Gene Review:
SUMO4 - small ubiquitin-like modifier 4
Homo sapiens
Synonyms:
IDDM5, SMT3H4, SUMO-4, Small ubiquitin-like protein 4, Small ubiquitin-related modifier 4, ...
- Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population. Tsurumaru, M., Kawasaki, E., Ida, H., Migita, K., Moriuchi, A., Fukushima, K., Fukushima, T., Abiru, N., Yamasaki, H., Noso, S., Ikegami, H., Awata, T., Sasaki, H., Eguchi, K. J. Clin. Endocrinol. Metab. (2006)
- Study of the role of functional variants of SLC22A4, RUNX1 and SUMO4 in systemic lupus erythematosus. Orozco, G., Sánchez, E., Gómez, L.M., González-Gay, M.A., López-Nevot, M.A., Torres, B., Ortego-Centeno, N., Jiménez-Alonso, J., de Ramón, E., Sánchez Román, J., Anaya, J.M., Sturfelt, G., Gunnarsson, I., Svennungsson, E., Alarcón-Riquelme, M., González-Escribano, M.F., Martín, J. Ann. Rheum. Dis. (2006)
- A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. Bohren, K.M., Nadkarni, V., Song, J.H., Gabbay, K.H., Owerbach, D. J. Biol. Chem. (2004)
- The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis. Gibbons, L.J., Thomson, W., Zeggini, E., Worthington, J., Barton, A., Eyre, S., Donn, R., Hinks, A. Rheumatology (Oxford, England) (2005)
- No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease. Jennings, C.E., Owen, C.J., Wilson, V., Pearce, S.H. Clin. Endocrinol. (Oxf) (2005)
- A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Guo, D., Li, M., Zhang, Y., Yang, P., Eckenrode, S., Hopkins, D., Zheng, W., Purohit, S., Podolsky, R.H., Muir, A., Wang, J., Dong, Z., Brusko, T., Atkinson, M., Pozzilli, P., Zeidler, A., Raffel, L.J., Jacob, C.O., Park, Y., Serrano-Rios, M., Larrad, M.T., Zhang, Z., Garchon, H.J., Bach, J.F., Rotter, J.I., She, J.X., Wang, C.Y. Nat. Genet. (2004)
- SUMO4 M55V Variant Is Associated With Diabetic Nephropathy in Type 2 Diabetes. Lin, H.Y., Wang, C.L., Hsiao, P.J., Lu, Y.C., Chen, S.Y., Lin, K.D., Hsin, S.C., Hsieh, M.C., Shin, S.J. Diabetes (2007)
- Genetic Heterogeneity in Association of the SUMO4 M55V Variant With Susceptibility to Type 1 Diabetes. Noso, S., Ikegami, H., Fujisawa, T., Kawabata, Y., Asano, K., Hiromine, Y., Tsurumaru, M., Sugihara, S., Lee, I., Kawasaki, E., Awata, T., Ogihara, T. Diabetes (2005)
- Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type 1 diabetes. Kosoy, R., Concannon, P. Genes Immun. (2005)
- Association of SUMO4 M55V Polymorphism with Autoimmune Diabetes in Latvian Patients. Sedimbi, S.K., Shastry, A., Park, Y., Rumba, I., Sanjeevi, C.B. Ann. N. Y. Acad. Sci. (2006)
- SLC22A4, RUNX1, and SUMO4 polymorphisms are not associated with rheumatoid arthritis: a case-control study in a Spanish population. Orozco, G., Sánchez, E., González-Gay, M.A., López-Nevot, M.A., Torres, B., Pascual-Salcedo, D., Balsa, A., Pablos, J.L., García, A., González-Escribano, M.F., Martín, J. J. Rheumatol. (2006)