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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Psychiatry related information on Apiaceae


High impact information on Apiaceae


Biological context of Apiaceae


Anatomical context of Apiaceae


Associations of Apiaceae with chemical compounds


Gene context of Apiaceae

  • Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and ERbeta: differential transcription activity between ferutinine-liganded ER(alpha) and ERbeta [16].
  • Depressaria pastinacella, the parsnip webworm, a specialist on two genera in the Apiaceae, routinely consumes plant tissues high in furanocoumarin content and is capable of rapid cytochrome P450-mediated detoxification of these compounds [17].
  • We previously reported that a total methanolic extract of the underground part of Angelica gigas Nakai (Umbelliferae) (here-in-after abbreviated AG) significantly inhibited acetylcholinesterase (AChE) activity [18].
  • (Umbelliferae) showed potential tyrosinase inhibition against mushroom tyrosinase [19].
  • In order to evaluate the pharmacological activities of Chinese medicine, nine Umbelliferae plants were selected and their restoring activity against dexamethasone-induced disorders, liver protective activity, antimicrobial activity, anti-inflammatory activity and antimutagenic activity were tested and compared [20].

Analytical, diagnostic and therapeutic context of Apiaceae


  1. Anticonvulsant activity of Heracleum persicum seed. Sayyah, M., Moaied, S., Kamalinejad, M. Journal of ethnopharmacology. (2005) [Pubmed]
  2. Expression of a coriander desaturase results in petroselinic acid production in transgenic tobacco. Cahoon, E.B., Shanklin, J., Ohlrogge, J.B. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  3. Skin testing with recombinant allergens rBet v 1 and birch profilin, rBet v 2: diagnostic value for birch pollen and associated allergies. Pauli, G., Oster, J.P., Deviller, P., Heiss, S., Bessot, J.C., Susani, M., Ferreira, F., Kraft, D., Valenta, R. J. Allergy Clin. Immunol. (1996) [Pubmed]
  4. Anti-angiogenic activity of torilin, a sesquiterpene compound isolated from Torilis japonica. Kim, M.S., Lee, Y.M., Moon, E.J., Kim, S.E., Lee, J.J., Kim, K.W. Int. J. Cancer (2000) [Pubmed]
  5. Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Zheng, G.Q., Kenney, P.M., Zhang, J., Lam, L.K. Carcinogenesis (1992) [Pubmed]
  6. Geranium sanguineum (Geraniaceae) seed oil: a new source of petroselinic and vernolic acid. Tsevegsuren, N., Aitzetmuller, K., Vosmann, K. Lipids (2004) [Pubmed]
  7. Molecular evolution of flavonoid dioxygenases in the family Apiaceae. Gebhardt, Y., Witte, S., Forkmann, G., Lukacin, R., Matern, U., Martens, S. Phytochemistry (2005) [Pubmed]
  8. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Ryu, S.Y., Kou, N.Y., Choi, H.S., Ryu, H., Kim, T.S., Kim, K.M. Planta Med. (2001) [Pubmed]
  9. An acidic polysaccharide having activity on the reticuloendothelial system from the roots and rhizomes of Saposhnikovia divaricata. Shimizu, N., Tomoda, M., Gonda, R., Kanari, M., Kubota, A., Kubota, A. Chem. Pharm. Bull. (1989) [Pubmed]
  10. Inducible nitric oxide synthase inhibitor of the Chinese herb I. Saposhnikovia divaricata (Turcz.) Schischk. Wang, C.C., Chen, L.G., Yang, L.L. Cancer Lett. (1999) [Pubmed]
  11. Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. Akihisa, T., Tokuda, H., Ukiya, M., Iizuka, M., Schneider, S., Ogasawara, K., Mukainaka, T., Iwatsuki, K., Suzuki, T., Nishino, H. Cancer Lett. (2003) [Pubmed]
  12. The genus Thapsia as a source of petroselinic acid. Avato, P., Fanizzi, F.P., Rosito, I. Lipids (2001) [Pubmed]
  13. Anethofuran, carvone, and limonene: potential cancer chemopreventive agents from dill weed oil and caraway oil. Zheng, G.Q., Kenney, P.M., Lam, L.K. Planta Med. (1992) [Pubmed]
  14. Lignan profiles of indoor-cultivated Anthriscus sylvestris. Koulman, A., Batterman, S., van Putten, F.M., Bos, R., Quax, W.J. Planta Med. (2003) [Pubmed]
  15. Chemical analysis and antimicrobial studies on three species of Ferulago from Greece. Demetzos, C., Perdetzoglou, D., Gazouli, M., Tan, K., Economakis, C. Planta Med. (2000) [Pubmed]
  16. Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and ERbeta: differential transcription activity between ferutinine-liganded ER(alpha) and ERbeta. Ikeda, K., Arao, Y., Otsuka, H., Nomoto, S., Horiguchi, H., Kato, S., Kayama, F. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  17. Characterization and evolution of furanocoumarin-inducible cytochrome P450s in the parsnip webworm, Depressaria pastinacella. Li, W., Zangerl, A.R., Schuler, M.A., Berenbaum, M.R. Insect Mol. Biol. (2004) [Pubmed]
  18. Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice. Kang, S.Y., Lee, K.Y., Park, M.J., Kim, Y.C., Markelonis, G.J., Oh, T.H., Kim, Y.C. Neurobiology of learning and memory. (2003) [Pubmed]
  19. Tyrosinase-inhibitory furanocoumarin from Angelica dahurica. Piao, X.L., Baek, S.H., Park, M.K., Park, J.H. Biol. Pharm. Bull. (2004) [Pubmed]
  20. Pharmacological activities of water extracts of Umbelliferae plants. Kim, C.M., Heo, M.Y., Kim, H.P., Sin, K.S., Pachaly, P. Arch. Pharm. Res. (1991) [Pubmed]
  21. Purification and antigenicity of flavone synthase I from irradiated parsley cells. Lukacin, R., Matern, U., Junghanns, K.T., Heskamp, M.L., Britsch, L., Forkmann, G., Martens, S. Arch. Biochem. Biophys. (2001) [Pubmed]
  22. Hypoglycemic effect of aqueous extract of Ammi visnaga in normal and streptozotocin-induced diabetic rats. Jouad, H., Maghrani, M., Eddouks, M. Journal of herbal pharmacotherapy. (2002) [Pubmed]
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