Gene Review:
EN2 - engrailed homeobox 2
Homo sapiens
Synonyms:
Homeobox protein en-2, Homeobox protein engrailed-2, Hu-En-2
- Deregulated expression of PAX5 in medulloblastoma. Kozmik, Z., Sure, U., Rüedi, D., Busslinger, M., Aguzzi, A. Proc. Natl. Acad. Sci. U.S.A. (1995)
- EN2 is a candidate oncogene in human breast cancer. Martin, N.L., Saba-El-Leil, M.K., Sadekova, S., Meloche, S., Sauvageau, G. Oncogene (2005)
- No association between the EN2 gene and autistic disorder. Zhong, H., Serajee, F.J., Nabi, R., Huq, A.H. J. Med. Genet. (2003)
- Cleft lip with or without cleft palate: associations with transforming growth factor alpha and retinoic acid receptor loci. Chenevix-Trench, G., Jones, K., Green, A.C., Duffy, D.L., Martin, N.G. Am. J. Hum. Genet. (1992)
- Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder. Gharani, N., Benayed, R., Mancuso, V., Brzustowicz, L.M., Millonig, J.H. Mol. Psychiatry (2004)
- An SstI RFLP for the human homeo box-containing gene EN2. Logan, C., Joyner, A.L. Nucleic Acids Res. (1989)
- Chromosomal localization of the human homeo box-containing genes, EN1 and EN2. Logan, C., Willard, H.F., Rommens, J.M., Joyner, A.L. Genomics (1989)
- Adverse effects of prenatal tobacco smoke exposure on biological parameters of the developing brainstem. Lavezzi, A.M., Ottaviani, G., Matturri, L. Neurobiol. Dis. (2005)
- Expression of the homeobox-containing genes EN1 and EN2 in human fetal midgestational medulla and cerebellum. Zec, N., Rowitch, D.H., Bitgood, M.J., Kinney, H.C. J. Neuropathol. Exp. Neurol. (1997)
- Agenesis of the mesencephalon and metencephalon with cerebellar hypoplasia: putative mutation in the EN2 gene--report of 2 cases in early infancy. Sarnat, H.B., Benjamin, D.R., Siebert, J.R., Kletter, G.B., Cheyette, S.R. Pediatr. Dev. Pathol. (2002)
- Cerebellum development and schizophrenia: an association study of the human homeogene Engrailed 2. Gourion, D., Leroy, S., Bourdel, M.C., Goldberger, C., Poirier, M.F., Olié, J.P., Krebs, M.O. Psychiatry research. (2004)
- Phosphorylation of isocarbostyril- and difluorophenyl-nucleoside thymidine mimics by the human deoxynucleoside kinases. Al-Madhoun, A.S., Eriksson, S., Wang, Z.X., Naimi, E., Knaus, E.E., Wiebe, L.I. Nucleosides Nucleotides Nucleic Acids (2004)
- The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans. Matsui, T., Hirai, M., Hirano, M., Kurosawa, Y. FEBS Lett. (1993)
- Tyrosine sulfation is not the last modification of entactin before its secretion from 3T3-L1 adipocytes. Aratani, Y., Kitagawa, Y. FEBS Lett. (1988)
- Single nucleotide polymorphisms in the chicken Lmbr1 gene are associated with chicken polydactyly. Huang, Y.Q., Deng, X.M., Du, Z.Q., Qiu, X., Du, X., Chen, W., Morisson, M., Leroux, S., Ponce de Léon, F.A., Da, Y., Li, N. Gene (2006)