Gene Review:
ADRA1B - adrenoceptor alpha 1B
Homo sapiens
Synonyms:
ADRA1, ALPHA1BAR, Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor
- Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers. Noda, H., Miyaji, Y., Nakanishi, A., Konishi, F., Miki, Y. Br. J. Cancer (2007)
- Patterns of alpha-1-adrenergic receptor expression in regenerating and neoplastic hepatic tissue. Kost, D.P., DeFrances, M.C., Lee, C.R., Michalopoulos, G.K. Pathobiology (1992)
- A. Al Khayer, I. Sedki and K. Adra on "Painless reduction of anterior shoulder dislocation by Kocher's method". Chitgopkar, S.D., Khan, n.u.l.l. Injury. (2006)
- Glucocorticoids induce transcription and expression of the alpha 1B adrenergic receptor gene in DTT1 MF-2 smooth muscle cells. Sakaue, M., Hoffman, B.B. J. Clin. Invest. (1991)
- Functional effects of protein kinase C activation on the human cardiac Na+ channel. Murray, K.T., Hu, N.N., Daw, J.R., Shin, H.G., Watson, M.T., Mashburn, A.B., George, A.L. Circ. Res. (1997)
- The adaptor complex 2 directly interacts with the alpha 1b-adrenergic receptor and plays a role in receptor endocytosis. Diviani, D., Lattion, A.L., Abuin, L., Staub, O., Cotecchia, S. J. Biol. Chem. (2003)
- Phospholipase Cdelta1 is a guanine nucleotide exchanging factor for transglutaminase II (Galpha h) and promotes alpha 1B-adrenoreceptor-mediated GTP binding and intracellular calcium release. Baek, K.J., Kang, S., Damron, D., Im, M. J. Biol. Chem. (2001)
- Haplotype block and superblock structures of the alpha1-adrenergic receptor genes reveal echoes from the chromosomal past. Buzas, B., Belfer, I., Hipp, H., Lorincz, I., Evans, C., Phillips, G., Taubman, J., Max, M.B., Goldman, D. Mol. Genet. Genomics (2004)
- Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. Hawes, B.E., Luttrell, L.M., Exum, S.T., Lefkowitz, R.J. J. Biol. Chem. (1994)
- Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. Schwinn, D.A., Lomasney, J.W., Lorenz, W., Szklut, P.J., Fremeau, R.T., Yang-Feng, T.L., Caron, M.G., Lefkowitz, R.J., Cotecchia, S. J. Biol. Chem. (1990)
- The alpha 1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogeneity. Schwinn, D.A., Page, S.O., Middleton, J.P., Lorenz, W., Liggett, S.B., Yamamoto, K., Lapetina, E.G., Caron, M.G., Lefkowitz, R.J., Cotecchia, S. Mol. Pharmacol. (1991)
- Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. Kjelsberg, M.A., Cotecchia, S., Ostrowski, J., Caron, M.G., Lefkowitz, R.J. J. Biol. Chem. (1992)
- Expression of alpha 1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: implications for alpha 1-adrenergic receptor subtype classification. Price, D.T., Chari, R.S., Berkowitz, D.E., Meyers, W.C., Schwinn, D.A. Mol. Pharmacol. (1994)
- Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go. Blitzer, R.D., Omri, G., De Vivo, M., Carty, D.J., Premont, R.T., Codina, J., Birnbaumer, L., Cotecchia, S., Caron, M.G., Lefkowitz, R.J. J. Biol. Chem. (1993)
- The pharmacological profile of cloned and stably expressed alpha 1b-adrenoceptor in CHO cells. Horie, K., Hirasawa, A., Tsujimoto, G. Eur. J. Pharmacol. (1994)
- Cycloheximide induces the alpha 1B adrenergic receptor gene by activation of transcription in DDT1 MF-2 smooth muscle cells. Hu, Z.W., Hoffman, B.B. Mol. Pharmacol. (1993)
- The effects of tamsulosin, a high affinity antagonist at functional alpha 1A- and alpha 1D-adrenoceptor subtypes. Noble, A.J., Chess-Williams, R., Couldwell, C., Furukawa, K., Uchyiuma, T., Korstanje, C., Chapple, C.R. Br. J. Pharmacol. (1997)
- Noradrenaline contractions of human prostate mediated by alpha 1A-(alpha 1c-) adrenoceptor subtype. Marshall, I., Burt, R.P., Chapple, C.R. Br. J. Pharmacol. (1995)
- Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5. Loftus, S.K., Shiang, R., Warrington, J.A., Bengtsson, U., McPherson, J.D., Wasmuth, J.J. Cytogenet. Cell Genet. (1994)
- Neuron specific alpha-adrenergic receptor expression in human cerebellum: implications for emerging cerebellar roles in neurologic disease. Schambra, U.B., Mackensen, G.B., Stafford-Smith, M., Haines, D.E., Schwinn, D.A. Neuroscience (2005)
- Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. Lee, K., Richardson, C.D., Razik, M.A., Kwatra, M.M., Schwinn, D.A. DNA Seq. (1998)
- Detection of alpha 1-adrenoceptor subtypes in human hypertrophied prostate by in situ hybridization. Moriyama, N., Kurimoto, S., Horie, S., Nasu, K., Tanaka, T., Yano, K., Hirano, H., Tsujimoto, G., Kawabe, K. Histochem. J. (1996)
- The alpha 1a and alpha 1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action. Cotecchia, S., Rossier, O., Fanelli, F., Leonardi, A., De Benedetti, P.G. Pharmaceutica acta Helvetiae. (2000)
- Southwestern blots for detection of a DNA binding protein recognizing the alpha 1B-adrenergic receptor gene promoter. Gao, B., Kunos, G. Methods Mol. Biol. (2000)