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Gene Review

RBBP9  -  retinoblastoma binding protein 9

Homo sapiens

Synonyms: B5T-overexpressed gene protein, BOG, Bog, Protein BOG, RBBP-10, ...
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High impact information on RBBP9

  • Humic acids extracted from peat (Vasuygan Bog, Tomsk Region, Russian Federation) induce the phototransformation of 4-chlorophenol at 365 and 222 nm [1].
  • Platinum, palladium, rhodium, iridium and osmium were found to be enriched relative to their expected natural concentrations in peat samples from Thoreau's Bog, an ombrotrophic peat bog in Concord, Massachusetts. The source of osmium into the bog was determined from its isotopic composition (187Os/188Os) [2].
  • The beginning of Hg contamination from anthropogenic sources dates from AD 1475 at the Luther Bog, corresponding to biomass burning for agricultural activities by Native North Americans [3].
  • The other was a natural fen (Cedar Bog) in proximity to atrazine-treated cornfields [4].
  • Assignment of the Bog gene (RBBP9) to syntenic regions of mouse chromosome 2G1-H1 and human chromosome 20p11.2 by fluorescence in situ hybridization [5].

Biological context of RBBP9

  • RBBP10 spans about 9.6 kb of the genome and consists of six exons and five introns [6].
  • Spatial and temporal performance of the miniface (free air CO2 enrichment) system on Bog Ecosystems in northern and Central Europe [7].
  • The basis of the assessment is Broad Habitats, a classification developed as part of the United Kingdom (UK) Biodiversity Action Plan. Improved Grassland, Neutral Grassland and Bog Broad Habitats occupy the largest area of NI, which holds a large proportion of the UK Neutral Grassland and Fen Marsh and Swamp Broad Habitat resource [8].

Anatomical context of RBBP9

  • The COS 7 cell transfected with the ORF of RBBP10 showed that the protein was distributed both in the cytoplasm and in the nucleus [6].

Other interactions of RBBP9


Analytical, diagnostic and therapeutic context of RBBP9

  • Using the yeast two-hybrid system and co-immunoprecipitation, we demonstrated that Bog binds to Rb [9].
  • DNA extracted from Cedar Bog samples did not yield PCR products, and the corresponding Southern hybridization signals were absent [4].
  • From May through November 1993 and 1994, Lymnaea stagnalis appressa were collected from a stream adjacent to Cedarburg Bog, Ozaukee County, Wisconsin. Observations of cercarial shedding and subsequent dissection of snails revealed a relatively depauperate digenean component community consisting primarily of 3 common species [10].
  • Results for copper, lead and zinc chemical fractionation of peat profiles from Ringinglow Bog, near Sheffield, Great Britain, are reported and discussed [11].


  1. Fluorescence analysis of photoinduced degradation of ecotoxicants in the presence of humic acids. Tchaikovskaya, O.N., Sokolova, I.V., Yudina, N.V. Luminescence : the journal of biological and chemical luminescence. (2005) [Pubmed]
  2. Source characterisation of atmospheric platinum group element deposition into an ombrotrophic peat bog. Rauch, S., Hemond, H.F., Peucker-Ehrenbrink, B. Journal of environmental monitoring : JEM. (2004) [Pubmed]
  3. Predominant anthropogenic sources and rates of atmospheric mercury accumulation in southern Ontario recorded by peat cores from three bogs: comparison with natural "background" values (past 8000 years). Givelet, N., Roos-Barraclough, F., Shotyk, W. Journal of environmental monitoring : JEM. (2003) [Pubmed]
  4. Atrazine mineralization potential in two wetlands. Anderson, K.L., Wheeler, K.A., Robinson, J.B., Tuovinen, O.H. Water Res. (2002) [Pubmed]
  5. Assignment of the Bog gene (RBBP9) to syntenic regions of mouse chromosome 2G1-H1 and human chromosome 20p11.2 by fluorescence in situ hybridization. Woitach, J.T., Hong, R., Keck, C.L., Zimonjic, D.B., Popescu, N.C., Thorgeirsson, S.S. Cytogenet. Cell Genet. (1999) [Pubmed]
  6. Cloning and expression of a novel retinoblastoma binding protein cDNA, RBBP10. Chen, J.Z., Yang, Q.S., Wang, S., Meng, X.F., Ying, K., Xie, Y., Ma, Y.M. Biochem. Genet. (2002) [Pubmed]
  7. Spatial and temporal performance of the miniface (free air CO2 enrichment) system on Bog Ecosystems in northern and Central Europe. Miglietta, F., Hoosbeek, M.R., Foot, J., Gigon, F., Hassinen, A., Heijmans, M., Peressotti, A., Saarinen, T., Van Breemen, N., Wallén, B. Environmental monitoring and assessment. (2001) [Pubmed]
  8. Sampling Broad Habitat change to assess biodiversity conservation action in Northern Ireland. Cooper, A., McCann, T., Meharg, M.J. J. Environ. Manage. (2003) [Pubmed]
  9. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Woitach, J.T., Zhang, M., Niu, C.H., Thorgeirsson, S.S. Nat. Genet. (1998) [Pubmed]
  10. Larval trematode assemblages in the snail Lymnaea stagnalis from southeastern Wisconsin. Yoder, H.R., Coggins, J.R. J. Parasitol. (1998) [Pubmed]
  11. Chemical fractionation of copper, lead and zinc in ombrotrophic peat. Jones, J.M. Environ. Pollut. (1987) [Pubmed]
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