The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Epyc  -  epiphycan

Mus musculus

Synonyms: Dermatan sulfate proteoglycan 3, Dspg3, Epiphycan, PG-Lb, Pglb, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Epyc

  • One of these monoclonal antibodies (IgM; designated MO-225) reacts with PG-M, chick embryo cartilage proteoglycans (PG-H, PG-Lb, and PG-Lt), and bovine nasal cartilage proteoglycan, but not with Swarm rat chondrosarcoma proteoglycan [1].

High impact information on Epyc


Biological context of Epyc


Anatomical context of Epyc


Analytical, diagnostic and therapeutic context of Epyc

  • Reverse transcriptase PCR using degenerate oligonucleotide primers gave a cDNA fragment that might correspond to mouse PG-Lb [3].


  1. A monoclonal antibody that specifically recognizes a glucuronic acid 2-sulfate-containing determinant in intact chondroitin sulfate chain. Yamagata, M., Kimata, K., Oike, Y., Tani, K., Maeda, N., Yoshida, K., Shimomura, Y., Yoneda, M., Suzuki, S. J. Biol. Chem. (1987) [Pubmed]
  2. The gene structure and organization of mouse PG-Lb, a small chondroitin/dermatan sulphate proteoglycan. Iwata, Y., Shinomura, T., Kurita, K., Zako, M., Kimata, K. Biochem. J. (1998) [Pubmed]
  3. Occurrence of PG-Lb, a leucine-rich small chondroitin/dermatan sulphate proteoglycan in mammalian epiphyseal cartilage: molecular cloning and sequence analysis of the mouse cDNA. Kurita, K., Shinomura, T., Ujita, M., Zako, M., Kida, D., Iwata, H., Kimata, K. Biochem. J. (1996) [Pubmed]
  4. Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants. Danielson, K.G., Siracusa, L.D., Donovan, P.J., Iozzo, R.V. Mamm. Genome (1999) [Pubmed]
  5. Expression and localization of PG-Lb/epiphycan during mouse development. Johnson, J., Shinomura, T., Eberspaecher, H., Pinero, G., Decrombrugghe, B., Höök, M. Dev. Dyn. (1999) [Pubmed]
WikiGenes - Universities