Gene Review:
brk - brinker
Drosophila melanogaster
Synonyms:
Brk, CG9653, Dm brk, Dmel\CG9653, ssg-1
- Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Müller, B., Hartmann, B., Pyrowolakis, G., Affolter, M., Basler, K. Cell (2003)
- Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker. Campbell, G., Tomlinson, A. Cell (1999)
- Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Moreno, E., Basler, K., Morata, G. Nature (2002)
- The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis. Torres-Vazquez, J., Park, S., Warrior, R., Arora, K. Development (2001)
- Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism. Yao, L.C., Blitz, I.L., Peiffer, D.A., Phin, S., Wang, Y., Ogata, S., Cho, K.W., Arora, K., Warrior, R. Development (2006)
- Repression of dpp targets by binding of brinker to mad sites. Kirkpatrick, H., Johnson, K., Laughon, A. J. Biol. Chem. (2001)
- The role of brinker in eggshell patterning. Chen, Y., Schüpbach, T. Mech. Dev. (2006)
- Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo. Zhang, H., Levine, M., Ashe, H.L. Genes Dev. (2001)
- Analysis of Drosophila salivary gland, epidermis and CNS development suggests an additional function of brinker in anterior-posterior cell fate specification. Lammel, U., Meadows, L., Saumweber, H. Mech. Dev. (2000)
- Brk, Srm, Frk, and Src42A form a distinct family of intracellular Src-like tyrosine kinases. Serfas, M.S., Tyner, A.L. Oncol. Res. (2003)
- Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. Sivasankaran, R., Vigano, M.A., Müller, B., Affolter, M., Basler, K. EMBO J. (2000)
- Schnurri mediates Dpp-dependent repression of brinker transcription. Marty, T., Müller, B., Basler, K., Affolter, M. Nat. Cell Biol. (2000)
- brinker and optomotor-blind act coordinately to initiate development of the L5 wing vein primordium in Drosophila. Cook, O., Biehs, B., Bier, E. Development (2004)
- The transcriptional repressor Brinker antagonizes Wingless signaling. Saller, E., Kelley, A., Bienz, M. Genes Dev. (2002)
- Dpp signaling thresholds in the dorsal ectoderm of the Drosophila embryo. Ashe, H.L., Mannervik, M., Levine, M. Development (2000)