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Gene Review

ARID4A  -  AT rich interactive domain 4A (RBP1-like)

Homo sapiens

Synonyms: ARID domain-containing protein 4A, AT-rich interactive domain-containing protein 4A, RBBP-1, RBBP1, RBP-1, ...
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Disease relevance of ARID4A


High impact information on ARID4A


Biological context of ARID4A


Anatomical context of ARID4A


Associations of ARID4A with chemical compounds


Other interactions of ARID4A


Analytical, diagnostic and therapeutic context of ARID4A


  1. RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence. Binda, O., Roy, J.S., Branton, P.E. Mol. Cell. Biol. (2006) [Pubmed]
  2. Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells. Roesch, A., Becker, B., Schneider-Brachert, W., Hagen, I., Landthaler, M., Vogt, T. J. Invest. Dermatol. (2006) [Pubmed]
  3. Deficiency of a novel retinoblastoma binding protein 2-homolog is a consistent feature of sporadic human melanoma skin cancer. Vogt, T., Kroiss, M., McClelland, M., Gruss, C., Becker, B., Bosserhoff, A.K., Rumpler, G., Bogenrieder, T., Landthaler, M., Stolz, W. Lab. Invest. (1999) [Pubmed]
  4. RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis. Cao, J., Gao, T., Stanbridge, E.J., Irie, R. J. Natl. Cancer Inst. (2001) [Pubmed]
  5. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Woitach, J.T., Zhang, M., Niu, C.H., Thorgeirsson, S.S. Nat. Genet. (1998) [Pubmed]
  6. Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Kaelin, W.G., Krek, W., Sellers, W.R., DeCaprio, J.A., Ajchenbaum, F., Fuchs, C.S., Chittenden, T., Li, Y., Farnham, P.J., Blanar, M.A. Cell (1992) [Pubmed]
  7. Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product. Defeo-Jones, D., Huang, P.S., Jones, R.E., Haskell, K.M., Vuocolo, G.A., Hanobik, M.G., Huber, H.E., Oliff, A. Nature (1991) [Pubmed]
  8. Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Takeuchi, T., Yamazaki, Y., Katoh-Fukui, Y., Tsuchiya, R., Kondo, S., Motoyama, J., Higashinakagawa, T. Genes Dev. (1995) [Pubmed]
  9. The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action. Abbondanza, C., Medici, N., Nigro, V., Rossi, V., Gallo, L., Piluso, G., Belsito, A., Roscigno, A., Bontempo, P., Puca, A.A., Molinari, A.M., Moncharmont, B., Puca, G.A. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  10. Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites. Otterson, G.A., Kratzke, R.A., Lin, A.Y., Johnston, P.G., Kaye, F.J. Oncogene (1993) [Pubmed]
  11. RBP1 induces growth arrest by repression of E2F-dependent transcription. Lai, A., Marcellus, R.C., Corbeil, H.B., Branton, P.E. Oncogene (1999) [Pubmed]
  12. Retinoblastoma protein (pRB) was significantly phosphorylated through a Ras-to-MAPK pathway in mutant K-ras stably transfected human adrenocortical cells. Chen, Y.F., Chiu, H.H., Wu, C.H., Wang, J.Y., Chen, F.M., Tzou, W.H., Shin, S.J., Lin, S.R. DNA Cell Biol. (2003) [Pubmed]
  13. Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta. Kelm, R.J., Elder, P.K., Strauch, A.R., Getz, M.J. J. Biol. Chem. (1997) [Pubmed]
  14. Cytotoxic T lymphocytes that recognize decameric peptide sequences of retinoblastoma binding protein 1 (RBP-1) associated with human breast cancer. Takahashi, T., Cao, J., Hoon, D.S., Irie, R.F. Br. J. Cancer (1999) [Pubmed]
  15. Estrogen Receptor Isoform-specific Regulation of the Retinoblastoma-binding Protein 1 (RBBP1) Gene: ROLES OF AF1 AND ENHANCER ELEMENTS. Monroe, D.G., Secreto, F.J., Hawse, J.R., Subramaniam, M., Khosla, S., Spelsberg, T.C. J. Biol. Chem. (2006) [Pubmed]
  16. Determinants of Rbp1p Localization in Specific Cytoplasmic mRNA-processing Foci, P-bodies. Jang, L.T., Buu, L.M., Lee, F.J. J. Biol. Chem. (2006) [Pubmed]
  17. Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product. Numata, S., Claudio, P.P., Dean, C., Giordano, A., Croce, C.M. Cancer Res. (1999) [Pubmed]
  18. Cloning and expression of a novel retinoblastoma binding protein cDNA, RBBP10. Chen, J.Z., Yang, Q.S., Wang, S., Meng, X.F., Ying, K., Xie, Y., Ma, Y.M. Biochem. Genet. (2002) [Pubmed]
  19. Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. Monroe, D.G., Secreto, F.J., Subramaniam, M., Getz, B.J., Khosla, S., Spelsberg, T.C. Mol. Endocrinol. (2005) [Pubmed]
  20. Molecular cloning and characterization of a novel retinoblastoma-binding protein. Fusco, C., Reymond, A., Zervos, A.S. Genomics (1998) [Pubmed]
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