Gene Review:
Asic2 - acid-sensing (proton-gated) ion channel 2
Mus musculus
Synonyms:
ACIC2, ASIC2, Accn1, Acid-sensing ion channel 2, Amiloride-sensitive brain sodium channel, ...
- Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones. Drew, L.J., Rohrer, D.K., Price, M.P., Blaver, K.E., Cockayne, D.A., Cesare, P., Wood, J.N. J. Physiol. (Lond.) (2004)
- Acid-sensing ion channel 2 contributes a major component to acid-evoked excitatory responses in spiral ganglion neurons and plays a role in noise susceptibility of mice. Peng, B.G., Ahmad, S., Chen, S., Chen, P., Price, M.P., Lin, X. J. Neurosci. (2004)
- The mammalian sodium channel BNC1 is required for normal touch sensation. Price, M.P., Lewin, G.R., McIlwrath, S.L., Cheng, C., Xie, J., Heppenstall, P.A., Stucky, C.L., Mannsfeldt, A.G., Brennan, T.J., Drummond, H.A., Qiao, J., Benson, C.J., Tarr, D.E., Hrstka, R.F., Yang, B., Williamson, R.A., Welsh, M.J. Nature (2000)
- Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Benson, C.J., Xie, J., Wemmie, J.A., Price, M.P., Henss, J.M., Welsh, M.J., Snyder, P.M. Proc. Natl. Acad. Sci. U.S.A. (2002)
- The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons. Duggan, A., Garcia-Anoveros, J., Corey, D.P. J. Biol. Chem. (2002)
- The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability. McIlwrath, S.L., Hu, J., Anirudhan, G., Shin, J.B., Lewin, G.R. Neuroscience (2005)
- Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration. Ettaiche, M., Guy, N., Hofman, P., Lazdunski, M., Waldmann, R. J. Neurosci. (2004)
- Acid-sensing ion channel-2 is not necessary for sour taste in mice. Richter, T.A., Dvoryanchikov, G.A., Roper, S.D., Chaudhari, N. J. Neurosci. (2004)
- Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons. Askwith, C.C., Wemmie, J.A., Price, M.P., Rokhlina, T., Welsh, M.J. J. Biol. Chem. (2004)
- Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia. Hughes, P.A., Brierley, S.M., Young, R.L., Blackshaw, L.A. J. Comp. Neurol. (2007)