]
  8. Screening of polyacetylenic alcohols in crude drugs using the ELISA for panaxytriol. Saita, T., Katano, M., Matsunaga, H., Kouno, I., Fujito, H., Mori, M. Biol. Pharm. Bull. (1995) [Pubmed]
WikiGenes - Universities