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MeSH Review

Nerve Endings

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Disease relevance of Nerve Endings


Psychiatry related information on Nerve Endings

  • These results support the hypothesis that persistent elevations of Abeta, which normally operates as a modulator of N-type voltage gated calcium channels, could increase internal nerve ending Ca2+ and excitatory neurotransmitter release to produce the early neurotoxic effects that eventually lead to Alzheimer's disease [6].

High impact information on Nerve Endings


Chemical compound and disease context of Nerve Endings


Biological context of Nerve Endings


Anatomical context of Nerve Endings


Associations of Nerve Endings with chemical compounds


Gene context of Nerve Endings

  • VAMP-1 was not present in the acinar cell but was found in the nerve endings innervating the acini [31].
  • We report that isolated nerve endings contain immunoreactive endothelin, the level of which is regulated by homeostatic mechanisms involved in control of water balance [32].
  • In addition, aFGF, released from the traumatized nerve endings, may be one of the first signals initiating protective recovery and repair processes following damaging auditory stimuli [33].
  • In the vestibular organs, KCNQ4 is restricted to the type I hair cells and the afferent calyx-like nerve endings ensheathing these sensory cells [34].
  • NPY nerve endings makes synaptic contact with the POMC/Y1-R-positive neurons [35].

Analytical, diagnostic and therapeutic context of Nerve Endings


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  3. Norepinephrine release from the ischemic heart is greatly enhanced in mice lacking histamine H3 receptors. Koyama, M., Seyedi, N., Fung-Leung, W.P., Lovenberg, T.W., Levi, R. Mol. Pharmacol. (2003) [Pubmed]
  4. Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. Gundersen, V., Fonnum, F., Ottersen, O.P., Storm-Mathisen, J. J. Cereb. Blood Flow Metab. (2001) [Pubmed]
  5. Motor nerve ending disorder in myasthenia gravis. Roe, R.D., Riker, W.F., Standaert, F.G. Neurology (1988) [Pubmed]
  6. Incubation of nerve endings with a physiological concentration of Abeta1-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release. Bobich, J.A., Zheng, Q., Campbell, A. J. Alzheimers Dis. (2004) [Pubmed]
  7. Angiotensin, thirst, and sodium appetite. Fitzsimons, J.T. Physiol. Rev. (1998) [Pubmed]
  8. Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Trottier, Y., Devys, D., Imbert, G., Saudou, F., An, I., Lutz, Y., Weber, C., Agid, Y., Hirsch, E.C., Mandel, J.L. Nat. Genet. (1995) [Pubmed]
  9. The mammalian sodium channel BNC1 is required for normal touch sensation. Price, M.P., Lewin, G.R., McIlwrath, S.L., Cheng, C., Xie, J., Heppenstall, P.A., Stucky, C.L., Mannsfeldt, A.G., Brennan, T.J., Drummond, H.A., Qiao, J., Benson, C.J., Tarr, D.E., Hrstka, R.F., Yang, B., Williamson, R.A., Welsh, M.J. Nature (2000) [Pubmed]
  10. Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells. Rorsman, P., Bokvist, K., Ammälä, C., Arkhammar, P., Berggren, P.O., Larsson, O., Wåhlander, K. Nature (1991) [Pubmed]
  11. Relaxin affects the release of oxytocin and vasopressin from the neurohypophysis. Dayanithi, G., Cazalis, M., Nordmann, J.J. Nature (1987) [Pubmed]
  12. Differential expression of sumatriptan-sensitive 5-hydroxytryptamine receptors in human trigeminal ganglia and cerebral blood vessels. Bouchelet, I., Cohen, Z., Case, B., Séguéla, P., Hamel, E. Mol. Pharmacol. (1996) [Pubmed]
  13. Angiotensin II, adhesion, and cardiac fibrosis. Schnee, J.M., Hsueh, W.A. Cardiovasc. Res. (2000) [Pubmed]
  14. [3H]GBR 12935 binding to dopamine uptake sites in the human brain. De Keyser, J., De Backer, J.P., Ebinger, G., Vauquelin, G. J. Neurochem. (1989) [Pubmed]
  15. Effect of tetanus toxin on oxytocin and vasopressin release from nerve endings of the neurohypophysis. Halpern, J.L., Habig, W.H., Trenchard, H., Russell, J.T. J. Neurochem. (1990) [Pubmed]
  16. Effect of bicuculline-induced status epilepticus on prostaglandins and hydroxyeicosatetraenoic acids in rat brain subcellular fractions. Birkle, D.L., Bazan, N.G. J. Neurochem. (1987) [Pubmed]
  17. Proadrenomedullin NH(2)-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings. Shimosawa, T., Ito, Y., Ando, K., Kitamura, K., Kangawa, K., Fujita, T. J. Clin. Invest. (1995) [Pubmed]
  18. CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain. Aronin, N., Chase, K., Young, C., Sapp, E., Schwarz, C., Matta, N., Kornreich, R., Landwehrmeyer, B., Bird, E., Beal, M.F. Neuron (1995) [Pubmed]
  19. Bradykinin B2-receptor activation augments norepinephrine exocytosis from cardiac sympathetic nerve endings. Mediation by autocrine/paracrine mechanisms. Seyedi, N., Win, T., Lander, H.M., Levi, R. Circ. Res. (1997) [Pubmed]
  20. Selective inhibition of synaptosomal proline uptake by leucine and methionine enkephalins. Rhoads, D.E., Peterson, N.A., Raghupathy, E. J. Biol. Chem. (1983) [Pubmed]
  21. Cyclic AMP-dependent phosphorylation of the alpha subunit of the sodium channel in synaptic nerve ending particles. Costa, M.R., Catterall, W.A. J. Biol. Chem. (1984) [Pubmed]
  22. Presynaptic neurones may contribute a unique glycoprotein to the extracellular matrix at the synapse. Caroni, P., Carlson, S.S., Schweitzer, E., Kelly, R.B. Nature (1985) [Pubmed]
  23. Dopamine stimulates the degradation of gonadotropin releasing hormone by rat synaptosomes. Marcano de Cotte, D., De Menezes, C.E., Bennett, G.W., Edwardson, J.A. Nature (1980) [Pubmed]
  24. Dopamine modulates cholecystokinin release in neostriatum. Meyer, D.K., Krauss, J. Nature (1983) [Pubmed]
  25. Haloperidol-induced plasticity of axon terminals in rat substantia nigra. Benes, F.M., Paskevich, P.A., Domesick, V.B. Science (1983) [Pubmed]
  26. Evidence for extramitochondrial pyruvate dehydrogenase involved in acetylcholine synthesis in nerve endings. Lefresne, P., Beaujouan, J.C., Glowinski, J. Nature (1978) [Pubmed]
  27. Positron emission tomography after MPTP: observations relating to the cause of Parkinson's disease. Calne, D.B., Langston, J.W., Martin, W.R., Stoessl, A.J., Ruth, T.J., Adam, M.J., Pate, B.D., Schulzer, M. Nature (1985) [Pubmed]
  28. The mechanism of kainic acid neurotoxicity. Garthwaite, J., Garthwaite, G. Nature (1983) [Pubmed]
  29. Release of substance P from isolated nerve endings. Schenker, C., Mroz, E.A., Leeman, S.E. Nature (1976) [Pubmed]
  30. Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Gilon, P., Henquin, J.C. Endocr. Rev. (2001) [Pubmed]
  31. The vesicle-associated membrane protein family of proteins in rat pancreatic and parotid acinar cells. Gaisano, H.Y., Sheu, L., Grondin, G., Ghai, M., Bouquillon, A., Lowe, A., Beaudoin, A., Trimble, W.S. Gastroenterology (1996) [Pubmed]
  32. Endothelin regulation of neuropeptide release from nerve endings of the posterior pituitary. Ritz, M.F., Stuenkel, E.L., Dayanithi, G., Jones, R., Nordmann, J.J. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  33. The site of action of neuronal acidic fibroblast growth factor is the organ of Corti of the rat cochlea. Pirvola, U., Cao, Y., Oellig, C., Suoqiang, Z., Pettersson, R.F., Ylikoski, J. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  34. KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway. Kharkovets, T., Hardelin, J.P., Safieddine, S., Schweizer, M., El-Amraoui, A., Petit, C., Jentsch, T.J. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  35. Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Hökfelt, T., Broberger, C., Zhang, X., Diez, M., Kopp, J., Xu, Z., Landry, M., Bao, L., Schalling, M., Koistinaho, J., DeArmond, S.J., Prusiner, S., Gong, J., Walsh, J.H. Brain Res. Brain Res. Rev. (1998) [Pubmed]
  36. Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain. Baumert, M., Maycox, P.R., Navone, F., De Camilli, P., Jahn, R. EMBO J. (1989) [Pubmed]
  37. Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction. Dae, M.W., Herre, J.M., O'Connell, J.W., Botvinick, E.H., Newman, D., Munoz, L. J. Am. Coll. Cardiol. (1991) [Pubmed]
  38. Alterations in cat knee joint blood flow induced by electrical stimulation of articular afferents and efferents. Khoshbaten, A., Ferrell, W.R. J. Physiol. (Lond.) (1990) [Pubmed]
  39. m-Octopamine: normal occurrence with p-octopamine in mammalian sympathetic nerves. Ibrahim, K.E., Couch, M.W., Williams, C.M., Fregly, M.J., Midgley, J.M. J. Neurochem. (1985) [Pubmed]
  40. Effects of coculture of anterior and posterior pituitary cells on the responsiveness of lactotrophs to different secretagogues. Dymshitz, J., Ben-Jonathan, N. Endocrinology (1991) [Pubmed]
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