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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Metencephalon


High impact information on Metencephalon


Biological context of Metencephalon


Anatomical context of Metencephalon


Associations of Metencephalon with chemical compounds


Gene context of Metencephalon

  • In the metencephalon, tal-2 expression was observed in the anterior pons, whereas tal-1 transcripts were detected in the entire pons, and showed stronger expression than tal-2 [14].
  • Agenesis of the mesencephalon and metencephalon with cerebellar hypoplasia: putative mutation in the EN2 gene--report of 2 cases in early infancy [15].
  • After the primary anterior-posterior patterning of the neural plate, a subset of wnt signaling molecules including Xwnt-1, Xwnt-2b, Xwnt-3A, Xwnt-8b are still expressed in the developing brain in a region spanning from the posterior part of the diencephalon to the mesencephalon/metencephalon boundary [16].
  • Fate mapping studies in chick have shown that at early stages the cerebellum derives from cells in the mesencephalon and metencephalon (mes-met) [17].
  • Proenkephalin-containing perikarya were located in all major subdivisions of the brain except the metencephalon [18].


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  9. Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes. Jagla, K., Dollé, P., Mattei, M.G., Jagla, T., Schuhbaur, B., Dretzen, G., Bellard, F., Bellard, M. Mech. Dev. (1995) [Pubmed]
  10. Sex steroids promote neurite growth in mesencephalic tyrosine hydroxylase immunoreactive neurons in vitro. Reisert, I., Han, V., Lieth, E., Toran-Allerand, D., Pilgrim, C., Lauder, J. Int. J. Dev. Neurosci. (1987) [Pubmed]
  11. Expression of cellular retinoic acid binding protein in the developing nervous system of mouse embryo. Momoi, M., Yamagata, T., Ichihashi, K., Yanagisawa, M., Yamakado, M., Momoi, T. Brain Res. Dev. Brain Res. (1990) [Pubmed]
  12. Primary dissociated cell culture of embryonic rat metencephalon: presence of GABA in serotonergic neurons. Belin, M.F., Fevre-Montange, M., Reboul, A., Didier-Bazes, M., Ehret, M., Maitre, M., Tardy, M. Neurosci. Lett. (1991) [Pubmed]
  13. Ontogeny of the metencephalic, mesencephalic and diencephalic content of catecholamines as measured by high performance liquid chromatography with electrochemical detection. Parés-Herbuté, N., Tapia-Arancibia, L., Astier, H. Int. J. Dev. Neurosci. (1989) [Pubmed]
  14. The leukemic oncogene tal-2 is expressed in the developing mouse brain. Mori, S., Sugawara, S., Kikuchi, T., Tanji, M., Narumi, O., Stoykova, A., Nishikawa, S.I., Yokota, Y. Brain Res. Mol. Brain Res. (1999) [Pubmed]
  15. Agenesis of the mesencephalon and metencephalon with cerebellar hypoplasia: putative mutation in the EN2 gene--report of 2 cases in early infancy. Sarnat, H.B., Benjamin, D.R., Siebert, J.R., Kletter, G.B., Cheyette, S.R. Pediatr. Dev. Pathol. (2002) [Pubmed]
  16. Autoregulation of canonical Wnt signaling controls midbrain development. Kunz, M., Herrmann, M., Wedlich, D., Gradl, D. Dev. Biol. (2004) [Pubmed]
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  18. Distribution of proenkephalin-derived peptides in the brain of Rana esculenta. Merchenthaler, I., Lázár, G., Maderdrut, J.L. J. Comp. Neurol. (1989) [Pubmed]
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