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Gene Review

Ptdss1  -  phosphatidylserine synthase 1

Mus musculus

Synonyms: AU044268, AW539008, PSS-1, Phosphatidylserine synthase 1, Pssa, ...
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Disease relevance of Ptdss1


High impact information on Ptdss1


Chemical compound and disease context of Ptdss1


Biological context of Ptdss1


Anatomical context of Ptdss1


Associations of Ptdss1 with chemical compounds


Analytical, diagnostic and therapeutic context of Ptdss1


  1. Cloning and expression of mouse liver phosphatidylserine synthase-1 cDNA. Overexpression in rat hepatoma cells inhibits the CDP-ethanolamine pathway for phosphatidylethanolamine biosynthesis. Stone, S.J., Cui, Z., Vance, J.E. J. Biol. Chem. (1998) [Pubmed]
  2. Defining the importance of phosphatidylserine synthase 2 in mice. Bergo, M.O., Gavino, B.J., Steenbergen, R., Sturbois, B., Parlow, A.F., Sanan, D.A., Skarnes, W.C., Vance, J.E., Young, S.G. J. Biol. Chem. (2002) [Pubmed]
  3. Structure and expression of the murine phosphatidylserine synthase-1 gene. Sturbois-Balcerzak, B., Stone, S.J., Sreenivas, A., Vance, J.E. J. Biol. Chem. (2001) [Pubmed]
  4. Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2. Stone, S.J., Vance, J.E. Biochem. J. (1999) [Pubmed]
  5. Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes. Stone, S.J., Vance, J.E. J. Biol. Chem. (2000) [Pubmed]
  6. Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes. Ardail, D., Gasnier, F., Lermé, F., Simonot, C., Louisot, P., Gateau-Roesch, O. J. Biol. Chem. (1993) [Pubmed]
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