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Gene Review

Adra1b  -  adrenoceptor alpha 1B

Rattus norvegicus

Synonyms: Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor
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  1. Receptor subtype and intracellular signal transduction pathway associated with situs inversus induced by alpha 1 adrenergic stimulation in rat embryos. Fujinaga, M., Hoffman, B.B., Baden, J.M. Dev. Biol. (1994) [Pubmed]
  2. Altered protein kinase C regulation of phosphoinositide-coupled receptors in deoxycorticosterone acetate-salt hypertensive rats. Calderone, A., Oster, L., Moreau, P., Rouleau, J.L., Stewart, D.J., de Champlain, J. Hypertension (1994) [Pubmed]
  3. The effect of reserpine, desipramine and thyroid hormone on alpha 1a- and alpha 1b-adrenoceptor binding sites: evidence for a subtype-specific regulation. Hanft, G., Gross, G. British journal of clinical pharmacology. (1990) [Pubmed]
  4. Hypoxia/reoxygenation selectively impairs alpha 1b-adrenoceptor function in small mesenteric arteries. Gao, H., Korthuis, R.J., Benoit, J.N. Am. J. Physiol. (1996) [Pubmed]
  5. cAMP responsive element-mediated regulation of the gene transcription of the alpha 1B adrenergic receptor by thyrotropin. Kanasaki, M., Matsubara, H., Murasawa, S., Masaki, H., Nio, Y., Inada, M. J. Clin. Invest. (1994) [Pubmed]
  6. The rat alpha 1B adrenergic receptor gene middle promoter contains multiple binding sites for sequence-specific proteins including a novel ubiquitous transcription factor. Gao, B., Spector, M.S., Kunos, G. J. Biol. Chem. (1995) [Pubmed]
  7. Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor. Lattion, A.L., Diviani, D., Cotecchia, S. J. Biol. Chem. (1994) [Pubmed]
  8. Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei. Greenwood, B.N., Foley, T.E., Day, H.E., Burhans, D., Brooks, L., Campeau, S., Fleshner, M. Biol. Psychiatry (2005) [Pubmed]
  9. Effect of mechanical loading on vascular alpha 1D- and alpha 1B-adrenergic receptor expression. Clements, M.L., Banes, A.J., Faber, J.E. Hypertension (1997) [Pubmed]
  10. Alpha 1B-adrenoceptor interacts with multiple sites of transglutaminase II: characteristics of the interaction in binding and activation. Feng, J.F., Gray, C.D., Im, M.J. Biochemistry (1999) [Pubmed]
  11. The expression of alpha 1 adrenoceptor subtypes changes with age in the rat aorta. Gurdal, H., Tilakaratne, N., Brown, R.D., Fonseca, M., Friedman, E., Johnson, M.D. J. Pharmacol. Exp. Ther. (1995) [Pubmed]
  12. Evidence for an alpha 1-adrenoceptor subtype mediating adrenergic vasoconstriction in Wistar normotensive and stroke-prone spontaneously hypertensive rat kidney. Sattar, M.A., Johns, E.J. J. Cardiovasc. Pharmacol. (1994) [Pubmed]
  13. Characterization of stimulation of phosphoinositide hydrolysis by alpha 1-adrenergic agonists in adult rat hearts. Lazou, A., Fuller, S.J., Bogoyevitch, M.A., Orfali, K.A., Sugden, P.H. Am. J. Physiol. (1994) [Pubmed]
  14. Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons. Marek, G.J., Aghajanian, G.K. Eur. J. Pharmacol. (1996) [Pubmed]
  15. Separation of putative alpha 1A- and alpha 1B-adrenoceptor mediated components in the tension response of the rat vas deferens to electrical field stimulation. Mallard, N.J., Marshall, R.W., Sithers, A.J., Spriggs, T.L. Br. J. Pharmacol. (1992) [Pubmed]
  16. Determination of alpha 1-adrenoceptor subtype selectivity by [3H]-prazosin displacement studies in guinea-pig cerebral cortex and rat spleen membranes. Veenstra, D.M., van Buuren, K.J., Nijkamp, F.P. Br. J. Pharmacol. (1992) [Pubmed]
  17. Identification of a single alpha 1-adrenoceptor corresponding to the alpha 1A-subtype in rat submaxillary gland. Michel, A.D., Loury, D.N., Whiting, R.L. Br. J. Pharmacol. (1989) [Pubmed]
  18. Alpha 1b-adrenoceptors mediate renal tubular sodium and water reabsorption in the rat. Elhawary, A.M., Pang, C.C. Br. J. Pharmacol. (1994) [Pubmed]
  19. Analysis of alpha 1L-adrenoceptor pharmacology in rat small mesenteric artery. Stam, W.B., Van der Graaf, P.H., Saxena, P.R. Br. J. Pharmacol. (1999) [Pubmed]
  20. Functional distribution and role of alpha-1 adrenoceptor subtypes in the mesenteric vasculature of the rat. Kong, J.Q., Taylor, D.A., Fleming, W.W. J. Pharmacol. Exp. Ther. (1994) [Pubmed]
  21. Effects of tamsulosin metabolites at alpha-1 adrenoceptor subtypes. Taguchi, K., Saitoh, M., Sato, S., Asano, M., Michel, M.C. J. Pharmacol. Exp. Ther. (1997) [Pubmed]
  22. Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist. Quaglia, W., Pigini, M., Tayebati, S.K., Piergentili, A., Giannella, M., Leonardi, A., Taddei, C., Melchiorre, C. J. Med. Chem. (1996) [Pubmed]
  23. Both the cyclic AMP response element and the activator protein 2 binding site mediate basal and cyclic AMP-induced transcription from the dominant promoter of the rat alpha 1B-adrenergic receptor gene in DDT1MF-2 cells. Gao, B., Chen, J., Johnson, C., Kunos, G. Mol. Pharmacol. (1997) [Pubmed]
  24. Intracellular calcium and alpha 1b-adrenoceptor phosphorylation. García-Sáinz, J.A., Mendoza-Mendoza, A., Vázquez-Prado, J. Arch. Med. Res. (1999) [Pubmed]
  25. Actin isoform and alpha 1B-adrenoceptor gene expression in aortic and coronary smooth muscle is influenced by cyclical stretch. Lundberg, M.S., Sadhu, D.N., Grumman, V.E., Chilian, W.M., Ramos, K.S. In Vitro Cell. Dev. Biol. Anim. (1995) [Pubmed]
  26. Two alpha 1b-adrenergic receptor mRNAS expressed in Sprague-Dawley rat liver have distinct 5'-regions. Deng, C.L., Cornett, L.E. J. Recept. Res. (1994) [Pubmed]
  27. Distribution of alpha 1B-adrenergic receptor mRNA expression along rat nephron segments. Umemura, S., Yamaguchi, S., Tamura, K., Hibi, K., Nyui, N., Ishigami, T., Kihara, M., Yabana, M., Ishii, M. Kidney Int. (1997) [Pubmed]
  28. Alpha 1B-adrenergic receptors in rat renal microvessels. Canessa, L.M., Piccio, M.M., Vachvanichsanong, P., Sidhu, A., Porter, C.C., Robillard, J.E., Felder, R.A., Jose, P.A. Kidney Int. (1995) [Pubmed]
  29. Increased alpha 1B-adrenoreceptor mRNA levels in the rat kidney after thyroidectomy. Meister, B., Dagerlind, A., Nicholas, A.P., Hökfelt, T. Eur. J. Pharmacol. (1993) [Pubmed]
  30. Functional change of the balance between alpha 1A and alpha 1B adrenoceptor populations after transplantation of the vas deferens to the intestine. Pupo, A.S., Jurkiewicz, N.H., Jurkiewicz, A. Ann. N. Y. Acad. Sci. (1997) [Pubmed]
  31. Regulation of alpha 1b-adrenergic receptor gene expression in rat liver cell lines. Deng, C.L., Cornett, L.E. Biochim. Biophys. Acta (1994) [Pubmed]
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