Gene Review:
tp53 - tumor protein p53
Danio rerio
Synonyms:
Cellular tumor antigen p53, SO:0000704, Tumor suppressor p53, brp53, drp53, ...
- tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Berghmans, S., Murphey, R.D., Wienholds, E., Neuberg, D., Kutok, J.L., Fletcher, C.D., Morris, J.P., Liu, T.X., Schulte-Merker, S., Kanki, J.P., Plasterk, R., Zon, L.I., Look, A.T. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Stem-cell leukemia: p53 deficiency mediated suppression of leukemic differentiation in C3H/He myeloid leukemia. Yoshida, K., Aizawa, S., Watanabe, K., Hirabayashi, Y., Inoue, T. Leuk. Res. (2002)
- Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. Chen, J., Ruan, H., Ng, S.M., Gao, C., Soo, H.M., Wu, W., Zhang, Z., Wen, Z., Lane, D.P., Peng, J. Genes Dev. (2005)
- Identification of p53 regulators by genome-wide functional analysis. Huang, Q., Raya, A., DeJesus, P., Chao, S.H., Quon, K.C., Caldwell, J.S., Chanda, S.K., Izpisua-Belmonte, J.C., Schultz, P.G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss. Campbell, W.A., Yang, H., Zetterberg, H., Baulac, S., Sears, J.A., Liu, T., Wong, S.T., Zhong, T.P., Xia, W. J. Neurochem. (2006)
- p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1. Plaster, N., Sonntag, C., Busse, C.E., Hammerschmidt, M. Cell Death Differ. (2006)
- Perp is required for tissue-specific cell survival during zebrafish development. Nowak, M., Köster, C., Hammerschmidt, M. Cell Death Differ. (2005)
- Specific and conserved roles of TAp73 during zebrafish development. Rentzsch, F., Kramer, C., Hammerschmidt, M. Gene (2003)
- Cloning and developmental expression of p73 cDNA in zebrafish. Pan, H., Dung, H.N., Hsu, H.M., Hsiao, K.M., Chen, L.Y. Biochem. Biophys. Res. Commun. (2003)
- Zebrafish (Danio rerio) p53 tumor suppressor gene: cDNA sequence and expression during embryogenesis. Cheng, R., Ford, B.L., O'Neal, P.E., Mathews, C.Z., Bradford, C.S., Thongtan, T., Barnes, D.W., Hendricks, J.D., Bailey, G.S. Mol. Marine Biol. Biotechnol. (1997)
- Pentachlorophenol treatment in vivo elevates point mutation rate in zebrafish p53 gene. Yin, D., Gu, Y., Li, Y., Wang, X., Zhao, Q. Mutat. Res. (2006)
- Requirement of nuclear localization and transcriptional activity of p53 for its targeting to the yolk syncytial layer (YSL) nuclei in zebrafish embryo and its use for apoptosis assay. Chen, G.D., Chou, C.M., Hwang, S.P., Wang, F.F., Chen, Y.C., Hung, C.C., Chen, J.Y., Huang, C.J. Biochem. Biophys. Res. Commun. (2006)