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MeSH Review

Graves Disease

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Disease relevance of Graves Disease


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Chemical compound and disease context of Graves Disease


Biological context of Graves Disease


Anatomical context of Graves Disease


Gene context of Graves Disease


Analytical, diagnostic and therapeutic context of Graves Disease


  1. Administration of thyroxine in treated Graves' disease. Effects on the level of antibodies to thyroid-stimulating hormone receptors and on the risk of recurrence of hyperthyroidism. Hashizume, K., Ichikawa, K., Sakurai, A., Suzuki, S., Takeda, T., Kobayashi, M., Miyamoto, T., Arai, M., Nagasawa, T. N. Engl. J. Med. (1991) [Pubmed]
  2. Thyroid diseases after treatment of Hodgkin's disease. Hancock, S.L., Cox, R.S., McDougall, I.R. N. Engl. J. Med. (1991) [Pubmed]
  3. Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells. Londei, M., Bottazzo, G.F., Feldmann, M. Science (1985) [Pubmed]
  4. Postpartum thyrotoxicosis in a patient with Graves' disease. Association with low radioactive iodine uptake. Eckel, R.H., Green, W.L. JAMA (1980) [Pubmed]
  5. Type 2 iodothyronine deiodinase is highly expressed in human thyroid. Salvatore, D., Tu, H., Harney, J.W., Larsen, P.R. J. Clin. Invest. (1996) [Pubmed]
  6. Case study: missed diagnosis and mistreatment of unrecognized comorbid Graves disease. Woolston, J.L., Caracansi, A. Journal of the American Academy of Child and Adolescent Psychiatry. (1999) [Pubmed]
  7. Free radical activity and antioxidant defense mechanisms in patients with hyperthyroidism due to Graves' disease during therapy. Komosinska-Vassev, K., Olczyk, K., Kucharz, E.J., Marcisz, C., Winsz-Szczotka, K., Kotulska, A. Clin. Chim. Acta (2000) [Pubmed]
  8. Administration of thyroxine in treated Graves' disease. Medeiros-Neto, G. N. Engl. J. Med. (1991) [Pubmed]
  9. Induction of circulating activated suppressor-like T cells by methimazole therapy for Graves' disease. Tötterman, T.H., Karlsson, F.A., Bengtsson, M., Mendel-Hartvig, I. N. Engl. J. Med. (1987) [Pubmed]
  10. Antithyroid drug therapy for Graves' disease during pregnancy. Optimal regimen for fetal thyroid status. Momotani, N., Noh, J., Oyanagi, H., Ishikawa, N., Ito, K. N. Engl. J. Med. (1986) [Pubmed]
  11. Long-term follow-up study of compensated low-dose 131I therapy for Graves' disease. Sridama, V., McCormick, M., Kaplan, E.L., Fauchet, R., DeGroot, L.J. N. Engl. J. Med. (1984) [Pubmed]
  12. Carbimazole and the autoimmune response in Graves' disease. McGregor, A.M., Petersen, M.M., McLachlan, S.M., Rooke, P., Smith, B.R., Hall, R. N. Engl. J. Med. (1980) [Pubmed]
  13. Potassium iodide and propranolol in Graves' disease. Emerson, C.H., El-Zaheri, M.M. N. Engl. J. Med. (1980) [Pubmed]
  14. Remission of hyperthyroidims and oral contraceptive therapy. [Answer to question]. Selenkow, H.A. JAMA (1984) [Pubmed]
  15. Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices. Laurent, E., Van Sande, J., Ludgate, M., Corvilain, B., Rocmans, P., Dumont, J.E., Mockel, J. J. Clin. Invest. (1991) [Pubmed]
  16. Radioiodine treatment of Graves' disease. An assessment of its potential risks. Graham, G.D., Burman, K.D. Ann. Intern. Med. (1986) [Pubmed]
  17. An optimal treatment for pediatric Graves' disease is radioiodine. Rivkees, S.A., Dinauer, C. J. Clin. Endocrinol. Metab. (2007) [Pubmed]
  18. MHC class II region, CTLA4 gene, and ophthalmopathy in patients with Graves' disease. Allahabadia, A., Heward, J.M., Nithiyananthan, R., Gibson, S.M., Reuser, T.T., Dodson, P.M., Franklyn, J.A., Gough, S.C. Lancet (2001) [Pubmed]
  19. Association between the DRB1*08032 histocompatibility antigen and methimazole-induced agranulocytosis in Japanese patients with Graves disease. Tamai, H., Sudo, T., Kimura, A., Mukuta, T., Matsubayashi, S., Kuma, K., Nagataki, S., Sasazuki, T. Ann. Intern. Med. (1996) [Pubmed]
  20. Stimulation by thyroid-stimulating hormone and Grave's immunoglobulin G of vascular endothelial growth factor mRNA expression in human thyroid follicles in vitro and flt mRNA expression in the rat thyroid in vivo. Sato, K., Yamazaki, K., Shizume, K., Kanaji, Y., Obara, T., Ohsumi, K., Demura, H., Yamaguchi, S., Shibuya, M. J. Clin. Invest. (1995) [Pubmed]
  21. Thymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus. Murakami, M., Hosoi, Y., Negishi, T., Kamiya, Y., Miyashita, K., Yamada, M., Iriuchijima, T., Yokoo, H., Yoshida, I., Tsushima, Y., Mori, M. J. Clin. Invest. (1996) [Pubmed]
  22. Coma and thyrotoxicosis. Newcomer, J., Haire, W., Hartman, C.R. Ann. Neurol. (1983) [Pubmed]
  23. Hyperthyroxinemic mice have reduced natural killer cell activity. Evidence for a defective trigger mechanism. Stein-Streilein, J., Zakarija, M., Papic, M., McKenzie, J.M. J. Immunol. (1987) [Pubmed]
  24. IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy. Chen, B., Tsui, S., Smith, T.J. J. Immunol. (2005) [Pubmed]
  25. Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines. Mullins, R.J., Cohen, S.B., Webb, L.M., Chernajovsky, Y., Dayan, C.M., Londei, M., Feldmann, M. J. Clin. Invest. (1995) [Pubmed]
  26. Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease. Kallmann, B.A., Hüther, M., Tubes, M., Feldkamp, J., Bertrams, J., Gries, F.A., Lampeter, E.F., Kolb, H. Diabetes (1997) [Pubmed]
  27. HLA immunogenetic heterogeneity in black American patients with Graves' disease. Sridama, V., Hara, Y., Fauchet, R., DeGroot, L.J. Arch. Intern. Med. (1987) [Pubmed]
  28. Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Hussain, M.J., Peakman, M., Gallati, H., Lo, S.S., Hawa, M., Viberti, G.C., Watkins, P.J., Leslie, R.D., Vergani, D. Diabetologia (1996) [Pubmed]
  29. CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus. Donner, H., Rau, H., Walfish, P.G., Braun, J., Siegmund, T., Finke, R., Herwig, J., Usadel, K.H., Badenhoop, K. J. Clin. Endocrinol. Metab. (1997) [Pubmed]
  30. Ratio of serum triiodothyronine to thyroxine and the prognosis of triiodothyronine-predominant Graves' disease. Takamatsu, J., Sugawara, M., Kuma, K., Kobayashi, A., Matsuzuka, F., Mozai, T., Hershman, J.M. Ann. Intern. Med. (1984) [Pubmed]
  31. Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen. Chan, J.Y., Lerman, M.I., Prabhakar, B.S., Isozaki, O., Santisteban, P., Kuppers, R.C., Oates, E.L., Notkins, A.L., Kohn, L.D. J. Biol. Chem. (1989) [Pubmed]
  32. Unique autoantibody epitopes in an immunodominant region of thyroid peroxidase. Arscott, P.L., Koenig, R.J., Kaplan, M.M., Glick, G.D., Baker, J.R. J. Biol. Chem. (1996) [Pubmed]
  33. Insulin sensitivity and exogenous insulin clearance in Graves' disease. Measurement by the glucose clamp technique and continuous indirect calorimetry. Randin, J.P., Tappy, L., Scazziga, B., Jequier, E., Felber, J.P. Diabetes (1986) [Pubmed]
  34. Rectal administration of propylthiouracil in the treatment of Graves' disease. Walter, R.M., Bartle, W.R. Am. J. Med. (1990) [Pubmed]
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